spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sun, X.
Right arrow Articles by Artavanis-Tsakonas, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sun, X.
Right arrow Articles by Artavanis-Tsakonas, S.
Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E (1995). Notch signaling. Science 268, 225-232.[Abstract/Free Full Text]

Bowtell, D. D. L., Lila, T., Michael, W. M., Hackett, D. and Rubin, G. M (1991). Analysis of the enhancer element that controls expression of sevenless in the developing Drosophila eye. Proc. Natl. Acad. Sci.USA 88, 6853-6857.[Abstract/Free Full Text]

Brand, A. and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]

Brand, A. H. and Perrimon, N (1993). Targeted gene expression as a meansof altering cell fates and generating dominant phenotypes. Development 118, 401-415.

Cadigan, K. M. and Nusse, R (1996). wingless signalling in the Drosophila eye and embryonic epidermis. Development 122, 2801-2812.[Abstract]

Carthew, R. W. and Rubin, G. M (1990). seven in absentia , a gene required for specification of R7 cell fate in the Drosophila eye. Cell 63, 561-577.[Medline]

Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D. and Kintner, C (1995). Primary neurogenesis in Xenopus embryos regulated by a homolog of the Drosophila neurogenic gene Delta. Nature 375, 761-766.[Medline]

de Celis, J. F. and Garcia-Bellido, A (1994). Roles of the Notch gene in Drosophila wing morphogenesis. Mech. Dev 46, 109-122.[Medline]

de Celis, J. F. and Garcia-Bellido, A (1994). Roles of the Notch gene in Drosophila wing morphogenesis. Mech. Dev 46, 109-122.

de Celis, J. F., Garcia-Bellido, A. and Bray, S. J (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.[Abstract]

Diaz-Benjumea, F. J. and Cohen, S. M (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.[Abstract]

Diederich, R. J., Matsuno, K., Hing, H. and Artavanis-Tsakonas, S (1994). Cytosolic interaction between Deltex and Notch ankyrin repeats implicates Deltex in the Notch signaling pathway. Development 120, 473-481.[Abstract]

Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand in Drosophila wing formation. Genes Dev 10, 421-434.[Abstract/Free Full Text]

Fehon, R. G., Johansen, K. and Artavanis-Tsakonas, S (1991). Complex Cellular and Subcellular Regulation of Notch Expression during Embryonic and Imaginal Development of Drosophila : Implications for Notch Function. J. Cell Biol 113, 657-669.[Abstract/Free Full Text]

Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. and Artavanis-Tsakonas, S (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta , two EGF-homologous genes in Drosophila. Cell 61, 523-534.[Medline]

Fitzgerald, K. and Greenwald, I (1995). Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo. Development 121, 4275-4282.[Abstract]

Fleming, R. J., Scottgale, T. M., Diederich, R. J. and Artavanis-Tsakonas, S (1990). The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes Dev 4, 2188-2201.[Abstract/Free Full Text]

Fleming, R. J., Gu, Y. and Hukriede, N. A (1997). Serrate -mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc. Development 124, 2973-2981.[Abstract]

Fortini, M. E. and Artavanis-Tsakonas, S (1994). The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79, 273-282.[Medline]

Gaul, U., Mardon, G. and Rubin, G. M (1992). A putative Ras GTPase activating protein acts as a negative regulator of signaling by the sevenless receptor tyrosine kinase. Cell 68, 1007-1019.[Medline]

Gu, Y., Hukriede, N. A. and Fleming, R. J (1995). Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo. Development 121, 855-865.[Abstract]

Hay, B. A., Wolff, T. and Rubin, G. M (1994). Expression of baculovirus P35 prevents cell death in Drosophila. Development 120, 2121-2129.[Abstract]

Henderson, S. T., Gao, D., Lambie, E. J. and Kimble, J (1994). lag-2 may encode a signaling ligand for the Glp-1 and Lin-12 receptors of C. elegans. Development 120, 2913-2924.[Abstract]

Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D (1995). Expression of a Delta homolog in prospective neurons in the chick. Nature 375, 787-790.[Medline]

Hukriede, N. A. and Fleming, R. J (1997). Beaded of Goldschmidt , an antimorphic allele of Serrate , encodes a protein lacking transmembrane and intracellular domains. Genetics 145, 359-374.[Abstract]

