Genetic interactions and dosage effects of Polycomb group genes in mice

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Bel, S.
	Articles by Van Lohuizen, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Bel, S.
	Articles by Van Lohuizen, M.

Akasaka, T., Kanno, M., Balling, R., Mieza, M.A., Taniguchi, M. and Koseki, H (1996). A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. Development 122, 1513-1522.[Abstract]

Alkema, M.J., Bronk, M., Verhoeven, E., Otte, A., van't Veer, L.J., Berns, A. and van Lohuizen, M (1997). Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes. Dev 11, 226-240.[Abstract/Free Full Text]

Alkema, M.J., Jacobs, J., Voncken, J.W., Jenkins, N.A., Copeland, N.G., Satijn, D.P.E., Otte, A.P., Berns, A. and van Lohuizen, M (1997). MPc2, a New Murine Homolog of the Drosophila Polycomb Protein is a Member of the Mouse Polycomb Transcriptional Repressor Complex. J. Mol. Biol 273, 993-1003.[Medline]

Alkema, M.J., van der Lugt, N.M., Bobeldijk, R.C., Berns, A. and van Lohuizen, M (1995). Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice. Nature 374, 724-727.[Medline]

Busturia, A. and Bienz, M (1993). Silencers in abdominal-B, a homeotic Drosophila gene. EMBO J 12, 1415-1425.[Medline]

Carrington, E.A. and Jones, R.S (1996). The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122, 4073-4083.[Abstract]

Casares, F. and Sanchez-Herrero, E (1995). Regulation of the infraabdominal regions of the bithorax complex of Drosophila by gap genes. Development 121, 1855-1866.[Abstract]

Castelli-Gair, J., Muller, J. and Bienz, M (1992). Function of an Ultrabithorax minigene in imaginal cells. Development 114, 877-886.[Abstract]

Core, N., Bel, S., Gaunt, S.J., Aurrand-Lions, M., Pearce, J., Fisher, A. and Djabali, M (1997). Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. Development 124, 721-729.[Abstract]

DeCamillis, M., Cheng, N.S., Pierre, D. and Brock, H.W (1992). The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes. Dev 6, 223-232.[Abstract/Free Full Text]

Dura, J.M., Brock, H.W. and Santamaria, P (1985). Polyhomeotic: a gene of Drosophila melanogaster required for correct expression of segmental identity. Mol. Gen. Genet 198, 213-220.[Medline]

Erselius, J.R., Goulding, M.D. and Gruss, P (1990). Structure and expression pattern of the murine Hox-3.2 gene. Development 110, 629-642.[Abstract/Free Full Text]

Franke, A., DeCamillis, M., Zink, D., Cheng, N., Brock, H.W. and Paro, R (1992). Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster. EMBO J 11, 2-.

Gould, A (1997). Functions of mammalian Polycomb group and trithorax group related genes. Cur. Op. Gen. Dev 7, 488-494.[Medline]

Gunster, M.J., Satijn, D.P., Hamer, K.M., den Blaauwen, J.L., de Bruijn, D., Alkema, M.J., van Lohuizen, M., van Driel, R. and Otte, A.P (1997). Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic. Mol. Cell Biol 17, 2326-2335.[Abstract]

Harding, K. and Levine, M (1988). Gap genes define the limits of antennapedia and bithorax gene expression during early development in Drosophila. EMBO J 7, 205-214.[Medline]

Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D (1995). Expression of a Delta homologue in prospective neurons in the chick [see comments]. Nature 375, 787-790.[Medline]

Hobert, O., Sures, I., Ciossek, T., Fuchs, M. and Ullrich, A (1996). Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene. Mech. Dev 55, 171-184.[Medline]

Irish, V.F., Martinez-Arias, A. and Akam, M (1989). Spatial regulation of the Antennapedia and Ultrabithorax homeotic genes during Drosophila early development. EMBO J 8, 1527-1537.[Medline]

James, T.C. and Elgin, S.C (1986). Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol. Cell Biol 6, 3862-3872.[Abstract/Free Full Text]

Jurgens, G (1985). A group of genes controling the spacial expression of the bithorax complex in Drosophila. Nature 316, 153-155.

