Bax promotes neuronal cell death and is downregulated during the development of the nervous system

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Allsopp, T. E., Wyatt, S., Paterson, H. F. and Davies, A. M (1993). The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73, 295-307.[Medline]

Alnemri, E. S., Livingston, D. J., Nicholson, D. W., Salvesen, G., Thornberry, N. A., Wong, W. W. and Yuan, J (1996). Human ICE/CED-3 protease nomenclature. Cell 87, 171-.[Medline]

Barde, Y.-A (1989). Trophic factors and neuronal survival. Neuron 2, 1525-1534.[Medline]

Blaschke, A. J., Staley, K. and Chun, J (1996). Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex. Development 122, 1165-1174.[Abstract]

Boise, L. H., Gonz\207lez-Garcia, M., Postema, C. E., Ding, L., Lindsten, T., Turka, L. A., Mao, X., Nu\226ez, G. and Thompson, C. B (1993). bcl-x , a bcl-2 -related gene that functions as a dominant regulator of apoptotic cell death. Cell 74, 597-608.[Medline]

Bump, N. J., Hackett, M., Hugunin, M., Seshagiri, S., Brady, K., Chen, P., Ferenz, C., Franklin, S., Ghayur, T., Li, P., Licari, P., Mankovich, J., Shi, L., Greenberg, A. H., Miller, L. K. and Wong, W. W (1995). Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science 269, 1885-1888.[Abstract/Free Full Text]

Cheng, E. H.-Y., Levine, B., Boise, L. H., Thompson, C. B. and Hardwick, J. M (1996). Bax-independent inhibition of apoptosis by Bcl-xL. Nature 379, 554-556.[Medline]

Chinnaiyan, A. M., Orth, K., O'Rourke, K., Duan, H., Poirer, G. G. and Dixit, V. M (1996). Molecular ordering of the cell death pathway. J. Biol. Chem 271, 4573-4576.[Abstract/Free Full Text]

Cleary, M. L. and Sklar, J (1985). Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc. Natl. Acad. Sci. USA 82, 7439-7443.[Abstract/Free Full Text]

Davies, A. M (1995). The Bcl-2 family of proteins, and the regulation of neuronal survival. Trends Neurosci 18, 355-358.[Medline]

Deckwerth, T. L., Elliott, J. L., Knudson, C. M., Johnson, E. M., Snider, W. D. and Korsmeyer, S. J (1996). Bax is required for neuronal death after trophic factor deprivation and during development. Neuron 17, 401-411.[Medline]

Doherty, P., Mann, D. A. and Walsh, F. S (1988). Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures. J. Cell. Biol 107, 333-340.[Abstract/Free Full Text]

Ellis, R. E., Yuan, J. and Horvitz, H. R (1991). Mechanisms and functions of cell death. Annu. Rev. Cell Biol 7, 663-698.

Farrow, S. N., White, J. H. M., Martinou, I., Raven, T., Pun, K.-T.,Grinham, C. J., Martinou, J. C. and Brown, R (1995). Cloning of a bcl-2 homologue by interaction with adenovirus E1B19K. Nature 374, 731-733.[Medline]

Gagliardini, V., Fernandez, P.-A., Lee, R. K. K., Drexler, H. C. A., Rotello, R. J., Fishman, M. C. and Yuan, J (1994). Prevention of vertebrate neuronal death by the crmA gene. Science 263, 826-828.[Abstract/Free Full Text]

Garcia, I., Martinou, I., Tsujimoto, Y. and Martinou, J.-C (1992). Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-304.[Abstract/Free Full Text]

Gonzalez-Garcia, M., Perez-Ballestero, R., Ding, L., Duan, L., Boise, L. H., Thompson, C. B. and Nu\226ez, G (1994). bcl-xL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 120, 3033-3042.[Abstract]

Gonzalez-Garcia, M., Garcia, I., Ding, L., O'Shea, S., Boise, L.H., Thompson, C. B. and Nunez, G (1995). bcl-x is expressed in embryonic and postnatal tissues and functions to prevent neuronal cell death. Proc. Natl. Acad. Sci. USA 92, 4304-4308.[Abstract/Free Full Text]

Greene, L. A. and Tischler, A. S (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.[Abstract/Free Full Text]

Greenlund, L. J. S., Korsmeyer, S. J. and Johnson, E. M (1995). Role of Bcl-2 in the survival and function of developing and mature sympathetic neurons. Neuron 15, 649-661.[Medline]

Ham, J., Babij, C., Whitfield, J., Pfarr, C. M., Lallemand, D., Yaniv, M. and Rubin, L. L (1995). A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14, 927-939.[Medline]

