Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads

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[Abstract] [PDF]

J. LeSueur and J. Graff
Spemann organizer activity of Smad10
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[Abstract] [PDF]

S. Souchelnytskyi, T. Nakayama, A. Nakao, A. Moren, C.-H. Heldin, J. L. Christian, and P. ten Dijke
Physical and Functional Interaction of Murine and Xenopus Smad7 with Bone Morphogenetic Protein Receptors and Transforming Growth Factor-beta Receptors
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[Abstract] [Full Text] [PDF]

Y.-G. Chen, A. Hata, R. S. Lo, D. Wotton, Y. Shi, N. Pavletich, and J. Massagué
Determinants of specificity in TGF-beta signal�transduction
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[Abstract] [Full Text]

X.-H. Feng, Y. Zhang, R.-Y. Wu, and R. Derynck
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-beta -induced transcriptional�activation
Genes & Dev., July 15, 1998; 12(14): 2153 - 2163.
[Abstract] [Full Text]

T. Sykes, A. Rodaway, M. Walmsley, and R. Patient
Suppression of GATA factor activity causes axis duplication in Xenopus
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[Abstract] [PDF]

L. Gouedard, Y.-G. Chen, L. Thevenet, C. Racine, S. Borie, I. Lamarre, N. Josso, J. Massague, and N. di Clemente
Engagement of Bone Morphogenetic Protein Type IB Receptor and Smad1 Signaling by Anti-Mullerian Hormone and Its Type II Receptor
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[Abstract] [Full Text] [PDF]

X. Shi, S. Bai, L. Li, and X. Cao
Hoxa-9 R

				N. Shiraki, T. Yoshida, K. Araki, A. Umezawa, Y. Higuchi, H. Goto, K. Kume, and S. Kume Guided Differentiation of Embryonic Stem Cells into Pdx1-Expressing Regional-Specific Definitive Endoderm Stem Cells, April 1, 2008; 26(4): 874 - 885. [Abstract] [Full Text] [PDF]

				T. Suzuki, S. M. Hasso, and J. F. Fallon Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity PNAS, March 18, 2008; 105(11): 4185 - 4190. [Abstract] [Full Text] [PDF]

				R. V. Korupolu, U. Muenster, J. D. Read, W. Vale, and W. H. Fischer Activin A/Bone Morphogenetic Protein (BMP) Chimeras Exhibit BMP-like Activity and Antagonize Activin and Myostatin J. Biol. Chem., February 15, 2008; 283(7): 3782 - 3790. [Abstract] [Full Text] [PDF]

				K. B Lee, V. Khivansara, M. M Santos, P. Lamba, T. Yuen, S. C Sealfon, and D. J Bernard Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone {beta} subunit transcription J. Mol. Endocrinol., February 1, 2007; 38(2): 315 - 330. [Abstract] [Full Text] [PDF]

				L.-C. Yao, I. L. Blitz, D. A. Peiffer, S. Phin, Y. Wang, S. Ogata, K. W. Y. Cho, K. Arora, and R. Warrior Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism Development, October 15, 2006; 133(20): 4025 - 4034. [Abstract] [Full Text] [PDF]

				G. Ge and D. S. Greenspan BMP1 controls TGF{beta}1 activation via cleavage of latent TGF{beta}-binding protein J. Cell Biol., October 9, 2006; 175(1): 111 - 120. [Abstract] [Full Text] [PDF]

				A. Ishimura, J. K. Ng, M. Taira, S. G. Young, and S.-I. Osada Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor {beta} signaling Development, October 1, 2006; 133(19): 3919 - 3928. [Abstract] [Full Text] [PDF]

				P. G. Farnworth, P. G. Stanton, Y. Wang, R. Escalona, J. K. Findlay, and G. T. Ooi Inhibins Differentially Antagonize Activin and Bone Morphogenetic Protein Action in a Mouse Adrenocortical Cell Line Endocrinology, July 1, 2006; 147(7): 3462 - 3471. [Abstract] [Full Text] [PDF]

				S. Gupta, H. Zhu, L. I. Zon, and T. Evans BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis Development, June 1, 2006; 133(11): 2177 - 2187. [Abstract] [Full Text] [PDF]

				M. Poulain, M. Furthauer, B. Thisse, C. Thisse, and T. Lepage Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling Development, June 1, 2006; 133(11): 2189 - 2200. [Abstract] [Full Text] [PDF]

				M. Kluppel, T. N. Wight, C. Chan, A. Hinek, and J. L. Wrana Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis Development, September 1, 2005; 132(17): 3989 - 4003. [Abstract] [Full Text] [PDF]

				M. Ku, S. Y. Sokol, J. Wu, M. I. Tussie-Luna, A. L. Roy, and A. Hata Positive and Negative Regulation of the Transforming Growth Factor {beta}/Activin Target Gene goosecoid by the TFII-I Family of Transcription Factors Mol. Cell. Biol., August 15, 2005; 25(16): 7144 - 7157. [Abstract] [Full Text] [PDF]

				T. Alliston, T. C. Ko, Y. Cao, Y.-Y. Liang, X.-H. Feng, C. Chang, and R. Derynck Repression of Bone Morphogenetic Protein and Activin-inducible Transcription by Evi-1 J. Biol. Chem., June 24, 2005; 280(25): 24227 - 24237. [Abstract] [Full Text] [PDF]