Kennison, J.A (1993). Transcriptional activation of drosophila homeotic genes from distant regulatory elements. Trends genet 9, 75-79.[Medline]

Lonie, A., D'Andrea, R., Paro, R. and Saint, R (1994). Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development 120, 2629-2636.[Abstract/Free Full Text]

Martin, E.C. and Adler, P.N (1993). The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein. Development 117, 641-655.[Abstract]

McGinnis, W. and Krumlauf, R (1992). Homeobox genes and axial patterning. Cell 68, 283-302.[Medline]

Muller, J. and Bienz, M (1991). Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo. EMBO J 10, 3147-3155.[Medline]

Nomura, M., Takihara, Y. and Shimada, K (1994). Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: one of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila polyhomeotic protein. Differentiation 57, 39-50.[Medline]

Nusslein-Volhard, C. and Wieschaus, E (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.[Medline]

Paro, R (1993). Mechanisms of heritable gene repression during development of Drosophila. Cur. Op. Cell. Biol 5, 999-1005.[Medline]

Paro, R. and Hogness, D.S (1991). The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl. Acad. Sci. U. S. A 88, 263-267.[Abstract/Free Full Text]

Pearce, J.J., Singh, P.B. and Gaunt, S.J (1992). The mouse has a Polycomb-like chromobox gene. Development 114, 921-929.[Abstract]

Pirrotta, V (1997). Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression. Trends genet 13, 314-318.[Medline]

Rastelli, L., Chan, C.S. and Pirrotta, V (1993). Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. EMBO J 12, 1513-1522.[Medline]

Satijn, D.P., Gunster, M.J., van der Vlag, J., Hamer, K.M., Schul, W., Alkema, M.J., Saurin, A.J., Freemont, P.S., van Driel, R. and Otte, A.P (1997). RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor. Mol. Cell Biol 17, 4105-4113.[Abstract]

Simon, J., Chiang, A. and Bender, W (1992). Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development 114, 493-505.[Abstract]

Simon, J., Chiang, A., Bender, W., Shimell, M.J. and O'Connor, M (1993). Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Dev. Biol 158, 131-144.[Medline]

Smouse, D., Goodman, C., Mahowald, A. and Perrimon, N (1988). polyhomeotic: a gene required for the embryonic development of axon pathways in the central nervous system of Drosophila. Genes. Dev 2, 830-842.[Abstract/Free Full Text]

Strutt, H. and Paro, R (1997). The polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes. M. C. B 17, 6773-6783.

Tagawa, M., Sakamoto, T., Shigemoto, K., Matsubara, H., Tamura, Y., Ito, T., Nakamura, I., Okitsu, A., Imai, K. and Taniguchi, M (1990). Expression of novel DNA-binding protein with zinc finger structure in various tumor cells. J. Biol Chem 265, 20021-20026.[Abstract/Free Full Text]

Takihara, Y., Tomotsune, D., Shirai, M., Katoh-Fukui, Y., Nishii, K., Motaleb, M.A., Nomura, M., Tsuchiya, R., Fujita, Y., Shibata, Y.,Higashinakagawa, T. and Shimada, K (1997). Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects [In Process Citation]. Development 124, 3673-3682.[Abstract]

van der Lugt, N.M., Alkema, M., Berns, A. and Deschamps, J (1996). The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression. Mech. Dev 58, 153-164.[Medline]

van der Lugt, N.M., Domen, J., Linders, K., van Roon, M., Robanus-Maandag, E., te Riele, H., van der Valk, M., Deschamps, J., Sofroniew, M. and van Lohuizen, M (1994). Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes. Dev 8, 757-769.[Abstract/Free Full Text]

van Lohuizen, M., Tijms, M., Voncken, J. W., Schumacher, A., Magnuson, T. and Wientjens, E (1998). Interaction of mouse Polycomb-group (Pc-G)proteins Enx-1 and Enx-2 with Eed: Indication for separate Pc-G complexes. Mol. Cell. Biol 18, 3572-3579.[Abstract/Free Full Text]

van Lohuizen, M., Frasch, M., Wientjens, E. and Berns, A (1991). Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2. Nature 353, 353-355.[Medline]

van Lohuizen, M., Verbeek, S., Scheijen, B., Wientjens, E., van der Gulden, H. and Berns, A (1991). Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging [see comments]. Cell 65, 737-752.[Medline]

