The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Sonnenfeld, M.
	Articles by Crews, S.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Sonnenfeld, M.
	Articles by Crews, S.

Abbott, B. D., Birnbaum, L. S. and Perdew, G. H (1995). Developmental expression of two members of a new class of transcription factors: I. expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. Dev. Dyn 204, 133-143.[Medline]

Abbott, B. D. and Probst, M. R (1995). Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo. Dev. Dyn 204, 144-155.[Medline]

Boulianne, G. L., de la Concha, A., Campos-Ortega, J. A., Jan, L. Y. and Jan, Y. N (1991). The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J 10, 2975-2983.[Medline]

Chang, Z., Price, B. D., Bockheim, S., Boedigheimer, M. J., Smith, R. and Laughon, A (1993). Molecular and genetic characterization of the Drosophila tartan gene. Dev. Biol 160, 315-332.[Medline]

Dalby, B., Pereira, A. J. and Goldstein, L. S. B (1995). An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics 139, 757-766.[Abstract]

Franks, R. G. and Crews, S. T (1994). Transcriptional activation domains of the Single-minded bHLH protein are required for CNS midline cell development. Mech. Dev 45, 269-277.[Medline]

Frigerio, G., Burri, M., Bopp, D., Baumgartner, S. and Noll, M (1986). Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network. Cell 47, 735-746.[Medline]

Gradin, K., McGuire, J., Wenger, R. H., Kvietikova, I., Whitelaw, M. L., Toftgard, R., Tora, L., Gassmann, M. and Poellinger, L (1996). Functional interference between hypoxia and Dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol. Cell. Biol 16, 5221-5231.[Abstract]

Han, K., Levine, M. S. and Manley, J. L (1989). Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell 56, 573-583.[Medline]

Hankinson, O (1995). The Aryl hydrocarbon receptor complex. Ann. Rev. Pharmacol. Toxicol 35, 307-40.[Medline]

Hirose, K., Morita, M., Ema, M., Mimura, J., Hamada, H., Fujii, H., Saijo, Y., Gotoh, O., Sogawa, K. and Fujii-Kuriyama, Y (1996). cDNA cloning and tissue-specific expression of a novel basic-helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol. Cell. Bio.l 16, 1706-1713.[Abstract]

Hoffman, E. C., Reyes, H., Chu, F., Sander, F., Conley, L. H., Brooks, B. A. and Hankinson, O (1991). Cloning of a subunit of the DNA-binding form of the Ah (dioxin) receptor. Science 252, 954-958.[Abstract/Free Full Text]

Hogenesch, J. B., Chan, W. K., Kackiw, V. H., Brown, R. C., Gu, Y.-Z., Pray-Grant, M., Perdew, G. H. and Bradfield, C. A (1997). Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J. Biol. Chem 272, 8581-8593.[Abstract/Free Full Text]

Huang, Z. J., Edery, I. and Rosbash, M (1993). PAS is a dimerization domain common to Drosophila period and several transcription factors. Nature 364, 259-262.[Medline]

Isaac, D. D. and Andrew, D. J (1996). Tubulogenesis in Drosophila : a requirement for the trachealess gene product. Genes Dev 10, 103-117.[Abstract/Free Full Text]

Jain, S., Dolwick, K. M., Schmidt, J. V. and Bradfield, C. A (1994). Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxyl termini. J. Biol. Chem 269, 31518-31524.[Abstract/Free Full Text]

King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M.,Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., Turek, F. W. and Takahashi, J. S (1997). Positional cloning of the mouse circadian Clock gene. Cell 89, 641-653.[Medline]

Kl\212mbt, C., Glazer, L. and Shilo, B.-Z (1992). breathless , a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes Dev 6, 1668-1678.[Abstract/Free Full Text]

Kl\212mbt, C., Jacobs, J. R. and Goodman, C. S (1991). The midline of the Drosophila central nervous system: a model for the genetic analysis of cell fate, cell migration, and growth cone guidance. Cell 64, 801-815.[Medline]

Lewis, E. B. and Bacher, F (1968). Methods of feeding ethyl methane sulfonate (EMS) to Drosophila males. Drosophila Inf. Service 43, 193-.

