Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and Wbanded mice and interfere with distinct steps in melanocyte development

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Anderson, D.M., Lyman, S. D., Baird, A., Wignall, J. M., Eisenman, J., Rauch, C., March, C. J., Boswell, H. S., Gimpel, S. D., Cosman, D. and Williams, D. E (1990). Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 63, 235-243.[Medline]

Bronner-Fraser, M (1986). Analysis of the early stages of trunk neural crest migration in avian embryos using monoclonal antibody HNK-1. Dev. Biol 115, 528-536.

Brunkow, M., Nagle, D., Bernstein, A. and Bucan, M (1995). A 1.8 Mb YAC contig spanning three members of the receptor tyrosine kinase gene family ( Pdgfra, Kit ,and Flk-1 ) on mouse chromosome 5. Genomics 25, 421-432.[Medline]

Chabot, B., Stephenson, D. A., Chapman, V. M., Besmer, P. and Bernstein, A (1988). The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature 335, 88-89.[Medline]

Copeland, N.G., Gilbert, D. J., Cho, B. C., Donovan, P. J., Jenkins, N. A., Cosman, D, Anderson, D., Lyman, S. D. and Williams, D. E (1990). Mast cell growth factor maps near the Steel locus on mouse chromosome 10 and is deleted in a number of Steel alleles. Cell 63, 175-183.[Medline]

De Sepulveda, P., Salaun, P., Maas, N., Andre, C. and Panthier, J.-J (1995). SARs do not impair position-dependent expression of a Kit/LacZ transgene. Bioch. Bioph. Res. Comm 211, 3-.

Duttlinger, R., Manova, K., Chu, T. Y., Gyssler, C. Zelentz, A. D., Bachvarova R. F. and Besmer, P (1993). W-sash affects positive and negative elements controlling c- kit expression: ectopic c- kit expression at sites of kit-ligand expression affects melanogenesis. Development 118, 705-717.[Abstract]

Duttlinger, R., Manova, K., Berrozpe, G., Chu, T. Y., DeLeon, V., Timokhina, I., Chaganti, R. S. K., Zelenetz, A. D., Bachvarova, R. F. and Besmer, P (1995). The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mice. Proc. Natl. Acad. Sci. USA 92, 3754-3758.[Abstract/Free Full Text]

Flanagan, J. G. and Leder, P (1990). The kit ligand: A cell surface molecule altered in Steel mutant fibroblasts. Cell 63, 185-194.[Medline]

Galli, S. J., Zsebo, K. M. and Geissler, E. N (1994). The kit ligand, Stem Cell Factor. Advances in Immunology 55, 1-96.[Medline]

Geissler, E. N., Ryan, M. A. and Houseman, D. E (1988). The dominant white spotting ( W ) locus of the mouse encodes the c-kit proto-oncogene. Cell 55, 185-194.[Medline]

Huang, E., Nocka, K., Beier, D. R., Chu, T. Y., Buck, J., Lahm, H.-W., Wellner, D., Leder, P. and Besmer, P (1990). The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63, 225-233.[Medline]

Huizinga, J. D., Thuneberg, L., Kluppel, M., Malysz, J., Mikkelsen, H. B. and Bernstein, A (1995). W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373, 347-349.[Medline]

Huszar, D., Sharpe, A. and Jaenisch, R (1991). Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras. Development 112, 131-141.[Abstract]

Keshet, E., Lyman, S. D., Williams, D. E., Anderson, D. M., Jenkins, N. A., Copeland, N. G. and Parada, L. F (1991). Embryonic RNA expression patterns of the c- kit receptor and its cognate ligand suggest multiple functional roles in mouse development. EMBO J 10, 2425-2435.[Medline]

Lassam, N., and Jay, G (1989). Suppression of MHC class I RNA in highly oncogenic cells occurs at the level of transcription initiation. J. Immunol 143, 3792-3797.[Abstract]

Loring, J. F. and Erickson, C. A (1987). Neural crest cell migratory pathways in the trunk of the chick embryo. Dev. Biol 121, 220-236.[Medline]

Lyon, M. F., and Glenister, P. H (1982). A new allele sash ( Wsh ) at the W -locus and a spontaneous recessive lethal in mice. Genet. Res 39, 315-322.[Medline]

Marks, D. L., Wiemann, J. N., Burton, K. A., Lent, K. L., Clifton, D. K. and Steiner, R. A (1992). Simultaneous visualization of two cellular mRNA species in individual neurons by use of a new double in situ hybridization method. Mol. Cel.l Neurosci 3, 395-405.

