Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development

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L Gunhaga, T. Jessell, and T Edlund
Sonic hedgehog signaling at gastrula stages specifies ventral telencephalic cells in the chick embryo
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				I. Imayoshi, T. Shimogori, T. Ohtsuka, and R. Kageyama Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline Development, August 1, 2008; 135(15): 2531 - 2541. [Abstract] [Full Text] [PDF]

				B. Jin, Q. Tao, J. Peng, H. M. Soo, W. Wu, J. Ying, C. R. Fields, A. L. Delmas, X. Liu, J. Qiu, et al. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function Hum. Mol. Genet., March 1, 2008; 17(5): 690 - 709. [Abstract] [Full Text] [PDF]

				P. Heine, E. Dohle, K. Bumsted-O'Brien, D. Engelkamp, and D. Schulte Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development Development, March 1, 2008; 135(5): 805 - 811. [Abstract] [Full Text] [PDF]

				V. S. Mangale, K. E. Hirokawa, P. R. V. Satyaki, N. Gokulchandran, S. Chikbire, L. Subramanian, A. S. Shetty, B. Martynoga, J. Paul, M. V. Mai, et al. Lhx2 Selector Activity Specifies Cortical Identity and Suppresses Hippocampal Organizer Fate Science, January 18, 2008; 319(5861): 304 - 309. [Abstract] [Full Text] [PDF]

				S. L. Friedman Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver Physiol Rev, January 1, 2008; 88(1): 125 - 172. [Abstract] [Full Text] [PDF]

				B. Suter, R. S. Nowakowski, P. G. Bhide, and V. S. Caviness Navigating Neocortical Neurogenesis and Neuronal Specification: A Positional Information System Encoded by Neurogenetic Gradients J. Neurosci., October 3, 2007; 27(40): 10777 - 10784. [Abstract] [Full Text] [PDF]

				A. MacNeil, R. A. Pearson, R. E. MacLaren, A. J. Smith, J. C. Sowden, and R. R. Ali Comparative Analysis of Progenitor Cells Isolated from the Iris, Pars Plana, and Ciliary Body of the Adult Porcine Eye Stem Cells, October 1, 2007; 25(10): 2430 - 2438. [Abstract] [Full Text] [PDF]

				C. A. Lyssiotis, J. Walker, C. Wu, T. Kondo, P. G. Schultz, and X. Wu Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells PNAS, September 18, 2007; 104(38): 14982 - 14987. [Abstract] [Full Text] [PDF]

				K. K. Kim, S. B. Song, K. I. Kang, M. Rhee, and K. E. Kim Activation of the Thyroid-Stimulating Hormone {beta}-Subunit Gene by LIM Homeodomain Transcription Factor Lhx2 Endocrinology, July 1, 2007; 148(7): 3468 - 3476. [Abstract] [Full Text] [PDF]

				M. T. Pankratz, X.-J. Li, T. M. LaVaute, E. A. Lyons, X. Chen, and S.-C. Zhang Directed Neural Differentiation of Human Embryonic Stem Cells via an Obligated Primitive Anterior Stage Stem Cells, June 1, 2007; 25(6): 1511 - 1520. [Abstract] [Full Text] [PDF]

				H. Klassen, J. F. Kiilgaard, T. Zahir, B. Ziaeian, I. Kirov, E. Scherfig, K. Warfvinge, and M. J. Young Progenitor Cells from the Porcine Neural Retina Express Photoreceptor Markers After Transplantation to the Subretinal Space of Allorecipients Stem Cells, May 1, 2007; 25(5): 1222 - 1230. [Abstract] [Full Text] [PDF]

				O. Medina-Martinez and M. Jamrich Foxe view of lens development and disease Development, April 15, 2007; 134(8): 1455 - 1463. [Abstract] [Full Text] [PDF]

				B. Saha, P. Hari, D. Huilgol, and S. Tole Dual Role for LIM-Homeodomain Gene Lhx2 in the Formation of the Lateral Olfactory Tract J. Neurosci., February 28, 2007; 27(9): 2290 - 2297. [Abstract] [Full Text] [PDF]

				M. K. Sharma, D. B. Mansur, G. Reifenberger, A. Perry, J. R. Leonard, K. D. Aldape, M. G. Albin, R. J. Emnett, S. Loeser, M. A. Watson, et al. Distinct Genetic Signatures among Pilocytic Astrocytomas Relate to Their Brain Region Origin Cancer Res., February 1, 2007; 67(3): 890 - 900. [Abstract] [Full Text] [PDF]

				T. Rauch, H. Li, X. Wu, and G. P. Pfeifer MIRA-Assisted Microarray Analysis, a New Technology for the Determination of DNA Methylation Patterns, Identifies Frequent Methylation of Homeodomain-Containing Genes in Lung Cancer Cells Cancer Res., August 15, 2006; 66(16): 7939 - 7947. [Abstract] [Full Text] [PDF]