Li, H., Dong, L. and Whitlock, J. P (1994). Transcriptional activation function of the mouse Ah receptor nuclear translocator. J. Biol. Chem 269, 28098-28105.[Abstract/Free Full Text]

Maltepe, E., Schmidt, J. V., Baunoch, D., Bradfield, C. A. and Simon, M. C (1997). Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386, 403-407.[Medline]

Mellerick, D. M. and Nirenberg, M (1995). Dorsal-ventral patterning genes restrict NK-2 homeobox gene expression to the ventral half of the central nervous system of Drosophila embryos. Dev. Biol 171, 306-316.[Medline]

Michaud, J. and Fan, C.-M (1997). Single-minded -two genes, three chromosomes. Genome Res 7, 569-571.[Free Full Text]

Mitchell, P. J. and Tjian, R (1989). Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245, 371-378.[Abstract/Free Full Text]

Nagao, M., Ebert, B. L., Ratcliffe, P. J. and Pugh, C. W (1996). Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-1 binding sites. FEBS Lett 387, 161-166.[Medline]

Nambu, J. R., Chen, W., Hu, S. and Crews, S. T (1996). The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human Hypoxia-inducible factor 1and Drosophila Single-minded. Gene 172, 249-254.[Medline]

Nambu, J. R., Franks, R. G., Hu, S. and Crews, S. T (1990). The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell 63, 63-75.[Medline]

Nambu, J. R., Lewis, J. L., Wharton, K. A. and Crews, S. T (1991). The Drosophila single-minded gene encodes a helix-loop-helix protein which acts as a master regulator of CNS midline development. Cell 67, 1157-1167.[Medline]

Patel, N. H., Snow, P. M. and Goodman, C. S (1987). Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell 48, 975-988.[Medline]

Pollenz, R. S., Sullivan, H. R., Holmes, J., Necela, B. and Peterson, R. E (1996). Isolation and expression of cDNAs from Rainbow Trout(Oncorhynchus mykiss) that encode two novel basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) proteins with distinct functions in the presence of the aryl hydrocarbon receptor. J. Biol. Chem 271, 30886-30896.[Abstract/Free Full Text]

Reisz-Porszasz, S., Probst, M. R., Fukunaga, B. N. and Hankinson, O (1994). Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT). Mol. Cell. Biol 14, 6075-6086.[Abstract/Free Full Text]

Sogawa, K. R., Nakano, A., Kobayashi, Y., Kikuchi, N., Ohe, N., Matsushita, N. and Fujii-Kuriyama, Y (1995). Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation. Proc. Nat. Acad. Sci USA 92, 1936-1940.[Abstract/Free Full Text]

Sonnenfeld, M. J. and Jacobs, J. R (1994). Mesectodermal cell fate analysis in Drosophila midline mutants. Mech. Dev 46, 3-13.[Medline]

Swanson, H. I., Chan, W. K. and Bradfield, C. A (1995). DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J. Biol. Chem 280, 26292-26302.

Thomas, J. B., Crews, S. T. and Goodman, C. S (1988). Molecular genetics of the single-minded locus: a gene involved in the development of the Drosophila nervous system. Cell 52, 133-141.[Medline]

Tian, H., McKnight, S. L. and Russell, D. W (1997). Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 11, 72-82.[Abstract/Free Full Text]

Tower, J., Karpen, G. H., Craig, N. and Spradling, A. C (1992). Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics 133, 347-359.[Abstract]

Wang, G. L., Jaing, B.-H., Rue, E. and Semenza, G. L (1995). Hypoxia-inducible factor 1 is a basic helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. USA 92, 5510-5514.[Abstract/Free Full Text]