Wedeen, C., Harding, K. and Levine, M (1986). Spatial regulation of Antennapedia and bithorax gene expression by the Polycomb locus in Drosophila. Cell 44, 739-748.[Medline]

Zink, B. and Paro, R (1989). In vivo binding pattern of a trans-regulator of homeotic genes in Drosophila melanogaster. Nature 337, 468-471.[Medline]

This article has been cited by other articles:

Y. Takada, K.-i. Isono, J. Shinga, J. M. A. Turner, H. Kitamura, O. Ohara, G. Watanabe, P. B. Singh, T. Kamijo, T. Jenuwein, et al.
Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes
Development, February 1, 2007; 134(3): 579 - 590.
[Abstract] [Full Text] [PDF]

S. Y. Kim, S. W. Paylor, T. Magnuson, and A. Schumacher
Juxtaposed Polycomb complexes co-regulate vertebral identity
Development, December 15, 2006; 133(24): 4957 - 4968.
[Abstract] [Full Text] [PDF]

K.-i. Isono, Y.-i. Fujimura, J. Shinga, M. Yamaki, J. O-Wang, Y. Takihara, Y. Murahashi, Y. Takada, Y. Mizutani-Koseki, and H. Koseki
Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes
Mol. Cell. Biol., August 1, 2005; 25(15): 6694 - 6706.
[Abstract] [Full Text] [PDF]

K. Isono, Y. Mizutani-Koseki, T. Komori, M. S. Schmidt-Zachmann, and H. Koseki
Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
Genes & Dev., March 1, 2005; 19(5): 536 - 541.
[Abstract] [Full Text] [PDF]

L. Srinivasan and M. L. Atchison
YY1 DNA binding and PcG recruitment requires CtBP
Genes & Dev., November 1, 2004; 18(21): 2596 - 2601.
[Abstract] [Full Text] [PDF]

S. Bel-Vialar, N. Itasaki, and R. Krumlauf
Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups
Development, March 13, 2003; 129(22): 5103 - 5115.
[Abstract] [Full Text] [PDF]

M. Suzuki, Y. Mizutani-Koseki, Y.-i. Fujimura, H. Miyagishima, T. Kaneko, Y. Takada, T. Akasaka, H. Tanzawa, Y. Takihara, M. Nakano, et al.
Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice
Development, March 11, 2003; 129(18): 4171 - 4183.
[Abstract] [Full Text] [PDF]

J. W. Voncken, B. A. J. Roelen, M. Roefs, S. de Vries, E. Verhoeven, S. Marino, J. Deschamps, and M. van Lohuizen
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
PNAS, March 4, 2003; 100(5): 2468 - 2473.
[Abstract] [Full Text] [PDF]

D. R. Stauffer, T. L. Howard, T. Nyun, and S. M. Hollenberg
CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression
J. Cell Sci., January 7, 2001; 114(13): 2383 - 2393.
[Abstract] [Full Text] [PDF]

T Akasaka, M van Lohuizen, N van der Lugt, Y Mizutani-Koseki, M Kanno, M Taniguchi, M Vidal, M Alkema, A Berns, and H Koseki
Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression
Development, January 5, 2001; 128(9): 1587 - 1597.
[Abstract] [PDF]

M del Mar Lorente, C Marcos-Gutierrez, C Perez, J Schoorlemmer, A Ramirez, T Magin, and M Vidal
Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice
Development, January 12, 2000; 127(23): 5093 - 5100.
[Abstract] [PDF]