				X. Cheng, C.-m. Hsu, D. S. Currle, J. S. Hu, A. J. Barkovich, and E. S. Monuki Central roles of the roof plate in telencephalic development and holoprosencephaly. J. Neurosci., July 19, 2006; 26(29): 7640 - 7649. [Abstract] [Full Text] [PDF]

				H. Rhee, L. Polak, and E. Fuchs Lhx2 maintains stem cell character in hair follicles. Science, June 30, 2006; 312(5782): 1946 - 1949. [Abstract] [Full Text] [PDF]

				A. Seth, J. Culverwell, M. Walkowicz, S. Toro, J. M. Rick, S. C. F. Neuhauss, Z. M. Varga, and R. O. Karlstrom belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain Development, February 15, 2006; 133(4): 725 - 735. [Abstract] [Full Text] [PDF]

				E. Banin, A. Obolensky, M. Idelson, I. Hemo, E. Reinhardtz, E. Pikarsky, T. Ben-Hur, and B. Reubinoff Retinal Incorporation and Differentiation of Neural Precursors Derived from Human Embryonic Stem Cells Stem Cells, February 1, 2006; 24(2): 246 - 257. [Abstract] [Full Text] [PDF]

				J. Kimura, Y. Suda, D. Kurokawa, Z. M. Hossain, M. Nakamura, M. Takahashi, A. Hara, and S. Aizawa Emx2 and Pax6 Function in Cooperation with Otx2 and Otx1 to Develop Caudal Forebrain Primordium That Includes Future Archipallium J. Neurosci., May 25, 2005; 25(21): 5097 - 5108. [Abstract] [Full Text] [PDF]

				L. Muzio and A. Mallamaci Foxg1 Confines Cajal-Retzius Neuronogenesis and Hippocampal Morphogenesis to the Dorsomedial Pallium J. Neurosci., April 27, 2005; 25(17): 4435 - 4441. [Abstract] [Full Text] [PDF]

				D. Murali, S. Yoshikawa, R. R. Corrigan, D. J. Plas, M. C. Crair, G. Oliver, K. M. Lyons, Y. Mishina, and Y. Furuta Distinct developmental programs require different levels of Bmp signaling during mouse retinal development Development, March 1, 2005; 132(5): 913 - 923. [Abstract] [Full Text] [PDF]

				N. Gotoh, M. Ito, S. Yamamoto, I. Yoshino, N. Song, Y. Wang, I. Lax, J. Schlessinger, M. Shibuya, and R. A. Lang Tyrosine phosphorylation sites on FRS2{alpha} responsible for Shp2 recruitment are critical for induction of lens and retina PNAS, December 7, 2004; 101(49): 17144 - 17149. [Abstract] [Full Text] [PDF]

				E. Wandzioch, A. Kolterud, M. Jacobsson, S. L. Friedman, and L. Carlsson Lhx2-/- mice develop liver fibrosis PNAS, November 23, 2004; 101(47): 16549 - 16554. [Abstract] [Full Text] [PDF]

				A. Kolterud, M. Alenius, L. Carlsson, and S. Bohm The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity Development, November 1, 2004; 131(21): 5319 - 5326. [Abstract] [Full Text] [PDF]

				A. Ogura, K. Ikeo, and T. Gojobori Comparative Analysis of Gene Expression for Convergent Evolution of Camera Eye Between Octopus and Human Genome Res., August 1, 2004; 14(8): 1555 - 1561. [Abstract] [Full Text] [PDF]

				P. Alifragis, A. Liapi, and J. G. Parnavelas Lhx6 Regulates the Migration of Cortical Interneurons from the Ventral Telencephalon But Does Not Specify their GABA Phenotype J. Neurosci., June 16, 2004; 24(24): 5643 - 5648. [Abstract] [Full Text] [PDF]

				J. Hirota and P. Mombaerts The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons PNAS, June 8, 2004; 101(23): 8751 - 8755. [Abstract] [Full Text] [PDF]

				M. E. Zuber, G. Gestri, A. S. Viczian, G. Barsacchi, and W. A. Harris Specification of the vertebrate eye by a network of eye field transcription factors Development, November 1, 2003; 130(21): 5155 - 5167. [Abstract] [Full Text] [PDF]

				L. K. Bachir, G. Garrel, A. Lozach, J.-N. Laverriere, and R. Counis The Rat Pituitary Promoter of the Neuronal Nitric Oxide Synthase Gene Contains an Sp1-, LIM Homeodomain-Dependent Enhancer and a Distinct Bipartite Gonadotropin-Releasing Hormone-Responsive Region Endocrinology, September 1, 2003; 144(9): 3995 - 4007. [Abstract] [Full Text] [PDF]