Wharton, Jr, K. A. and Crews, S. T (1993). CNS midline enhancers of the Drosophila slit and Toll genes. Mech. Dev 40, 141-154.[Medline]

Wharton, Jr, K. A., Franks, R. G., Kasai, Y. and Crews, S. T (1994). Control of CNS midline transcription by asymmetric E-box elements: similarity to xenobiotic responsive regulation. Development 120, 3563-3569.[Abstract]

Wilk, R., Weizman, I., Glazer, L. and Shilo, B.-Z (1996). trachealess encodes a bHLH-PAS protein and is a master regulator gene in the Drosophila tracheal system. Genes Dev 10, 93-102.[Abstract/Free Full Text]

Xiao, H., Hrdlicka, L. A. and Nambu, J. R (1996). Alternate function of the single-minded and rhomboid genes in development of the Drosophila ventral neuroectoderm. Mech. Dev 58, 65-74.[Medline]

Younossi-Hartenstein, A. and Hartenstein, V (1993). The role of the tracheae and musculature during pathfinding of Drosophila embryonic sensory axons. Dev. Biol 158, 430-437.[Medline]

This article has been cited by other articles:

N. M. Romero, M. Irisarri, P. Roth, A. Cauerhff, C. Samakovlis, and P. Wappner
Regulation of the Drosophila Hypoxia-Inducible Factor {alpha} Sima by CRM1-Dependent Nuclear Export
Mol. Cell. Biol., May 15, 2008; 28(10): 3410 - 3423.
[Abstract] [Full Text] [PDF]

E. J. Dougherty and R. S. Pollenz
Analysis of Ah Receptor-ARNT and Ah Receptor-ARNT2 Complexes In Vitro and in Cell Culture
Toxicol. Sci., May 1, 2008; 103(1): 191 - 206.
[Abstract] [Full Text] [PDF]

P. Estes, E. Fulkerson, and Y. Zhang
Identification of Motifs That Are Conserved in 12 Drosophila Species and Regulate Midline Glia vs. Neuron Expression
Genetics, February 1, 2008; 178(2): 787 - 799.
[Abstract] [Full Text] [PDF]

D. Umetsu, S. Murakami, M. Sato, and T. Tabata
The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system
Development, March 1, 2006; 133(5): 791 - 800.
[Abstract] [Full Text] [PDF]

S. Herrmann, Q. Ma, M. S. Johnson, A. V. Repik, and B. L. Taylor
PAS Domain of the Aer Redox Sensor Requires C-Terminal Residues for Native-Fold Formation and Flavin Adenine Dinucleotide Binding
J. Bacteriol., October 15, 2004; 186(20): 6782 - 6791.
[Abstract] [Full Text] [PDF]

T. A. Gorr, J. D. Cahn, H. Yamagata, and H. F. Bunn
Hypoxia-induced Synthesis of Hemoglobin in the Crustacean Daphnia magna Is Hypoxia-inducible Factor-dependent
J. Biol. Chem., August 20, 2004; 279(34): 36038 - 36047.
[Abstract] [Full Text] [PDF]

T. A. Gorr, T. Tomita, P. Wappner, and H. F. Bunn
Regulation of Drosophila Hypoxia-inducible Factor (HIF) Activity in SL2 Cells: IDENTIFICATION OF A HYPOXIA-INDUCED VARIANT ISOFORM OF THE HIF{alpha} HOMOLOG GENE similar
J. Biol. Chem., August 20, 2004; 279(34): 36048 - 36058.
[Abstract] [Full Text] [PDF]

T. K. Smulders-Srinivasan and H. Lin
Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division
Genetics, December 1, 2003; 165(4): 1971 - 1991.
[Abstract] [Full Text] [PDF]

C. Liu, E. Goshu, A. Wells, and C.-M. Fan
Identification of the Downstream Targets of SIM1 and ARNT2, a Pair of Transcription Factors Essential for Neuroendocrine Cell Differentiation
J. Biol. Chem., November 7, 2003; 278(45): 44857 - 44867.
[Abstract] [Full Text] [PDF]

