The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure

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Amano, H (1960). Role of the somitic tissue in the limb development of the urodelan amphibia. Arch. Biol 71, 343-366.

Carrington, J. L. and Fallon, J. F (1984). The stages of flank ectoderm capable of responding to ridge induction in the chick embryo. J. Embryol. Exp. Morph 84, 19-34.[Medline]

Carrington, J. L. and Fallon, J. F (1986). Experimental manipulation leading to induction of dorsal ectoderm ridges on normal limb buds results in a phenocopy of the Eudiplopodia chick mutant. Dev. Biol 116, 130-137.[Medline]

Carrington, J. L. and Fallon, J. F (1988). Initial limb budding is independent of apical ectodermal ridge activity: evidence from a limbless mutant. Development 104, 361-367.[Abstract/Free Full Text]

Catala, M., Teillet, M.-A., De Robertis, E. M. and Le Douarin, N. M (1996). A spinal cord fate map in the avian embryo: while regressing, Hensen's node lays down the notochord and floor plate thus joining the spinal cord lateral walls. Development 122, 2599-2610.[Abstract]

Christ, B., Jacob, H. J. and Jacob, M (1974). Uber den Ursprung der Flugelmuskulatur. Experimentelle Untersuchugen mit Wachtelund Huhnerembryonen. Experientia 30, 1446-1449.[Medline]

Crossley, H. P., Minowanda, G., MacArthur, C. A. and Martin, G. A (1996). Roles for FGF8 in the induction, initiation and maintenance of chick limb development. Cell 84, 127-136.[Medline]

Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L (1991). Examining pattern formation in mouse, chicken and frog embryos with an En -specific antiserum. Development 111, 287-298.[Abstract]

Dealy, C. N., Roth, A., Ferrari, D., Brown, A. M. C. and Kosher, R. A (1993). Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech. Dev 43, 175-186.[Medline]

Dealy, C. N. and Kosher, R. A (1996). IGF-I and insulin in the acquisition of limb-forming ability by the embryonic lateral plate. Dev. Biol 177, 291-299.[Medline]

Detwiler, S. R (1933). On the time of determination of the antero-posterior axis of the forelimb in Amblystoma. J. Exp. Zool 64, 405-414.

Eichmann, A., Marcelle, C., Breant, C. and Le Douarin, N. M (1993). Molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development. Mech. Dev 42, 33-48.[Medline]

Gardner, C. A. and Barald, K. F (1992). Expression patterns of Engrailed -like proteins in the chick embryos. Dev. Dyn 193, 370-388.[Medline]

Geduspan, J. S. and MacCabe, J. A (1987). The ectodermal control of mesodermal patterns of differentiation in the developing chick wing. Dev. Biol 124, 398-408.[Medline]

Geduspan, J. S. and MacCabe, J. A (1989). Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development. Anat. Rec 224, 79-87.[Medline]

Geduspan, J. S. and Solursh, M (1992). A growth-promoting influence from the mesonephros during limb outgrowth. Dev. Biol 151, 242-250.[Medline]

Grieshammer, U., Minowada, G., Pisenti, J. M., Abbott, U. K. and Martin, G. A (1996). The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation. Development 122, 3851-3861.[Abstract]

Hamburger, V. and Hamilton, H. L (1951). A series of normal stages in the development of chick embryos. J. Morphol 88, 49-92.

Harrison, R. G (1918). Experiments on the development of the fore limb ofAmblystoma, a self-differenciating equipotential system. J. Exp. Zool 25, 413-461.

Harrison, R. G (1921). On relations of symmetry in transplanted limbs. J. Exp. Zool 32, 1-136.

Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375, 787-790.[Medline]

Hornbruch, A. and Wolpert, L (1991). The spatial and temporal distribution of polarizing activity in the flank of the pre-limb-bud stages in the chick embryo. Development 111, 725-731.[Abstract]

Kieny, M (1960). R\231le inducteur du mesoderme dans la differenciation precoce du bourgeon de membre chez l'embryon de poulet. J. Embryol. Exp. Morph 8, 457-67.