Matsui, Y., Zsebo, K. M. and Hogan, B. L. M (1990). Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit. Nature 347, 667-669.[Medline]

Mayer, T. C (1973). The migratory pathways of neural crest cells into the skin of mouse embryos. Dev. Biol 34, 39-46.[Medline]

Miller, M. A., Kolb, P. E. and Raskind, M. A (1993). A method for simultaneous detection of multiple mRNAs using digoxigenin and radioisotopic cRNA probes. J. Histochem. Cytochem 41, 1741-1750.[Abstract]

Motro, B., Van Der Kooy, D., Rossant, J., Reith, A. and Bernstein, A (1991). Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci. Development 113, 1207-1221.[Abstract]

Nagle, D. L., Martin-DeLeon, P., Hough, R. B. and Bucan, M (1994). Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph , W19H and Rw on mouse chromosome 5. Proc. Natl. Acad. Sci. USA 91, 7237-7241.[Abstract/Free Full Text]

Nagle, D. L., Kozak, C. A., Mano, H., Chapman, V. M. and Bucan, M (1995). Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion. Hum. Mol. Gen 4, 2073-2079.[Abstract/Free Full Text]

Nishikawa, S., Kusakabe, M., Yoshinaga, K., Ogawa, M., Hayashi, S., Kunisada, T., Era, T., Sakakura, T. and Nishikawa, S (1991). In utero manipulation of coat color formation by a monoclonal anti- c-kit antibody: two distinct waves of c-kit dependency during melanocyte development. EMBO J 10, 2111-2118.[Medline]

Nocka, K., Tan, J. C., Chiu, E., Chu, T. Y., Ray, P., Traktman, P. and Besmer, P (1990). Molecular bases of dominant negative and loss of function mutations at the murine c- kit / white spotting locus: W37 , Wv , W41 and W. EMBO J 9, 1805-1813.[Medline]

Orr-Urtreger, A., Avivi, A., Zimmer, Y., Givol, D., Yarden, Y. and Lonai, P (1990). Developmental expression of c- kit , a proto-oncogene encoded by the W locus. Development 109, 911-923.[Abstract/Free Full Text]

Reith, A. D., Rottapel, R., Giddens, E., Brady, C., Forrester, L. and Bernstein, L (1990). W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c- kit receptor. Genes Dev 4, 390-400.[Abstract/Free Full Text]

Scott, G., Ewing, J., Ryan, D. and Abboud, C (1994). Stem cell factor regulates human melanocyte-matrix interactions. Pigment Cell Res 7, 44-51.[Medline]

Serbedzija, G. N., Fraser, S. E. and Bronner-Fraser, M (1990). Pathways of trunk neural crest migration in the mouse embryo as revealed by vital dye labeling. Development 108, 605-612.[Abstract/Free Full Text]

Steel, K. P., Davidson, D. R. and Jackson, I. J (1992). Trp-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development 115, 1111-1119.[Abstract]

Ward, S., Burns, A., Torihashi, S. and Sanders, K (1994). Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rythmicity in murine intestine. J. Physiol 480, 91-97.

Wehrle-Haller, B. and Weston, J. A (1995). Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precurser dispersal and survival on the lateral neural crest migration pathway. Development 121, 731-742.[Abstract]

Williams, D. E., Eisenmann, J., Baird, A., Rauch, C., Van Ness, K., March, C. J., Park, L. S., Martin, U., Mochizuki, D. J., Boswell, H. S., Burgess, G. S., Cosman, D. and Lyman, S. D (1990). Identification of a ligand for the c-kit proto-oncogene. Cell 63, 167-174.[Medline]

Yasuda, H., Galli, S. J. and Geissler, E. N (1993). Cloning and functional analysis of the mouse c-kit promoter. Bioch. Bioph. Res. Comm 191, 3-.