				B. D. Cherrington, T. A. Farmerie, C. A. Lents, J. D. Cantlon, M. S. Roberson, and C. M. Clay Activin Responsiveness of the Murine Gonadotropin-Releasing Hormone Receptor Gene Is Mediated by a Composite Enhancer Containing Spatially Distinct Regulatory Elements Mol. Endocrinol., April 1, 2005; 19(4): 898 - 912. [Abstract] [Full Text] [PDF]

				A Pierre, C Pisselet, J Dupont, B Mandon-Pepin, D Monniaux, P Monget, and S Fabre Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells J. Mol. Endocrinol., December 1, 2004; 33(3): 805 - 817. [Abstract] [Full Text] [PDF]

				T. M. Doherty, L. A. Fitzpatrick, D. Inoue, J.-H. Qiao, M. C. Fishbein, R. C. Detrano, P. K. Shah, and T. B. Rajavashisth Molecular, Endocrine, and Genetic Mechanisms of Arterial Calcification Endocr. Rev., August 1, 2004; 25(4): 629 - 672. [Abstract] [Full Text] [PDF]

				B. Ohkawara, K. Shirakabe, J. Hyodo-Miura, R. Matsuo, N. Ueno, K. Matsumoto, and H. Shibuya Role of the TAK1-NLK-STAT3 pathway in TGF-{beta}-mediated mesoderm induction Genes & Dev., February 15, 2004; 18(4): 381 - 386. [Abstract] [Full Text] [PDF]

				E. Wiater and W. Vale Inhibin Is an Antagonist of Bone Morphogenetic Protein Signaling J. Biol. Chem., February 28, 2003; 278(10): 7934 - 7941. [Abstract] [Full Text] [PDF]

				R. K. Moore, F. Otsuka, and S. Shimasaki Molecular Basis of Bone Morphogenetic Protein-15 Signaling in Granulosa Cells J. Biol. Chem., January 3, 2003; 278(1): 304 - 310. [Abstract] [Full Text] [PDF]

				G. P. Raju, N. Dimova, P. S. Klein, and H.-C. Huang SANE, a Novel LEM Domain Protein, Regulates Bone Morphogenetic Protein Signaling through Interaction with Smad1 J. Biol. Chem., January 3, 2003; 278(1): 428 - 437. [Abstract] [Full Text] [PDF]

				E. C. Delot, M. E. Bahamonde, M. Zhao, and K. M. Lyons BMP signaling is required for septation of the outflow tract of the mammalian heart Development, January 1, 2003; 130(1): 209 - 220. [Abstract] [Full Text] [PDF]

				Y. Miyanaga, I. Torregroza, and T. Evans A Maternal Smad Protein Regulates Early Embryonic Apoptosis in Xenopus laevis Mol. Cell. Biol., March 1, 2002; 22(5): 1317 - 1328. [Abstract] [Full Text] [PDF]

				T. R. Clarke, Y. Hoshiya, S. E. Yi, X. Liu, K. M. Lyons, and P. K. Donahoe Mullerian Inhibiting Substance Signaling Uses a Bone Morphogenetic Protein (BMP)-Like Pathway Mediated by ALK2 and Induces Smad6 Expression Mol. Endocrinol., June 1, 2001; 15(6): 946 - 959. [Abstract] [Full Text] [PDF]

				M. E. Bahamonde and K. M Lyons BMP3: To Be or Not To Be a BMP J. Bone Joint Surg. Am., April 1, 2001; 83(90010): S56 - 62. [Abstract] [Full Text] [PDF]

				Y. Zhang, C. Chang, D. J. Gehling, A. Hemmati-Brivanlou, and R. Derynck Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase PNAS, January 30, 2001; 98(3): 974 - 979. [Abstract] [Full Text] [PDF]

				C. M. Ferguson, E. M. Schwarz, P. R. Reynolds, J. E. Puzas, R. N. Rosier, and R. J. O'Keefe Smad2 and 3 Mediate Transforming Growth Factor-{beta}1-Induced Inhibition of Chondrocyte Maturation Endocrinology, December 1, 2000; 141(12): 4728 - 4735. [Abstract] [Full Text] [PDF]

				I. Schwarte-Waldhoff, O. V. Volpert, N. P. Bouck, B. Sipos, S. A. Hahn, S. Klein-Scory, J. Luttges, G. Kloppel, U. Graeven, C. Eilert-Micus, et al. Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis PNAS, August 15, 2000; 97(17): 9624 - 9629. [Abstract] [Full Text] [PDF]

				R. H. Kim, D. Wang, M. Tsang, J. Martin, C. Huff, M. P. de Caestecker, W. T. Parks, X. Meng, R. J. Lechleider, T. Wang, et al. A novel Smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction Genes & Dev., July 1, 2000; 14(13): 1605 - 1616. [Abstract] [Full Text]

				S. Germain, M. Howell, G. M. Esslemont, and C. S. Hill Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif Genes & Dev., February 15, 2000; 14(4): 435 - 451. [Abstract] [Full Text]

				M. P. de Caestecker, T. Yahata, D. Wang, W. T. Parks, S. Huang, C. S. Hill, T. Shioda, A. B. Roberts, and R. J. Lechleider The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain J. Biol. Chem., January 21, 2000; 275(3): 2115 - 2122. [Abstract] [Full Text] [PDF]