Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Percival-Smith, A.
	Articles by Wilson, P.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Percival-Smith, A.
	Articles by Wilson, P.

Aspland, S. E. and White, R. A. H (1997). Nucleocytoplasmic localisation of extradenticle protein is spatially regulated throughout development in Drosophila. Development 124, 741-747.[Abstract]

Basler, K. and Struhl, G (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.[Medline]

Capovilla, M., Brandt, M. and Botas, J (1994). Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76, 461-475.[Medline]

Carroll, S. B (1995). Homeotic genes and the evolution of arthopods and chordates. Nature 376, 479-485.[Medline]

Castelli-Gair, J. and Akam, M (1995). How the Hox gene Utrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres. Development 121, 2973-2982.[Abstract]

Chadwick, R. and McGinnis, W (1987). Temporal and spacial distribution of transcripts from the Deformed gene of Drosophila. EMBO J 6, 779-789.[Medline]

Chan, S-K. and Mann R. S (1993). The segment identity functions of Ultrabithorax are contained within its homeodomain and carboxy-terminal sequences. Genes and Dev 7, 796-811.[Abstract/Free Full Text]

Chan, S-K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S (1994). The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with Extradenticle, another Homeoprotein. Cell 78, 803-813.

Chan, S-K., P\232pperl, H., Krumlauf, R. and Mann R. S (1996). An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J 15, 2476-2487.[Medline]

Cribbs, D. L., Pultz, M. A., Johnson, D., Mazzulla, M. and Kaufman, T. C (1992). Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia. EMBO J 11, 1437-1449.[Medline]

Cribbs, D. L., Benassayag, C., Randazzo, F. M. and Kaufman, T. C (1995). Levels of homeotic protein function can determine developmental identity: evidence from low-level expression of the Drosophila homeotic gene proboscipedia under Hsp70 control. EMBO J 14, 767-778.[Medline]

Currie, D. and Bate, M (1991). Development of adult abdominal muscles in Drosophila: Adult myoblasts express twist and are associated with nerves. Development 113, 91-102.[Abstract]

Dranginis, A. M (1990). Binding of yeast a1 and2 as a heterodimer to the operator DNA of a haploid-specific gene. Nature 347, 682-685.[Medline]

Furukubo-Tokunaga, K. Flister, S. and Gehring, W. J (1993). Functional specificity of the Antennapedia homeodomain. Proc. Natl. Acad. Sci. USA 90, 6360-6464.[Abstract/Free Full Text]

Gehring, W. J., Qian, Y. Q., Billeter, M., Furukubo-Tokunaga, K., Schier, A. F., Resendez-Perez, D., Affolter, M. and Wuthrich, K (1994). Homeodomain-DNA recognition. Cell 78, 211-223.[Medline]

Gibson, G., Schier, A. F., LeMotte, P. and Gehring, W. J (1990). The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell 62, 1087-1103.[Medline]

Glickman, M. A. and Brower, D. L (1988). Expression of Sex combs reduced protein in Drosophila larvae. Dev. Biol 127, 113-118.[Medline]

Golic, K. G (1991). Site-specific recombination between homologous chromosomes in Drosophila. Science 252, 958-961.[Abstract/Free Full Text]

Gonzalez-Crespo, S. and Morata, G (1996). Genetic evidence for the subdivision of the arthropod limb into coxopodite and telopodite. Development 122, 3921-3928.[Abstract]

Hall, M. N. and Johnson, A. D (1987). Homeodomain of the yeast repressor2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science 237, 1007-1012.[Abstract/Free Full Text]

Hanes, S. D. and Brent, R (1991). A genetic model for interaction of the Homeodomain recognition helix with DNA. Science 251, 426-430.[Abstract/Free Full Text]

Herskowitz, I (1987). Functional inactivation of genes by dominant negative mutations. Nature 329, 219-222.[Medline]

Herskowitz, I (1989). A regulatory hierarchy for cell specialization in yeast. Nature 342, 749-757.[Medline]

Hill, R. J. and Sternberg, P. W (1992). The gene lin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358, 470-476.[Medline]

Hunt, P. and Krumlauf, R (1991). Deciphering the Hox code: Clues to patterning brachial regions of the head. Cell 66, 1075-1078.[Medline]

