The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development

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				A. Lux, C. Beil, M. Majety, S. Barron, C. J. Gallione, H.-M. Kuhn, J. N. Berg, P. Kioschis, D. A. Marchuk, and M. Hafner Human Retroviral gag- and gag-pol-like Proteins Interact with the Transforming Growth Factor-{beta} Receptor Activin Receptor-like Kinase 1 J. Biol. Chem., March 4, 2005; 280(9): 8482 - 8493. [Abstract] [Full Text] [PDF]

				M. Takeda, F. Otsuka, K. Nakamura, K. Inagaki, J. Suzuki, D. Miura, H. Fujio, H. Matsubara, H. Date, T. Ohe, et al. Characterization of the Bone Morphogenetic Protein (BMP) System in Human Pulmonary Arterial Smooth Muscle Cells Isolated from a Sporadic Case of Primary Pulmonary Hypertension: Roles of BMP Type IB Receptor (Activin Receptor-Like Kinase-6) in the Mitotic Action Endocrinology, September 1, 2004; 145(9): 4344 - 4354. [Abstract] [Full Text] [PDF]

				Z. Liu, W. Shi, X. Ji, C. Sun, W. S. S. Jee, Y. Wu, Z. Mao, T. R. Nagy, Q. Li, and X. Cao Molecules Mimicking Smad1 Interacting with Hox Stimulate Bone Formation J. Biol. Chem., March 19, 2004; 279(12): 11313 - 11319. [Abstract] [Full Text] [PDF]

				J. Suzuki, F. Otsuka, K. Inagaki, M. Takeda, T. Ogura, and H. Makino Novel Action of Activin and Bone Morphogenetic Protein in Regulating Aldosterone Production by Human Adrenocortical Cells Endocrinology, February 1, 2004; 145(2): 639 - 649. [Abstract] [Full Text] [PDF]

				A. Moustakas and C.-H. Heldin Ecsit-ement on the crossroads of Toll and BMP signal transduction Genes & Dev., December 1, 2003; 17(23): 2855 - 2859. [Full Text] [PDF]

				C. Xiao, J.-h. Shim, M. Kluppel, S. S.-M. Zhang, C. Dong, R. A. Flavell, X.-Y. Fu, J. L. Wrana, B. L.M. Hogan, and S. Ghosh Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis Genes & Dev., December 1, 2003; 17(23): 2933 - 2949. [Abstract] [Full Text] [PDF]

				H. Benchabane and J. L. Wrana GATA- and Smad1-Dependent Enhancers in the Smad7 Gene Differentially Interpret Bone Morphogenetic Protein Concentrations Mol. Cell. Biol., September 15, 2003; 23(18): 6646 - 6661. [Abstract] [Full Text] [PDF]

				K. Jiao, Y. Zhou, and B. L. M. Hogan Identification of mZnf8, a Mouse Kruppel-Like Transcriptional Repressor, as a Novel Nuclear Interaction Partner of Smad1 Mol. Cell. Biol., November 1, 2002; 22(21): 7633 - 7644. [Abstract] [Full Text] [PDF]

				Y. Qian, S. Shirasawa, C.-L. Chen, L. Cheng, and Q. Ma Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1 Genes & Dev., May 15, 2002; 16(10): 1220 - 1233. [Abstract] [Full Text] [PDF]

				T. Lopez-Rovira, E. Chalaux, J. Massague, J. L. Rosa, and F. Ventura Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation of Id1 Gene J. Biol. Chem., January 25, 2002; 277(5): 3176 - 3185. [Abstract] [Full Text] [PDF]

				G. T. Park and M. I. Morasso Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Res., January 15, 2002; 30(2): 515 - 522. [Abstract] [Full Text] [PDF]

				A. Hanyu, Y. Ishidou, T. Ebisawa, T. Shimanuki, T. Imamura, and K. Miyazono The N domain of Smad7 is essential for specific inhibition of transforming growth factor-{beta} signaling J. Cell Biol., December 10, 2001; 155(6): 1017 - 1028. [Abstract] [Full Text] [PDF]