M. H. Aitola and M. T. Pelto-Huikko
Expression of Arnt and Arnt2 mRNA in Developing Murine Tissues
J. Histochem. Cytochem., January 1, 2003; 51(1): 41 - 54.
[Abstract] [Full Text] [PDF]

S. Lavista-Llanos, L. Centanin, M. Irisarri, D. M. Russo, J. M. Gleadle, S. N. Bocca, M. Muzzopappa, P. J. Ratcliffe, and P. Wappner
Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar
Mol. Cell. Biol., October 1, 2002; 22(19): 6842 - 6853.
[Abstract] [Full Text] [PDF]

E. Goshu, H. Jin, R. Fasnacht, M. Sepenski, J. L. Michaud, and C.-M. Fan
Sim2 Mutants Have Developmental Defects Not Overlapping with Those of Sim1 Mutants
Mol. Cell. Biol., June 15, 2002; 22(12): 4147 - 4157.
[Abstract] [Full Text] [PDF]

S. L. Woods and M. L. Whitelaw
Differential Activities of Murine Single Minded 1 (SIM1) and SIM2 on a Hypoxic Response Element. CROSS-TALK BETWEEN BASIC HELIX-LOOP-HELIX/Per-Arnt-Sim HOMOLOGY TRANSCRIPTION FACTORS
J. Biol. Chem., March 15, 2002; 277(12): 10236 - 10243.
[Abstract] [Full Text] [PDF]

J. P. H. Burbach, S. M. Luckman, D. Murphy, and H. Gainer
Gene Regulation in the Magnocellular Hypothalamo-Neurohypophysial System
Physiol Rev, July 1, 2001; 81(3): 1197 - 1267.
[Abstract] [Full Text] [PDF]

W. V. So, L. Sarov-Blat, C. K. Kotarski, M. J. McDonald, R. Allada, and M. Rosbash
takeout, a Novel Drosophila Gene under Circadian Clock Transcriptional Regulation
Mol. Cell. Biol., September 15, 2000; 20(18): 6935 - 6944.
[Abstract] [Full Text]

Y. Ma, K. Certel, Y. Gao, E. Niemitz, J. Mosher, A. Mukherjee, M. Mutsuddi, N. Huseinovic, S. T. Crews, W. A. Johnson, et al.
Functional Interactions between Drosophila bHLH/PAS, Sox, and POU Transcription Factors Regulate CNS Midline Expression of the slit Gene
J. Neurosci., June 15, 2000; 20(12): 4596 - 4605.
[Abstract] [Full Text] [PDF]

M. J. Lees and M. L. Whitelaw
Multiple Roles of Ligand in Transforming the Dioxin Receptor to an Active Basic Helix-Loop-Helix/PAS Transcription Factor Complex with the Nuclear Protein Arnt
Mol. Cell. Biol., August 1, 1999; 19(8): 5811 - 5822.
[Abstract] [Full Text] [PDF]

R. J. Metzger and M. A. Krasnow
Genetic Control of Branching Morphogenesis
Science, June 4, 1999; 284(5420): 1635 - 1639.
[Abstract] [Full Text]

H. Hao, N. R.�J. Glossop, L. Lyons, J. Qiu, B. Morrish, Y. Cheng, C. Helfrich-Forster, and P. Hardin
The 69�bp Circadian Regulatory Sequence (CRS) Mediates per-Like Developmental, Spatial, and Circadian Expression and Behavioral Rescue in Drosophila
J. Neurosci., February 1, 1999; 19(3): 987 - 994.
[Abstract] [Full Text] [PDF]

N. Gekakis, D. Staknis, H. B. Nguyen, F. C. Davis, L. D. Wilsbacher, D. P. King, J. S. Takahashi, and C. J. Weitz
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
Science, June 5, 1998; 280(5369): 1564 - 1569.
[Abstract] [Full Text]