Irvine, K. D. and Wieschaus, E (1994). fringe , a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606.[Medline]

Jennings, B., Celis, J. D., Delidakis, C., Preiss, A. and Bray, S (1995). Roles of Notch and achaete-scute complex in the expression of Enhancer of split bHLH proteins. Development 121, 3745-3752.[Abstract]

Jennings, B., Preiss, A., Delidakis, C. and Bray, S (1994). The Notchsignaling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 120, 3537-3548.[Abstract]

Kim, J., Irvine, K. D. and Carroll, S. B (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.[Medline]

Kim, J., Sebring, A., Esch, J. J., Kraus, M. E., Vorwerk, K., Magee, J. and Carroll, S. B (1996). Intergration of positional signals and regulation of wing formation and identity by Drosophilavestigial gene. Nature 382, 133-138.[Medline]

Kooh, P. J., Fehon, R. G. and Muskavitch, M. A. T (1993). Implicatons of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 431-440.[Abstract]

Kopczynski, C. C., Alton, A. K., Fechtel, K., Kooh, P. H. and Muskavitch, M. A (1988). Delta , a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factors of vertebrates. Genes and Development 2, 1723-1735.[Abstract/Free Full Text]

Lindsell, C. E., Shawber, C. J., Boulter, J. and Weinmaster, G (1995). Jagged: a mammalian ligand that activates Notch1. Cell 80, 909-917.[Medline]

Markopoulou, K., Welshons, W. J. and Artavanis-Tsakonas, S (1989). Phenotypic and molecular characterization of the facet alleles, a group of intronic mutations at the Notch locus of Drosophilamelanogaster. Genetics 122, 417-428.[Abstract/Free Full Text]

Mello, C. C., Draper, B. W. and Priess, J. R (1994). The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo. Cell 77, 95-106.[Medline]

Muskavitch, M. A. T (1994). Delta-Notch signaling and Drosophila cell fate choice. Dev. Biol 166, 415-430.[Medline]

Parks, A. L., Turner, F. R. and Muskavitch, M. A. T (1995). Relationships between complex Delta expression and the specification of retinal cell fates during Drosophila eye development. Mech. Dev 50, 201-216.[Medline]

Parody, T. R. and Muskavitch, M. A. T (1993). The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster. Genetics 135, 527-539.[Abstract]

Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.[Medline]

Speicher, S. A., Thomas, U., Hinz, U. and Knust, E (1994). The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 120, 535-544.[Abstract]

Sun, X. and Artavanis-Tsakonas, S (1996). The intracellular deletions of DELTA and SERRATE define dominant negative forms of the Drosophila Notch ligands. Development 122, 2465-2474.[Abstract]

Tax, F. E., Yeargers, J. J. and Thomas, J. H (1994). Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila. Nature 368, 150-154.[Medline]

Thomas, U., Speicher, S. A. and Knust, E (1991). The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs. Development 111, 749-761.[Abstract]

Thummel, C. S. and Pirrotta, V (1992). New pCaSpeR P element vectors. Drosophila information Service 71, 150-.

V\212ssin, H., Bremer, K. A., Knust, E. and Campos-Ortega, J. A (1987). The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats. EMBO J 6, 3433-3440.




This article has been cited by other articles:


Home page
J. Cell Sci.Home page
W. R. Gordon, K. L. Arnett, and S. C. Blacklow
The molecular logic of Notch signaling - a structural and biochemical perspective
J. Cell Sci., October 1, 2008; 121(19): 3109 - 3119.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. Li, Y. Li, W. Wu, W. R. Gordon, D. W. Chang, M. Lu, S. Scoggin, T. Fu, L. Vien, G. Histen, et al.
Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3
J. Biol. Chem., March 21, 2008; 283(12): 8046 - 8054.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. Lahmar, C. Catelain, S. Poirault, M. Dorsch, J.-L. Villeval, W. Vainchenker, O. Albagli, and E. Lauret
Distinct Effects of the Soluble Versus Membrane-Bound Forms of the Notch Ligand Delta-4 on Human CD34+CD38low Cell Expansion and Differentiation
Stem Cells, March 1, 2008; 26(3): 621 - 629.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
J.-L. Li, R. C.A. Sainson, W. Shi, R. Leek, L. S. Harrington, M. Preusser, S. Biswas, H. Turley, E. Heikamp, J. A. Hainfellner, et al.
Delta-like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, and Promotes Tumor Growth In vivo
Cancer Res., December 1, 2007; 67(23): 11244 - 11253.
[Abstract] [Full Text] [PDF]