Hatten, M. E. and Heintz, N (1995). Mechanisms of neural patterning and specification in the developing cerebellum. Annu. Rev. Neurosci 18, 385-408.[Medline]

Hayes, T. E., Valtz, N. L. M. and McKay, R. D. G (1991). Downregulation of CDC2 upon terminal differentiation of neurons. New Biol 3, 259-269.[Medline]

Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M. and Korsmeyer, S. J (1991). Bcl-2 protein is topographically restricted in tissues characterised by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88, 6961-6965.[Abstract/Free Full Text]

Korsmeyer, S. J (1995). Regulators of cell death. Trends Genet 11, 101-105.[Medline]

Korsmeyer, S. J., Shutter, J. R., Veis, D. J., Merry, D. E. and Oltvai, Z. N (1993). Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Cancer Biol 4, 327-332.

Krajewski, S., Krajewska, M., Shabaik, A., Miyashita, T., Wang, H. G. and Reed, J. C (1994). Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Amer. J. Pathol 145, 1323-1336.[Abstract]

Krajewski, S., Mai, J. K., Krajewska, M., Sikorska, M., Mossakowski, M. J. and Reed, J. C (1995). Upregulation of Bax protein levels in neurons following cerebral ischemia. J. Neurosci 15, 6364-6376.[Abstract/Free Full Text]

Levi-Montalcini, R (1987). The nerve growth factor 35 years later. Science 237, 1154-1162.[Free Full Text]

Martinou, I., Fernandez, P.-A., Missotten, M., White, E., Allet, B., Sadout, R. and Martinou, J.-C (1995). Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation. J. Cell. Biol 128, 201-208.[Abstract/Free Full Text]

Mason, C.A., Christakos, S. and Catalano, S.M (1990). Early climbing fiber interactions with Purkinje cells in the postnatal mouse cerebellum. J. Comp. Neurol 297, 77-90.[Medline]

Merry, D. E., Veis, D. J., Hickey, W. F. and Korsmeyer, S. J (1994). Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development 120, 301-311.[Abstract]

Michaelidis, T.M., Sendtner, M., Cooper, J.D., Airaksinen, M.S., Holtmann, B., Meyer, M. and Thoenen, H (1996). Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 17, 75-89.[Medline]

Middleton, G., Nu\226ez, G. and Davies, A. M (1996). Bax promotes neuronal survival and antagonizes the survival effects of neurotrophic factors. Development 122, 695-701.[Abstract]

Milligan, C. E., Prevette, D., Yaginuma, H., Homma, S., Cardwell, C., Fritz, L. C., Tomaselli, K. J., Oppenheim, R. W. and Schwartz, L. M (1995). Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron 15, 385-393.[Medline]

Miyashita, T. and Reed, J. C (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.[Medline]

Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B. and Reed, J. C (1994). Tumor suppressorp53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9, 1799-1805.[Medline]

Motoyama, N., Wang, F., Roth, K. A., Sawa, H., Nakayama, K.-I., Nakayama, K., Negishi, I., Senju, S., Zhang, Q., Fuji, S. and Loh, D. Y (1995). Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267, 1506-1510.[Abstract/Free Full Text]

Nakayama, K.-I., Nakayama, K., Negishi, I., Kuida, K., Shinkai, Y., Louie, M. C., Fields, L. E., Lucas, P. J., Stewart, V., Alt, F. W. and Loh, D. Y (1993). Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 261, 1584-1588.[Abstract/Free Full Text]

Oltvai, Z. N., Milliman, C. L. and Korsmeyer, S. J (1993). Bcl-2 heterodimerizes with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.[Medline]

Raff, M. C (1992). Social controls on cell survival and cell death. Nature 356, 397-400.[Medline]

Raff, M. C., Barres, B. A., Burne, J. F., Coles, H. S., Ishizaki, Y. and Jacobson, M. D (1993). Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262, 695-700.[Abstract/Free Full Text]

Rubin, L. L., Gatchalian, C. L., Rimon, G. and Brooks, S. F (1994). The molecular mechanisms of neuronal apoptosis. Curr. Op. Neurobiol 4, 696-702.[Medline]

Slee, E. A., Zhu, H., Chow, S. C., MacFarlane, M., Nicholson, D. W. and Cohen, G.M (1996). Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem. J 315, 21-24.