Immergluck, K., Lawrence, P. A. and Bienz, M (1990). Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62, 261-268.[Medline]

Johnson, F. B., Parker, E. and Krasnow, M. A (1995). Extradenticle protein is a selective cofactor for the Drosophila homeotics: Role of the homeodomain and YPWM amino acid motif in the interaction. Proc. Natl. Acad. Sci. USA 92, 739-743.[Abstract/Free Full Text]

Kaufman, T. C (1978). Cytogenetic analysis of chromosome 3 in Drosophila melanogaster : isolation and characterization of four new alleles of proboscipedia ( pb ) locus. Genetics 90, 579-596.[Abstract/Free Full Text]

Klemenz, R., Weber, U. and Gehring, W. J (1987). The white gene as a marker in a new P-elemnt vector for gene transfer in Drosophila. NAR 10, 3947-3959.

Kuroiwa, A., Kloter, U., Baumgartner, P. and Gehring, W. J (1985). Cloning of the homeotic Sex combs reduced gene in Drosophila and in situ localization of its transcripts. EMBO J 4, 3757-3764.[Medline]

LeMotte, P. K., Kuroiwa, A., Fessler, L. I. and Gehring, W. J (1989). The homeotic gene Sex combs reduced of Drosophila : gene structure and embryonic expression. EMBO J 8, 219-227.[Medline]

Lewis, E. B (1978). A gene complex controlling segmentation in Drosophila. Nature 276, 565-570.[Medline]

Li, T., Stark, M. R., Johnson, A. D. and Wolberger, C (1995). Crystal structure of the MATa1/MAT2 homeodomain heterodimer bound to DNA. Science 270, 262-269.[Abstract/Free Full Text]

Mahaffey, J. and Kaufman, T. C (1987). Distribution of the Sex combs reduced gene products in Drosophila melanogaster. Genetics 117, 51-60.[Abstract/Free Full Text]

Mann, R. S. and Hogness, D. S (1990). Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell 60, 597-610.[Medline]

McGinnis, W. and Krumlauf, R (1992). Homeobox genes and axial patterning. Cell 68, 283-302.[Medline]

Padgett, R. W., St Johnston, D. and Gelbart, W. M (1987). A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family. Nature 325, 81-84.[Medline]

Panzer, S., Weigel, D. and Beckendorf, S. K (1992). Organogenesis in Drosophila melanogaster: embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes. Development 114, 49-57.[Abstract]

Pattatucci, A. and Kaufman, T. C (1991). The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development. Genetics 129, 443-461.[Abstract]

Pattatucci, A. M., Otteson, D. C. and Kaufman, T. C (1991). A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster. Genetics 129, 423-441.[Abstract]

Pederson, J. D., Kiehart, D. P. and Mahaffey, J. W (1996). The role of HOM-C genes in segmental transformations: Reexamination of the Drosophila Sex combs reduced embryonic phenotype. Dev. Biol 180, 131-142.[Medline]

Peifer, M., Karch, F. and Bender, W (1987). The bithorax complex: control of segmental identity. Genes and Dev 1, 891-898.[Free Full Text]

Peifer, M. and Wieschaus, E (1990). Mutations in the Drosophila gene extradenticle affect the way specific homeodomain proteins regulate segmental identity. Genes and Dev 4, 1209-1223.[Abstract/Free Full Text]

Percival-Smith, A., Muller, M., Affolter, M. and Gehring, W. J (1990). The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. EMBO J 9, 3967-3974.[Medline]

Pultz, M. A., Diederich, R. J., Cribbs, D. L. and Kaufman, T. C (1988). The proboscipedia locus of the Antennapedia Complex: a molecular and genetic analysis. Genes and Dev 2, 901-920.[Abstract/Free Full Text]

Randazzo, F. M., Cribbs, D. L. and Kaufman, T. C (1991). Rescue and regulation of proboscipedia : a homeotic gene of the Antennapedia complex. Development 113, 257-271.[Abstract]

Rauskolb, C., Peifer, M. and Wieschaus, E (1993). extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing, Human proto-oncogene pbx1. Cell 74, 1101-1112.[Medline]