				Y. Qian, B. Fritzsch, S. Shirasawa, C.-L. Chen, Y. Choi, and Q. Ma Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3 Genes & Dev., October 1, 2001; 15(19): 2533 - 2545. [Abstract] [Full Text] [PDF]

				J. A. Visser, R. Olaso, M. Verhoef-Post, P. Kramer, A. P. N. Themmen, and H. A. Ingraham The Serine/Threonine Transmembrane Receptor ALK2 Mediates Mullerian Inhibiting Substance Signaling Mol. Endocrinol., June 1, 2001; 15(6): 936 - 945. [Abstract] [Full Text] [PDF]

				T. R. Clarke, Y. Hoshiya, S. E. Yi, X. Liu, K. M. Lyons, and P. K. Donahoe Mullerian Inhibiting Substance Signaling Uses a Bone Morphogenetic Protein (BMP)-Like Pathway Mediated by ALK2 and Induces Smad6 Expression Mol. Endocrinol., June 1, 2001; 15(6): 946 - 959. [Abstract] [Full Text] [PDF]

				W. Wang, F. V. Mariani, R. M. Harland, and K. Luo Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells PNAS, December 19, 2000; 97(26): 14394 - 14399. [Abstract] [Full Text] [PDF]

				D. G. Monroe, D. F. Jin, and M. M. Sanders Estrogen Opposes the Apoptotic Effects of Bone Morphogenetic Protein 7 on Tissue Remodeling Mol. Cell. Biol., July 1, 2000; 20(13): 4626 - 4634. [Abstract] [Full Text]

				K. Kusanagi, H. Inoue, Y. Ishidou, H. K. Mishima, M. Kawabata, and K. Miyazono Characterization of a Bone Morphogenetic Protein-responsive Smad-binding Element Mol. Biol. Cell, February 1, 2000; 11(2): 555 - 565. [Abstract] [Full Text]

				I. Gupta, M Macias-Silva, S Kim, X Zhou, T. Piscione, C Whiteside, J. Wrana, and N. Rosenblum BMP-2/ALK3 and HGF signal in parallel to regulate renal collecting duct morphogenesis J. Cell Sci., January 1, 2000; 113(2): 269 - 278. [Abstract] [PDF]

				S. Akiyoshi, H. Inoue, J.-i. Hanai, K. Kusanagi, N. Nemoto, K. Miyazono, and M. Kawabata c-Ski Acts as a Transcriptional Co-repressor in Transforming Growth Factor-beta Signaling through Interaction with Smads J. Biol. Chem., December 3, 1999; 274(49): 35269 - 35277. [Abstract] [Full Text] [PDF]

				R. Meech, P. Kallunki, G. M. Edelman, and F. S. Jones A binding site for homeodomain and Pax proteins is necessary for L1 cell adhesion molecule gene expression by Pax-6 and bone morphogenetic proteins PNAS, March 2, 1999; 96(5): 2420 - 2425. [Abstract] [Full Text] [PDF]

				T. Brummel, S. Abdollah, T. E. Haerry, M. J. Shimell, J. Merriam, L. Raftery, J. L. Wrana, and M. B. O'Connor The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development Genes & Dev., January 1, 1999; 13(1): 98 - 111. [Abstract] [Full Text]

				M. Macias-Silva, P. A. Hoodless, S. J. Tang, M. Buchwald, and J. L. Wrana Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2 J. Biol. Chem., October 2, 1998; 273(40): 25628 - 25636. [Abstract] [Full Text] [PDF]

				A. Kumar, V. Novoselov, A. J. Celeste, N. M. Wolfman, P. ten Dijke, and M. R. Kuehn Nodal Signaling Uses Activin and Transforming Growth Factor-beta Receptor-regulated Smads J. Biol. Chem., January 5, 2001; 276(1): 656 - 661. [Abstract] [Full Text] [PDF]

				K. Kusanagi, M. Kawabata, H. K. Mishima, and K. Miyazono alpha -Helix 2 in the Amino-terminal Mad Homology 1 Domain Is Responsible for Specific DNA Binding of Smad3 J. Biol. Chem., July 20, 2001; 276(30): 28155 - 28163. [Abstract] [Full Text] [PDF]