Kieny, M. and Brugal, M (1977). Morphogenese du membre chez l'embryon de poulet: competence de l'ectoderme embryonnaire et extra-embryonnaire. Arch. Anat. Microsc 66, 235-252.[Medline]

Le Douarin, N (1969). Particularites du noyau interphasique chez la Caille japonaise ( Coturnix coturnix japonica ). Utilisation de ces particularites comme \324marquage biologique' dans les recherches sur les interactions tissulaires et les migrations cellulaires au cours de l'ontogenese. Bull. Biol. Fr. Belg 103, 435-452.[Medline]

Logan, C., Hanks, M. C., Noble-Topham, S., Nallainathan, D., Provart, N. J. and Joyner, A. L (1992). Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions. Dev. Genet 13, 345-358.[Medline]

Loomis, C. A., Harris, E., Michaud, J., Wurst, W., Hanks, M. and Joyner, A. L (1996). The Engrailed-1 gene and ventral limb patterning. Nature 382, 360-363.[Medline]

MacCabe, J. A., Errick, J. and Saunders, J. W. J (1974). Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo. Dev. Biol 39, 69-82.[Medline]

Mahmood, R., Bresnick, J., Hornbruch, A., Mahony, C., Morton, N., Colquhoun, K., Martin, P., Lumsden, A., Dickson, C. and Mason, I (1995). A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr. Biol 5, 797-806.[Medline]

Meinhardt, H (1983). A boundary model for pattern formation in vertebrate limbs. J. Embryol. Exp. Morphol 76, 115-137.[Medline]

Noramly, S., Pisenti, J., Abbott, U. and Morgan, B (1996). Gene expression in the limbless mutant: polarized gene expression in the absence of Shh and an AER. Dev. Biol 179, 339-346.[Medline]

Ordahl, C. P. and Le Douarin, N. M (1992). Two myogenic lineages within the developing somite. Development 114, 339-353.[Abstract]

Parr, B. A. and McMahon, A. P (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.[Medline]

Pautou, M.-P (1977). Etablissement de l'axe dorso-ventral dans le pied de l'embryon de poulet. J. Embryol. Exp. Morph 42, 177-194.

Pinot, M (1970). Le r\231le du mesoderme somitique dans la morphogenese precoce des membres de l'embryon de poulet. J. Embryol. Exp. Morph 23, 109-151.[Medline]

Prahlad, G., Skala, G., Jones, D., and Briles, W (1979). Limbless : a new genetic variant mutant in the chick. J. Exp. Zool 209, 427-434.[Medline]

Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C (1993). Sonic Hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M. and Tabin, C (1995). Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.[Medline]

Ros, M. A., Lopes-Mart\222nez, A., Simandl, B. K., Rodriguez, C., Izpis\234a Belmonte, J. C., Dahn, R. and Fallon, J. F (1996). The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122, 2319-2330.[Abstract]

Ruud, G (1926). The symmetry relations of transplanted limbs in Amblystoma tigrinum. J. Exp. Zool 46, 121-141.

Saunders, J. W. J (1948). The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool 108, 363-403.[Medline]

Saunders, J. W. and Reuss, C (1974). Inductive and axial properties of propective wing-bud mesoderm in the chick embryo. Dev. Biol 38, 41-50.[Medline]

Stephens, T. D. and McNulty, T. R (1981). Evidence for a metameric pattern in the development of the chick humerus. J. Embryol. Exp. Morphol 61, 191-205.[Medline]

Stephens, T. D., Baker, W. C., Cotterell, J. W., Edwards, D. R., Pugmire, D. S., Roberts, S. G., Shaker, M. R., Willis, H. J. and Winger, K. P (1993). Evaluation of the chick wing territory as an equipotential self-differentiating system. Dev. Dyn 197, 157-168.[Medline]

Summerbell, D., Lewis, J. H. and Wolpert, L (1973). Positional information in chick limb morphogenesis. Nature 224, 492-496.

Swett, F. H (1927). Differentiation of the amphibian limb. J. Exp. Zool 47, 385-440.