Reuter, R. and Scott, M. P (1990). Expression and function of the homeotic genes Antennapedia and Sex combs reduced in embryonic midgut of Drosophila. Development 109, 289-303.[Abstract]

Rubin, G. M. and Spradling, A. C (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.[Abstract/Free Full Text]

Salser, S. J. and Kenyon, C (1996). A C. elegans Hox gene switches on, off, on, and off again to regulate proliferation, differentiation, and morphogenesis. Development 122, 1651-1661.[Abstract]

Schier, A. F. and Gehring, W. J (1992). Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature 356, 804-807.[Medline]

Schneuwly, S., Klemenz, R. and Gehring, W. J (1987). Redesigning the body plan of Drosophila by ectopic expression of the homeotic gene Antennapedia. Nature 235, 816-818.

Slack, J. M. W., Holland, P. W. H. and Graham, C. F (1993). The Zootype and the Phylotypic Stage. Nature 361, 490-492.[Medline]

Struhl, G (1981). A homeotic mutation transforming leg to antenna in Drosophila. Nature 292, 635-638.[Medline]

Struhl, G (1981). Anterior and posterior compartments in the proboscis of Drosophila. Dev. Biol 84, 372-385.

Struhl, G (1982). Genes controlling segmental specification in the Drosophila thorax. Proc. Natl. Acad. Sci. USA 79, 7380-7384.[Abstract/Free Full Text]

Struhl, G (1983). Role of the esc +gene product in ensuring the selective expression of segment-specific homeotic genes in Drosophila. J. Embryol. exp. Morph 76, 297-331.[Medline]

Struhl, G. and Basler, K (1993). Organizing activity of wingless protein in Drosophila. Cell 72, 527-540.[Medline]

Tautz, D. and Pfeifle, C (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.[Medline]

Villee, C. A (1944). Phenogenetic studies of the homoeotic mutants of Drosophila melanogaster II. The effects of temperature on expression of proboscipedia. J. Exp. Biol 96, 85-102.

Xu, T. and Rubin, G. M (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.[Abstract]

Zecca, M., Basler, K.,and Struhl, G (1995). Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.[Abstract]

Zeng, W., Andrews, D. J., Mathies, L. D., Horner, M. A. and Scott, M.P (1993). Ectopic expression and function of the Antp and Scr homeotic genes; the N terminus of the homeodomain is critical to functional specificity. Development 118, 339-352.[Abstract]

This article has been cited by other articles:

J. Anderson, R. Bhandari, and J. P. Kumar
A Genetic Screen Identifies Putative Targets and Binding Partners of CREB-Binding Protein in the Developing Drosophila Eye
Genetics, December 1, 2005; 171(4): 1655 - 1672.
[Abstract] [Full Text] [PDF]

C. Benassayag, S. Plaza, P. Callaerts, J. Clements, Y. Romeo, W. J. Gehring, and D. L. Cribbs
Evidence for a direct functional antagonism of the selector genes proboscipedia and eyeless in Drosophila head development
Development, February 1, 2003; 130(3): 575 - 586.
[Abstract] [Full Text] [PDF]

M. A. DeCamillis, D. L. Lewis, S. J. Brown, R. W. Beeman, and R. E. Denell
Interactions of the Tribolium Sex combs reduced and proboscipedia Orthologs in Embryonic Labial Development
Genetics, December 1, 2001; 159(4): 1643 - 1648.
[Abstract] [Full Text] [PDF]

A. Abzhanov, S. Holtzman, and T. C. Kaufman
The Drosophila proboscis is specified by two Hox genes, proboscipedia and Sex combs reduced, via repression of leg and antennal appendage genes
Development, July 15, 2001; 128(14): 2803 - 2814.
[Abstract] [Full Text] [PDF]

M. Saleh, I. Rambaldi, X.-J. Yang, and M. S. Featherstone
Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases
Mol. Cell. Biol., November 15, 2000; 20(22): 8623 - 8633.
[Abstract] [Full Text]

M. Boube, C. Faucher, L. Joulia, D. L. Cribbs, and H.-M. Bourbon
Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification
Genes & Dev., November 15, 2000; 14(22): 2906 - 2917.
[Abstract] [Full Text]