Thompson, C. L. and Stephenson, F. A (1994). GABAAreceptor subtypesexpressed in cerebellar granule cells: a devlopmental study. J. Neurochem 62, 2037-2044.[Medline]

Tsujimoto, Y., Gorham, J., Cossman, J., Jaffe, E. and Croce, C. M (1985). The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229, 1390-1393.[Abstract/Free Full Text]

Vaux, D. L., Weissman, I. L. and Kim, S. K (1992). Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 258, 1955-1957.[Abstract/Free Full Text]

Veis Novack, D. and Korsmeyer, S. J (1994). Bcl-2 protein expression during murine development. Amer. J. Pathol 145, 61-73.[Abstract]

Veis, D. J., Sorenson, C. M., Shutter, J. R. and Korsmeyer, S. J (1993). Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75, 229-240.[Medline]

White, E (1996). Life, death and the pursuit of apoptosis. Genes Dev 10, 1-15.[Free Full Text]

Wood, K. A., Dipasquale, B. and Youle, R. J (1993). In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum. Neuron 11, 621-632.[Medline]

Wyllie, A. H., Kerr, J. F. R. and Currie, A. R (1980). Cell death: the significance of apoptosis. Int. Rev. Cytol 68, 251-306.[Medline]

Xue, D. and Horvitz, H. R (1995). Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature 377, 248-251.[Medline]

Yang, E., Zha, J., Jockel, J., Boise, L. H., Thompson, C. B. and Korsmeyer, S. J (1995). Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death. Cell 80, 285-291.[Medline]

Yin, X.-M., Oltvai, Z. N. and Korsmeyer, S. J (1994). BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369, 321-323.[Medline]

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				F. Luciano, D. Zhai, X. Zhu, B. Bailly-Maitre, J.-E. Ricci, A. C. Satterthwait, and J. C. Reed Cytoprotective Peptide Humanin Binds and Inhibits Proapoptotic Bcl-2/Bax Family Protein BimEL J. Biol. Chem., April 22, 2005; 280(16): 15825 - 15835. [Abstract] [Full Text] [PDF]

				S. H. Zeisel Nutritional Importance of Choline for Brain Development J. Am. Coll. Nutr., December 1, 2004; 23(suppl_6): 621S - 626S. [Abstract] [Full Text] [PDF]

				S. J. Vannucci and H. Hagberg Hypoxia-ischemia in the immature brain J. Exp. Biol., August 15, 2004; 207(18): 3149 - 3154. [Abstract] [Full Text] [PDF]

				H. Vaghefi, A. L. Hughes, and K. E. Neet Nerve Growth Factor Withdrawal-mediated Apoptosis in Naive and Differentiated PC12 Cells through p53/Caspase-3-dependent and -independent Pathways J. Biol. Chem., April 9, 2004; 279(15): 15604 - 15614. [Abstract] [Full Text] [PDF]

				L. F. Jarskog, E. S. Selinger, J. A. Lieberman, and J. H. Gilmore Apoptotic Proteins in the Temporal Cortex in Schizophrenia: High Bax/Bcl-2 Ratio Without Caspase-3 Activation Am J Psychiatry, January 1, 2004; 161(1): 109 - 115. [Abstract] [Full Text] [PDF]

				C. N. Craciunescu, E. C. Brown, M.-H. Mar, C. D. Albright, M. R. Nadeau, and S. H. Zeisel Folic Acid Deficiency During Late Gestation Decreases Progenitor Cell Proliferation and Increases Apoptosis in Fetal Mouse Brain J. Nutr., January 1, 2004; 134(1): 162 - 166. [Abstract] [Full Text] [PDF]

				J. Gilley, P. J. Coffer, and J. Ham FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons J. Cell Biol., August 18, 2003; 162(4): 613 - 622. [Abstract] [Full Text] [PDF]

				W. Sun, T. W. Gould, S. Vinsant, D. Prevette, and R. W. Oppenheim Neuromuscular Development after the Prevention of Naturally Occurring Neuronal Death by Bax Deletion J. Neurosci., August 13, 2003; 23(19): 7298 - 7310. [Abstract] [Full Text] [PDF]

				S. Gianino, J. R. Grider, J. Cresswell, H. Enomoto, and R. O. Heuckeroth GDNF availability determines enteric neuron number by controlling precursor proliferation Development, May 15, 2003; 130(10): 2187 - 2198. [Abstract] [Full Text] [PDF]

				W. Chen, J. Sulcove, I. Frank, S. Jaffer, H. Ozdener, and D. L. Kolson Development of a Human Neuronal Cell Model for Human Immunodeficiency Virus (HIV)-Infected Macrophage-Induced Neurotoxicity: Apoptosis Induced by HIV Type 1 Primary Isolates and Evidence for Involvement of the Bcl-2/Bcl-xL-Sensitive Intrinsic Apoptosis Pathway J. Virol., August 12, 2002; 76(18): 9407 - 9419. [Abstract] [Full Text] [PDF]

