Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb

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				L. A. Lettice, A. E. Hill, P. S. Devenney, and R. E. Hill Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly Hum. Mol. Genet., April 1, 2008; 17(7): 978 - 985. [Abstract] [Full Text] [PDF]

				T. Suzuki, S. M. Hasso, and J. F. Fallon Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity PNAS, March 18, 2008; 105(11): 4185 - 4190. [Abstract] [Full Text] [PDF]

				C. A. Podlasek, C. L. Meroz, Y. Tang, K. E. McKenna, and K. T. McVary Regulation of Cavernous Nerve Injury-Induced Apoptosis by Sonic Hedgehog Biol Reprod, January 1, 2007; 76(1): 19 - 28. [Abstract] [Full Text] [PDF]

				L. Panman, A. Galli, N. Lagarde, O. Michos, G. Soete, A. Zuniga, and R. Zeller Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling Development, September 1, 2006; 133(17): 3419 - 3428. [Abstract] [Full Text] [PDF]

				Y. Li, H. Zhang, Y. Litingtung, and C. Chiang Cholesterol modification restricts the spread of Shh gradient in the limb bud PNAS, April 25, 2006; 103(17): 6548 - 6553. [Abstract] [Full Text] [PDF]

				K. Saha and D. V. Schaffer Signal dynamics in Sonic hedgehog tissue patterning Development, March 1, 2006; 133(5): 889 - 900. [Abstract] [Full Text] [PDF]

				H. L. Ashe and J. Briscoe The interpretation of morphogen gradients Development, February 1, 2006; 133(3): 385 - 394. [Abstract] [Full Text] [PDF]

				J. M. Verheyden, M. Lewandoski, C. Deng, B. D. Harfe, and X. Sun Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning Development, October 1, 2005; 132(19): 4235 - 4245. [Abstract] [Full Text] [PDF]

				J. Bok, M. Bronner-Fraser, and D. K. Wu Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear Development, May 1, 2005; 132(9): 2115 - 2124. [Abstract] [Full Text] [PDF]

				L. M. Zeltser Shh-dependent formation of the ZLI is opposed by signals from the dorsal diencephalon Development, May 1, 2005; 132(9): 2023 - 2033. [Abstract] [Full Text] [PDF]

				A. J. Zhu and M. P. Scott Incredible journey: how do developmental signals travel through tissue? Genes & Dev., December 15, 2004; 18(24): 2985 - 2997. [Abstract] [Full Text] [PDF]

				P. J. Scherz, B. D. Harfe, A. P. McMahon, and C. J. Tabin The Limb Bud Shh-Fgf Feedback Loop Is Terminated by Expansion of Former ZPA Cells Science, July 16, 2004; 305(5682): 396 - 399. [Abstract] [Full Text] [PDF]

				Y. Chen, V. Knezevic, V. Ervin, R. Hutson, Y. Ward, and S. Mackem Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh Development, May 15, 2004; 131(10): 2339 - 2347. [Abstract] [Full Text] [PDF]

				M.-H. Chen, Y.-J. Li, T. Kawakami, S.-M. Xu, and P.-T. Chuang Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates Genes & Dev., March 15, 2004; 18(6): 641 - 659. [Abstract] [Full Text] [PDF]

				T. Tabata and Y. Takei Morphogens, their identification and regulation Development, February 15, 2004; 131(4): 703 - 712. [Abstract] [Full Text] [PDF]

				O. Krebs, C. M. Schreiner, W. J. Scott Jr, S. M. Bell, D. J. Robbins, J. A. Goetz, H. Alt, N. Hawes, E. Wolf, and J. Favor Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud Development, December 15, 2003; 130(24): 6037 - 6047. [Abstract] [Full Text] [PDF]

				D. Treichel, F. Schock, H. Jackle, P. Gruss, and A. Mansouri mBtd is required to maintain signaling during murine limb development Genes & Dev., November 1, 2003; 17(21): 2630 - 2635. [Abstract] [Full Text] [PDF]

				K. L. Hammond, H. E. Loynes, A. A. Folarin, J. Smith, and T. T. Whitfield Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle Development, April 1, 2003; 130(7): 1403 - 1417. [Abstract] [Full Text] [PDF]

				T. Kawakami, T'N. Kawcak, Y.-J. Li, W. Zhang, Y. Hu, and P.-T. Chuang Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling Development, March 14, 2003; 129(24): 5753 - 5765. [Abstract] [Full Text] [PDF]

				M. Crozatier, B. Glise, and A. Vincent Connecting Hh, Dpp and EGF signalling in patterning of the Drosophila wing; the pivotal role of collier/knot in the AP organiser Development, March 11, 2003; 129(18): 4261 - 4269. [Abstract] [Full Text] [PDF]

				M. A. Ros, R. D. Dahn, M. Fernandez-Teran, K. Rashka, N. C. Caruccio, S. M. Hasso, J. J. Bitgood, J. J. Lancman, and J. F. Fallon The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb Development, February 1, 2003; 130(3): 527 - 537. [Abstract] [Full Text] [PDF]

				C. A. Podlasek, D. J. Zelner, H. B. Jiang, Y. Tang, J. Houston, K. E. McKenna, and K. T. McVary Sonic hedgehog Cascade Is Required for Penile Postnatal Morphogenesis, Differentiation, and Adult Homeostasis Biol Reprod, February 1, 2003; 68(2): 423 - 438. [Abstract] [Full Text] [PDF]

				Z. Zhang, Y. Song, X. Zhao, X. Zhang, C. Fermin, and Y. Chen Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis Development, September 1, 2002; 129(17): 4135 - 4146. [Abstract] [Full Text] [PDF]

				J. B. Rubin, Y. Choi, and R. A. Segal Cerebellar proteoglycans regulate sonic hedgehog responses during development Development, January 5, 2002; 129(9): 2223 - 2232. [Abstract] [Full Text] [PDF]

				M. Dyer, S. Farrington, D Mohn, J. Munday, and M. Baron Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo Development, January 5, 2001; 128(10): 1717 - 1730. [Abstract] [PDF]

				J. V. Brigande, A. E. Kiernan, X. Gao, L. E. Iten, and D. M. Fekete Molecular genetics of pattern formation in the inner ear: Do compartment boundaries play a role? PNAS, October 24, 2000; 97(22): 11700 - 11706. [Abstract] [Full Text] [PDF]

				R. D. Dahn and J. F. Fallon Interdigital Regulation of Digit Identity and Homeotic Transformation by Modulated BMP Signaling Science, July 21, 2000; 289(5478): 438 - 441. [Abstract] [Full Text]

				R. K. Guy Inhibition of sonic hedgehog autoprocessing in cultured mammalian cells by sterol deprivation PNAS, June 20, 2000; 97(13): 7307 - 7312. [Abstract] [Full Text] [PDF]

				M. Fernandez-Teran, M. E. Piedra, I. S. Kathiriya, D. Srivastava, J. C. Rodriguez-Rey, and M. A. Ros Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway Development, May 15, 2000; 127(10): 2133 - 2142. [Abstract] [PDF]

				R. B. Pepinsky, P. Rayhorn, E. S. Day, A. Dergay, K. P. Williams, A. Galdes, F. R. Taylor, P. A. Boriack-Sjodin, and E. A. Garber Mapping Sonic Hedgehog-Receptor Interactions by Steric Interference J. Biol. Chem., April 6, 2000; 275(15): 10995 - 11001. [Abstract] [Full Text] [PDF]