T. D. Shippy, J. Guo, S. J. Brown, R. W. Beeman, and R. E. Denell
Analysis of maxillopedia Expression Pattern and Larval Cuticular Phenotype in Wild-Type and Mutant Tribolium
Genetics, June 1, 2000; 155(2): 721 - 731.
[Abstract] [Full Text]

C. Hughes and T. Kaufman
RNAi analysis of Deformed, proboscipedia and Sex combs reduced in the milkweed bug Oncopeltus fasciatus: novel roles for Hox genes in the hemipteran head
Development, January 9, 2000; 127(17): 3683 - 3694.
[Abstract] [PDF]

H. D. Ryoo and R. S. Mann
The control of trunk Hox specificity and activity by Extradenticle
Genes & Dev., July 1, 1999; 13(13): 1704 - 1716.
[Abstract] [Full Text]

T. R. Breen
Mutant Alleles of the Drosophila trithorax Gene Produce Common and Unusual Homeotic and Other Developmental Phenotypes
Genetics, May 1, 1999; 152(1): 319 - 344.
[Abstract] [Full Text]

A. Percival-Smith and D. J. Hayden
Analysis in Drosophila melanogaster of the Interaction Between Sex Combs Reduced and Extradenticle Activity in the Determination of Tarsus and Arista Identity
Genetics, September 1, 1998; 150(1): 189 - 198.
[Abstract] [Full Text]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Percival-Smith, A.

Articles by Wilson, P.

Search for Related Content

PubMed

PubMed Citation

Articles by Percival-Smith, A.

Articles by Wilson, P.

				C. Benassayag, S. Plaza, P. Callaerts, J. Clements, Y. Romeo, W. J. Gehring, and D. L. Cribbs Evidence for a direct functional antagonism of the selector genes proboscipedia and eyeless in Drosophila head development Development, February 1, 2003; 130(3): 575 - 586. [Abstract] [Full Text] [PDF]

				M. A. DeCamillis, D. L. Lewis, S. J. Brown, R. W. Beeman, and R. E. Denell Interactions of the Tribolium Sex combs reduced and proboscipedia Orthologs in Embryonic Labial Development Genetics, December 1, 2001; 159(4): 1643 - 1648. [Abstract] [Full Text] [PDF]

				A. Abzhanov, S. Holtzman, and T. C. Kaufman The Drosophila proboscis is specified by two Hox genes, proboscipedia and Sex combs reduced, via repression of leg and antennal appendage genes Development, July 15, 2001; 128(14): 2803 - 2814. [Abstract] [Full Text] [PDF]

				M. Saleh, I. Rambaldi, X.-J. Yang, and M. S. Featherstone Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases Mol. Cell. Biol., November 15, 2000; 20(22): 8623 - 8633. [Abstract] [Full Text]

				M. Boube, C. Faucher, L. Joulia, D. L. Cribbs, and H.-M. Bourbon Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification Genes & Dev., November 15, 2000; 14(22): 2906 - 2917. [Abstract] [Full Text]

				T. D. Shippy, J. Guo, S. J. Brown, R. W. Beeman, and R. E. Denell Analysis of maxillopedia Expression Pattern and Larval Cuticular Phenotype in Wild-Type and Mutant Tribolium Genetics, June 1, 2000; 155(2): 721 - 731. [Abstract] [Full Text]

				C. Hughes and T. Kaufman RNAi analysis of Deformed, proboscipedia and Sex combs reduced in the milkweed bug Oncopeltus fasciatus: novel roles for Hox genes in the hemipteran head Development, January 9, 2000; 127(17): 3683 - 3694. [Abstract] [PDF]

				H. D. Ryoo and R. S. Mann The control of trunk Hox specificity and activity by Extradenticle Genes & Dev., July 1, 1999; 13(13): 1704 - 1716. [Abstract] [Full Text]

				T. R. Breen Mutant Alleles of the Drosophila trithorax Gene Produce Common and Unusual Homeotic and Other Developmental Phenotypes Genetics, May 1, 1999; 152(1): 319 - 344. [Abstract] [Full Text]

				A. Percival-Smith and D. J. Hayden Analysis in Drosophila melanogaster of the Interaction Between Sex Combs Reduced and Extradenticle Activity in the Determination of Tarsus and Arista Identity Genetics, September 1, 1998; 150(1): 189 - 198. [Abstract] [Full Text]