Yoshida, H., Kunisada, T., Kusakabe, M., Nishikawa, S. and Nishikawa, S. I (1996). Distinct stages of melanocyte differentiation revealed by analysis of nonuniform pigmentation patterns. Development 122, 1207-1214.[Abstract]

Zsebo, K. M., Williams, D. A., Geissler, E. N., Broudy, V. C., Martin, F. H., Atkins, H. L., Hsu, R. Y., Birkett, N. C., Okino, K. H., Murdock, D. C., Jacobsen, F. W., Takeishi, T., Cattanach, B. M., Galli, S. J. and Suggs, S. V (1990). Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 63, 213-224.[Medline]

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				G. Berrozpe, V. Agosti, C. Tucker, C. Blanpain, K. Manova, and P. Besmer A Distant Upstream Locus Control Region Is Critical for Expression of the Kit Receptor Gene in Mast Cells Mol. Cell. Biol., August 1, 2006; 26(15): 5850 - 5860. [Abstract] [Full Text] [PDF]

				M. Kluppel, T. N. Wight, C. Chan, A. Hinek, and J. L. Wrana Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis Development, September 1, 2005; 132(17): 3989 - 4003. [Abstract] [Full Text] [PDF]

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				J. Cools, N. Mentens, M. D. Odero, P. Peeters, I. Wlodarska, M. Delforge, A. Hagemeijer, and P. Marynen Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13) Blood, March 1, 2002; 99(5): 1776 - 1784. [Abstract] [Full Text] [PDF]

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				R. J. DiLeone, G. A. Marcus, M. D. Johnson, and D. M. Kingsley Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes PNAS, February 15, 2000; 97(4): 1612 - 1617. [Abstract] [Full Text] [PDF]

				T Sun, D Jayatilake, G. Afink, P Ataliotis, M Nister, W. Richardson, and H. Smith A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth Development, January 11, 2000; 127(21): 4519 - 4529. [Abstract] [PDF]

				G. Berrozpe, I. Timokhina, S. Yukl, Y. Tajima, M. Ono, A. D. Zelenetz, and P. Besmer The Wsh, W57, and Ph Kit Expression Mutations Define Tissue-Specific Control Elements Located Between -23 and -154 kb Upstream of Kit Blood, October 15, 1999; 94(8): 2658 - 2666. [Abstract] [Full Text] [PDF]

				P. Lawinger, L. Rastelli, Z. Zhao, and S. Majumder Lack of Enhancer Function in Mammals Is Unique to Oocytes and Fertilized Eggs J. Biol. Chem., March 19, 1999; 274(12): 8002 - 8011. [Abstract] [Full Text] [PDF]

				B. J. Longley Jr., D. D. Metcalfe, M. Tharp, X. Wang, L. Tyrrell, S.-z. Lu, D. Heitjan, and Y. Ma Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis PNAS, February 16, 1999; 96(4): 1609 - 1614. [Abstract] [Full Text] [PDF]

				S Srinivas, Z Wu, C. Chen, V D'Agati, and F Costantini Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development Development, January 4, 1999; 126(7): 1375 - 1386. [Abstract] [PDF]

				R. B. Hough, A. Lengeling, V. Bedian, C. Lo, and M. Bucan Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6�and causes dysregulation of Kit expression PNAS, November 10, 1998; 95(23): 13800 - 13805. [Abstract] [Full Text] [PDF]

				S. Marklund, J. Kijas, H. Rodriguez-Martinez, L. Rönnstrand, K. Funa, M. Moller, D. Lange, I. Edfors-Lilja, and L. Andersson Molecular Basis for the Dominant White Phenotype in the Domestic Pig Genome Res., August 1, 1998; 8(8): 826 - 833. [Abstract] [Full Text]

				T Kunisada, H Yoshida, H Yamazaki, A Miyamoto, H Hemmi, E Nishimura, L. Shultz, S Nishikawa, and S Hayashi Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors Development, January 8, 1998; 125(15): 2915 - 2923. [Abstract] [PDF]

				An Extensive 3' Regulatory Region Controls Expression of Bmp5 in Specific Anatomical Structures of the Mouse Embryo Genetics, January 1, 1998; 148(1): 401 - 408.

				K Opdecamp, A Nakayama, M. Nguyen, C. Hodgkinson, W. Pavan, and H Arnheiter Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor Development, January 6, 1997; 124(12): 2377 - 2386. [Abstract] [PDF]