Home page
Hum Mol GenetHome page
J. B.-D. Ponio, C. Wright-Crosnier, M.-T. Groyer-Picard, C. Driancourt, I. Beau, M. Hadchouel, and M. Meunier-Rotival
Biological function of mutant forms of JAGGED1 proteins in Alagille syndrome: inhibitory effect on Notch signaling
Hum. Mol. Genet., November 15, 2007; 16(22): 2683 - 2692.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
X. Li, E. Calvo, M. Cool, P. Chrobak, D. G. Kay, and P. Jolicoeur
Overexpression of Notch1 Ectodomain in Myeloid Cells Induces Vascular Malformations through a Paracrine Pathway
Am. J. Pathol., January 1, 2007; 170(1): 399 - 415.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. Pitsouli and C. Delidakis
The interplay between DSL proteins and ubiquitin ligases in Notch signaling
Development, September 15, 2005; 132(18): 4041 - 4050.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
S. K. Pallavi and L. S. Shashidhara
Signaling interactions between squamous and columnar epithelia of the Drosophila wing disc
J. Cell Sci., August 1, 2005; 118(15): 3363 - 3370.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
E. Mizuhara, T. Nakatani, Y. Minaki, Y. Sakamoto, Y. Ono, and Y. Takai
MAGI1 Recruits Dll1 to Cadherin-based Adherens Junctions and Stabilizes It on the Cell Surface
J. Biol. Chem., July 15, 2005; 280(28): 26499 - 26507.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
L. C. Nehring, A. Miyamoto, P. W. Hein, G. Weinmaster, and J. M. Shipley
The Extracellular Matrix Protein MAGP-2 Interacts with Jagged1 and Induces Its Shedding from the Cell Surface
J. Biol. Chem., May 27, 2005; 280(21): 20349 - 20355.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
E. C. Lai, F. Roegiers, X. Qin, Y. N. Jan, and G. M. Rubin
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta
Development, May 15, 2005; 132(10): 2319 - 2332.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
R. Le Borgne, A. Bardin, and F. Schweisguth
The roles of receptor and ligand endocytosis in regulating Notch signaling
Development, April 15, 2005; 132(8): 1751 - 1762.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
X. Tian, D. Hansen, T. Schedl, and J. B. Skeath
Epsin potentiates Notch pathway activity in Drosophila and C. elegans
Development, December 1, 2004; 131(23): 5807 - 5815.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
S. K. Pallavi and L. S. Shashidhara
Egfr/Ras pathway mediates interactions between peripodial and disc proper cells in Drosophila wing discs
Development, October 15, 2003; 130(20): 4931 - 4941.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
T. Schroeder, H. Kohlhof, N. Rieber, and U. Just
Notch Signaling Induces Multilineage Myeloid Differentiation and Up-Regulates PU.1 Expression
J. Immunol., June 1, 2003; 170(11): 5538 - 5548.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. Small, D. Kovalenko, R. Soldi, A. Mandinova, V. Kolev, R. Trifonova, C. Bagala, D. Kacer, C. Battelli, L. Liaw, et al.
Notch Activation Suppresses Fibroblast Growth Factor-dependent Cellular Transformation
J. Biol. Chem., April 25, 2003; 278(18): 16405 - 16413.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. M. Ascano, L. J. Beverly, and A. J. Capobianco
The C-terminal PDZ-Ligand of JAGGED1 Is Essential for Cellular Transformation
J. Biol. Chem., February 28, 2003; 278(10): 8771 - 8779.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
K. Mishra-Gorur, M. D. Rand, B. Perez-Villamil, and S. Artavanis-Tsakonas
Down-regulation of Delta by proteolytic processing
J. Cell Biol., October 28, 2002; 159(2): 313 - 324.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
V. Lindner, C. Booth, I. Prudovsky, D. Small, T. Maciag, and L. Liaw
Members of the Jagged/Notch Gene Families Are Expressed in Injured Arteries and Regulate Cell Phenotype via Alterations in Cell Matrix and Cell-Cell Interaction
Am. J. Pathol., September 1, 2001; 159(3): 875 - 883.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
C. D. Hoemann, N. Beaulieu, L. Girard, N. Rebai, and P. Jolicoeur
Two Distinct Notch1 Mutant Alleles Are Involved in the Induction of T-Cell Leukemia in c-myc Transgenic Mice
Mol. Cell. Biol., June 1, 2000; 20(11): 3831 - 3842.
[Abstract] [Full Text]