J.-L. Pellequer, K. A. Wager-Smith, S. A. Kay, and E. D. Getzoff
Photoactive yellow protein: A structural prototype for the three-dimensional fold of the PAS domain superfamily
PNAS, May 26, 1998; 95(11): 5884 - 5890.
[Abstract] [Full Text] [PDF]

N. W. Chong, M. Bernard, and D. C. Klein
Characterization of the Chicken Serotonin N-Acetyltransferase Gene. ACTIVATION VIA CLOCK GENE HETERODIMER/E BOX INTERACTION
J. Biol. Chem., October 13, 2000; 275(42): 32991 - 32998.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Sonnenfeld, M.

Articles by Crews, S.

Search for Related Content

PubMed

PubMed Citation

Articles by Sonnenfeld, M.

Articles by Crews, S.

				E. J. Dougherty and R. S. Pollenz Analysis of Ah Receptor-ARNT and Ah Receptor-ARNT2 Complexes In Vitro and in Cell Culture Toxicol. Sci., May 1, 2008; 103(1): 191 - 206. [Abstract] [Full Text] [PDF]

				P. Estes, E. Fulkerson, and Y. Zhang Identification of Motifs That Are Conserved in 12 Drosophila Species and Regulate Midline Glia vs. Neuron Expression Genetics, February 1, 2008; 178(2): 787 - 799. [Abstract] [Full Text] [PDF]

				D. Umetsu, S. Murakami, M. Sato, and T. Tabata The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system Development, March 1, 2006; 133(5): 791 - 800. [Abstract] [Full Text] [PDF]

				S. Herrmann, Q. Ma, M. S. Johnson, A. V. Repik, and B. L. Taylor PAS Domain of the Aer Redox Sensor Requires C-Terminal Residues for Native-Fold Formation and Flavin Adenine Dinucleotide Binding J. Bacteriol., October 15, 2004; 186(20): 6782 - 6791. [Abstract] [Full Text] [PDF]

				T. A. Gorr, J. D. Cahn, H. Yamagata, and H. F. Bunn Hypoxia-induced Synthesis of Hemoglobin in the Crustacean Daphnia magna Is Hypoxia-inducible Factor-dependent J. Biol. Chem., August 20, 2004; 279(34): 36038 - 36047. [Abstract] [Full Text] [PDF]

				T. A. Gorr, T. Tomita, P. Wappner, and H. F. Bunn Regulation of Drosophila Hypoxia-inducible Factor (HIF) Activity in SL2 Cells: IDENTIFICATION OF A HYPOXIA-INDUCED VARIANT ISOFORM OF THE HIF{alpha} HOMOLOG GENE similar J. Biol. Chem., August 20, 2004; 279(34): 36048 - 36058. [Abstract] [Full Text] [PDF]

				T. K. Smulders-Srinivasan and H. Lin Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division Genetics, December 1, 2003; 165(4): 1971 - 1991. [Abstract] [Full Text] [PDF]

				C. Liu, E. Goshu, A. Wells, and C.-M. Fan Identification of the Downstream Targets of SIM1 and ARNT2, a Pair of Transcription Factors Essential for Neuroendocrine Cell Differentiation J. Biol. Chem., November 7, 2003; 278(45): 44857 - 44867. [Abstract] [Full Text] [PDF]

				M. H. Aitola and M. T. Pelto-Huikko Expression of Arnt and Arnt2 mRNA in Developing Murine Tissues J. Histochem. Cytochem., January 1, 2003; 51(1): 41 - 54. [Abstract] [Full Text] [PDF]

				S. Lavista-Llanos, L. Centanin, M. Irisarri, D. M. Russo, J. M. Gleadle, S. N. Bocca, M. Muzzopappa, P. J. Ratcliffe, and P. Wappner Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar Mol. Cell. Biol., October 1, 2002; 22(19): 6842 - 6853. [Abstract] [Full Text] [PDF]