				P. Eversole-Cire, J. Chen, and M. I. Simon Bax Is Not the Heterodimerization Partner Necessary for Sustained Anti-photoreceptor-Cell-Death Activity of Bcl-2 Invest. Ophthalmol. Vis. Sci., May 1, 2002; 43(5): 1636 - 1644. [Abstract] [Full Text] [PDF]

				G. Middleton and A. M. Davies Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo Development, December 1, 2001; 128(23): 4715 - 4728. [Abstract] [Full Text] [PDF]

				Y. Nakao, H. Otani, T. Yamamura, R. Hattori, M. Osako, and H. Imamura Insulin-like growth factor 1 prevents neuronal cell death and paraplegia in the rabbit model of spinal cord ischemia J. Thorac. Cardiovasc. Surg., July 1, 2001; 122(1): 136 - 143. [Abstract] [Full Text] [PDF]

				R. Seidl, B. Bidmon, M. Bajo, B. C. Yoo, N. Cairns, E. C. LaCasse, and G. Lubec Evidence for Apoptosis in the Fetal Down Syndrome Brain J Child Neurol, June 1, 2001; 16(6): 438 - 442. [Abstract] [PDF]

				F. J. Northington, D. M. Ferriero, D. L. Flock, and L. J. Martin Delayed Neurodegeneration in Neonatal Rat Thalamus after Hypoxia-Ischemia Is Apoptosis J. Neurosci., March 15, 2001; 21(6): 1931 - 1938. [Abstract] [Full Text] [PDF]

				D. Chrysis, A. S. Calikoglu, P. Ye, and A. J. D'Ercole Insulin-Like Growth Factor-I Overexpression Attenuates Cerebellar Apoptosis by Altering the Expression of Bcl Family Proteins in a Developmentally Specific Manner J. Neurosci., March 1, 2001; 21(5): 1481 - 1489. [Abstract] [Full Text] [PDF]

				G Middleton, S Wyatt, N Ninkina, and A. Davies Reciprocal developmental changes in the roles of Bcl-w and Bcl-x(L) in regulating sensory neuron survival Development, January 2, 2001; 128(3): 447 - 457. [Abstract] [PDF]

				S. Ghatan, S. Larner, Y. Kinoshita, M. Hetman, L. Patel, Z. Xia, R. J. Youle, and R. S. Morrison p38 MAP Kinase Mediates Bax Translocation in Nitric Oxide-induced Apoptosis in Neurons J. Cell Biol., July 24, 2000; 150(2): 335 - 348. [Abstract] [Full Text] [PDF]

				F. Selimi, M. W. Vogel, and J. Mariani Bax Inactivation in Lurcher Mutants Rescues Cerebellar Granule Cells But Not Purkinje Cells or Inferior Olivary Neurons J. Neurosci., July 15, 2000; 20(14): 5339 - 5345. [Abstract] [Full Text] [PDF]

				O. F. X. ALMEIDA, G. L. CONDÉ, C. CROCHEMORE, B. A. DEMENEIX, D. FISCHER, A. H. S. HASSAN, M. MEYER, F. HOLSBOER, and T. M. MICHAELIDIS Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate FASEB J, April 1, 2000; 14(5): 779 - 790. [Abstract] [Full Text]

				D. Hicks and J. Sahel The Implications of Rod-Dependent Cone Survival for Basic and Clinical Research Invest. Ophthalmol. Vis. Sci., December 1, 1999; 40(13): 3071 - 3074. [Full Text] [PDF]

				S. P. Cregan, J. G. MacLaurin, C. G. Craig, G. S. Robertson, D. W. Nicholson, D. S. Park, and R. S. Slack Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons J. Neurosci., September 15, 1999; 19(18): 7860 - 7869. [Abstract] [Full Text] [PDF]

				M. D. Johnson, Y. Kinoshita, H. Xiang, S. Ghatan, and R. S. Morrison Contribution of p53-Dependent Caspase Activation to Neuronal Cell Death Declines with Neuronal Maturation J. Neurosci., April 15, 1999; 19(8): 2996 - 3006. [Abstract] [Full Text] [PDF]

				I. Martinou, S. Desagher, R. Eskes, B. Antonsson, E. Andre, S. Fakan, and J.-C. Martinou The Release of Cytochrome c from Mitochondria during Apoptosis of NGF-deprived Sympathetic Neurons Is a Reversible Event J. Cell Biol., March 8, 1999; 144(5): 883 - 889. [Abstract] [Full Text] [PDF]

				M. A. Vogelbaum, J. X. Tong, and K. M. Rich Developmental Regulation of Apoptosis in Dorsal Root Ganglion Neurons J. Neurosci., November 1, 1998; 18(21): 8928 - 8935. [Abstract] [Full Text] [PDF]