Home page
BloodHome page
K. Ohishi, B. Varnum-Finney, D. Flowers, C. Anasetti, D. Myerson, and I. D. Bernstein
Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1
Blood, May 1, 2000; 95(9): 2847 - 2854.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
B Varnum-Finney, L Wu, M Yu, C Brashem-Stein, S Staats, D Flowers, J. Griffin, and I. Bernstein
Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling
J. Cell Sci., January 12, 2000; 113(23): 4313 - 4318.
[Abstract] [PDF]


Home page
DevelopmentHome page
C Goutte, W Hepler, K. Mickey, and J. Priess
aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling
Development, January 6, 2000; 127(11): 2481 - 2492.
[Abstract] [PDF]


Home page
DevelopmentHome page
A. Parks, K. Klueg, J. Stout, and M. Muskavitch
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
Development, January 4, 2000; 127(7): 1373 - 1385.
[Abstract] [PDF]


Home page
J. Cell Sci.Home page
K. Klueg and M. Muskavitch
Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila
J. Cell Sci., January 10, 1999; 112(19): 3289 - 3297.
[Abstract] [PDF]


Home page
ScienceHome page
H. Qi, M. D. Rand, X. Wu, N. Sestan, W. Wang, P. Rakic, T. Xu, and S. Artavanis-Tsakonas
Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian
Science, January 1, 1999; 283(5398): 91 - 94.
[Abstract] [Full Text]


Home page
Mol. Biol. CellHome page
K. M. Klueg, T. R. Parody, and M. A.T. Muskavitch
Complex Proteolytic Processing Acts on Delta, a Transmembrane Ligand for Notch, during Drosophila Development
Mol. Biol. Cell, July 1, 1998; 9(7): 1709 - 1723.
[Abstract] [Full Text]


Home page
BloodHome page
B. Varnum-Finney, L. E. Purton, M. Yu, C. Brashem-Stein, D. Flowers, S. Staats, K. A. Moore, I. Le Roux, R. Mann, G. Gray, et al.
The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells
Blood, June 1, 1998; 91(11): 4084 - 4091.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. Go, D. Eastman, and S Artavanis-Tsakonas
Cell proliferation control by Notch signaling in Drosophila development
Development, January 6, 1998; 125(11): 2031 - 2040.
[Abstract] [PDF]


Home page
J. Cell Sci.Home page
E. Sevrioukov, J. Walenta, A Sunio, M Phistry, and H Kramer
Oligomerization of the extracellular domain of Boss enhances its binding to the Sevenless receptor and its antagonistic effect on R7 induction
J. Cell Sci., January 3, 1998; 111(6): 737 - 747.
[Abstract] [PDF]


Home page
DevelopmentHome page
N. Hukriede, Y Gu, and R. Fleming
A dominant-negative form of Serrate acts as a general antagonist of Notch activation
Development, January 9, 1997; 124(17): 3427 - 3437.
[Abstract] [PDF]


Home page
J. Biol. Chem.Home page
D. Small, D. Kovalenko, D. Kacer, L. Liaw, M. Landriscina, C. Di Serio, I. Prudovsky, and T. Maciag
Soluble Jagged 1 Represses the Function of Its Transmembrane Form to Induce the Formation of the Src-dependent Chord-like Phenotype
J. Biol. Chem., August 17, 2001; 276(34): 32022 - 32030.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
S. Kurata, M. J. Go, S. Artavanis-Tsakonas, and W. J. Gehring
Notch signaling and the determination of appendage identity
PNAS, February 29, 2000; 97(5): 2117 - 2122.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sun, X.
Right arrow Articles by Artavanis-Tsakonas, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sun, X.
Right arrow Articles by Artavanis-Tsakonas, S.