				E. Goshu, H. Jin, R. Fasnacht, M. Sepenski, J. L. Michaud, and C.-M. Fan Sim2 Mutants Have Developmental Defects Not Overlapping with Those of Sim1 Mutants Mol. Cell. Biol., June 15, 2002; 22(12): 4147 - 4157. [Abstract] [Full Text] [PDF]

				S. L. Woods and M. L. Whitelaw Differential Activities of Murine Single Minded 1 (SIM1) and SIM2 on a Hypoxic Response Element. CROSS-TALK BETWEEN BASIC HELIX-LOOP-HELIX/Per-Arnt-Sim HOMOLOGY TRANSCRIPTION FACTORS J. Biol. Chem., March 15, 2002; 277(12): 10236 - 10243. [Abstract] [Full Text] [PDF]

				J. P. H. Burbach, S. M. Luckman, D. Murphy, and H. Gainer Gene Regulation in the Magnocellular Hypothalamo-Neurohypophysial System Physiol Rev, July 1, 2001; 81(3): 1197 - 1267. [Abstract] [Full Text] [PDF]

				W. V. So, L. Sarov-Blat, C. K. Kotarski, M. J. McDonald, R. Allada, and M. Rosbash takeout, a Novel Drosophila Gene under Circadian Clock Transcriptional Regulation Mol. Cell. Biol., September 15, 2000; 20(18): 6935 - 6944. [Abstract] [Full Text]

				Y. Ma, K. Certel, Y. Gao, E. Niemitz, J. Mosher, A. Mukherjee, M. Mutsuddi, N. Huseinovic, S. T. Crews, W. A. Johnson, et al. Functional Interactions between Drosophila bHLH/PAS, Sox, and POU Transcription Factors Regulate CNS Midline Expression of the slit Gene J. Neurosci., June 15, 2000; 20(12): 4596 - 4605. [Abstract] [Full Text] [PDF]

				M. J. Lees and M. L. Whitelaw Multiple Roles of Ligand in Transforming the Dioxin Receptor to an Active Basic Helix-Loop-Helix/PAS Transcription Factor Complex with the Nuclear Protein Arnt Mol. Cell. Biol., August 1, 1999; 19(8): 5811 - 5822. [Abstract] [Full Text] [PDF]

				R. J. Metzger and M. A. Krasnow Genetic Control of Branching Morphogenesis Science, June 4, 1999; 284(5420): 1635 - 1639. [Abstract] [Full Text]

				H. Hao, N. R.�J. Glossop, L. Lyons, J. Qiu, B. Morrish, Y. Cheng, C. Helfrich-Forster, and P. Hardin The 69�bp Circadian Regulatory Sequence (CRS) Mediates per-Like Developmental, Spatial, and Circadian Expression and Behavioral Rescue in Drosophila J. Neurosci., February 1, 1999; 19(3): 987 - 994. [Abstract] [Full Text] [PDF]

				N. Gekakis, D. Staknis, H. B. Nguyen, F. C. Davis, L. D. Wilsbacher, D. P. King, J. S. Takahashi, and C. J. Weitz Role of the CLOCK Protein in the Mammalian Circadian Mechanism Science, June 5, 1998; 280(5369): 1564 - 1569. [Abstract] [Full Text]

				J.-L. Pellequer, K. A. Wager-Smith, S. A. Kay, and E. D. Getzoff Photoactive yellow protein: A structural prototype for the three-dimensional fold of the PAS domain superfamily PNAS, May 26, 1998; 95(11): 5884 - 5890. [Abstract] [Full Text] [PDF]

				N. W. Chong, M. Bernard, and D. C. Klein Characterization of the Chicken Serotonin N-Acetyltransferase Gene. ACTIVATION VIA CLOCK GENE HETERODIMER/E BOX INTERACTION J. Biol. Chem., October 13, 2000; 275(42): 32991 - 32998. [Abstract] [Full Text] [PDF]