Swett, F. H (1938). Experiments upon the relationship of surrounding areas to polarization of the dorsoventral limb-axis in Amblystoma punctatum. J. Exp. Zool 78, 81-100.

Tickle, C. and Eichele, G (1994). Vertebrate limb development. Annu. Rev. Cell Biol 10, 121-152.

Todt, W. L. and Fallon, J. F (1984). Development of the apical ectodermal ridge in the chick wing bud. J. Embryol. Exp. Morph 80, 21-41.[Medline]

Vaahtokari, A., \201berg, T. and Thesleff, I (1996). Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4. Development 122, 121-129.[Abstract]

Vogel, A., Rodriguez, C., Warnken, W. and Izpis\234a Belmonte, J. C (1995). Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720.[Medline]

Vogel, A., Rodriguez, C. and Izpis\234a Belmonte, J. C (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.[Abstract]

Wolff, E (1936). Les bases de la teratogenese experimentale des vertebres amniotes d'apres les resultats de methodes directes. Arch. Anat. Histol. Embryol 22, 1-382.

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Articles by Michaud, J. L.

Articles by Le Douarin, N. M.

				Y. Lallemand, M.-A. Nicola, C. Ramos, A. Bach, C. S. Cloment, and B. Robert Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development Development, July 1, 2005; 132(13): 3003 - 3014. [Abstract] [Full Text] [PDF]

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				I. Fliniaux, J. P. Viallet, and D. Dhouailly Signaling dynamics of feather tract formation from the chick somatopleure Development, August 15, 2004; 131(16): 3955 - 3966. [Abstract] [Full Text] [PDF]

				M. Gorivodsky and P. Lonai Novel roles of Fgfr2 in AER differentiation and positioning of the dorsoventral limb interface Development, November 15, 2003; 130(22): 5471 - 5479. [Abstract] [Full Text] [PDF]

				C. Liu, E. Nakamura, V. Knezevic, S. Hunter, K. Thompson, and S. Mackem A role for the mesenchymal T-box gene Brachyury in AER formation during limb development Development, April 1, 2003; 130(7): 1327 - 1337. [Abstract] [Full Text] [PDF]

				K. Ahn, Y. Mishina, M. C. Hanks, R. R. Behringer, and E. B. Crenshaw III BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb Development, November 15, 2001; 128(22): 4449 - 4461. [Abstract] [Full Text] [PDF]

				R. A. Kimmel, D. H. Turnbull, V. Blanquet, W. Wurst, C. A. Loomis, and A. L. Joyner Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation Genes & Dev., June 1, 2000; 14(11): 1377 - 1389. [Abstract] [Full Text]

				G. R. Martin The roles of FGFs in the early development of vertebrate�limbs Genes & Dev., June 1, 1998; 12(11): 1571 - 1586. [Full Text]

				C Rodriguez-Esteban, J. Schwabe, J. Pena, D. Rincon-Limas, J Magallon, J Botas, and J. Belmonte Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth Development, January 10, 1998; 125(20): 3925 - 3934. [Abstract] [PDF]

				J. Gibson-Brown, S. Agulnik, L. Silver, L Niswander, and V. Papaioannou Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development Development, January 7, 1998; 125(13): 2499 - 2509. [Abstract] [PDF]

				M Ensini, T. Tsuchida, H. Belting, and T. Jessell The control of rostrocaudal pattern in the developing spinal cord: specification of motor neuron subtype identity is initiated by signals from paraxial mesoderm Development, January 3, 1998; 125(6): 969 - 982. [Abstract] [PDF]

				C. Loomis, R. Kimmel, C. Tong, J Michaud, and A. Joyner Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs Development, January 3, 1998; 125(6): 1137 - 1148. [Abstract] [PDF]

				J. Cygan, R. Johnson, and A. McMahon Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants Development, January 12, 1997; 124(24): 5021 - 5032. [Abstract] [PDF]

				M Altabef, J. Clarke, and C Tickle Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb Development, January 11, 1997; 124(22): 4547 - 4556. [Abstract] [PDF]