J. Lessard, A. Schumacher, U. Thorsteinsdottir, M. van Lohuizen, T. Magnuson, and G. Sauvageau
Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation
Genes & Dev., October 15, 1999; 13(20): 2691 - 2703.
[Abstract] [Full Text]

A. Swain and R. Lovell-Badge
Mammalian sex determination: a molecular drama
Genes & Dev., April 1, 1999; 13(7): 755 - 767.
[Full Text]

J. Zoltewicz, N. Plummer, M. Lin, and A. Peterson
oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1
Development, January 11, 1999; 126(22): 5085 - 5095.
[Abstract] [PDF]

J. I. Bardos, A. J. Saurin, C. Tissot, E. Duprez, and P. S. Freemont
HPC3 Is a New Human Polycomb Orthologue That Interacts and Associates with RING1 and Bmi1 and Has Transcriptional Repression Properties
J. Biol. Chem., September 8, 2000; 275(37): 28785 - 28792.
[Abstract] [Full Text] [PDF]

J. M. Trimarchi, B. Fairchild, J. Wen, and J. A. Lees
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
PNAS, February 13, 2001; 98(4): 1519 - 1524.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Bel, S.

Articles by Van Lohuizen, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Bel, S.

Articles by Van Lohuizen, M.

				S. Y. Kim, S. W. Paylor, T. Magnuson, and A. Schumacher Juxtaposed Polycomb complexes co-regulate vertebral identity Development, December 15, 2006; 133(24): 4957 - 4968. [Abstract] [Full Text] [PDF]

				K.-i. Isono, Y.-i. Fujimura, J. Shinga, M. Yamaki, J. O-Wang, Y. Takihara, Y. Murahashi, Y. Takada, Y. Mizutani-Koseki, and H. Koseki Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes Mol. Cell. Biol., August 1, 2005; 25(15): 6694 - 6706. [Abstract] [Full Text] [PDF]

				K. Isono, Y. Mizutani-Koseki, T. Komori, M. S. Schmidt-Zachmann, and H. Koseki Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1 Genes & Dev., March 1, 2005; 19(5): 536 - 541. [Abstract] [Full Text] [PDF]

				L. Srinivasan and M. L. Atchison YY1 DNA binding and PcG recruitment requires CtBP Genes & Dev., November 1, 2004; 18(21): 2596 - 2601. [Abstract] [Full Text] [PDF]

				S. Bel-Vialar, N. Itasaki, and R. Krumlauf Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups Development, March 13, 2003; 129(22): 5103 - 5115. [Abstract] [Full Text] [PDF]

				M. Suzuki, Y. Mizutani-Koseki, Y.-i. Fujimura, H. Miyagishima, T. Kaneko, Y. Takada, T. Akasaka, H. Tanzawa, Y. Takihara, M. Nakano, et al. Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice Development, March 11, 2003; 129(18): 4171 - 4183. [Abstract] [Full Text] [PDF]

				J. W. Voncken, B. A. J. Roelen, M. Roefs, S. de Vries, E. Verhoeven, S. Marino, J. Deschamps, and M. van Lohuizen Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition PNAS, March 4, 2003; 100(5): 2468 - 2473. [Abstract] [Full Text] [PDF]

				D. R. Stauffer, T. L. Howard, T. Nyun, and S. M. Hollenberg CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression J. Cell Sci., January 7, 2001; 114(13): 2383 - 2393. [Abstract] [Full Text] [PDF]

				T Akasaka, M van Lohuizen, N van der Lugt, Y Mizutani-Koseki, M Kanno, M Taniguchi, M Vidal, M Alkema, A Berns, and H Koseki Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression Development, January 5, 2001; 128(9): 1587 - 1597. [Abstract] [PDF]

				M del Mar Lorente, C Marcos-Gutierrez, C Perez, J Schoorlemmer, A Ramirez, T Magin, and M Vidal Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice Development, January 12, 2000; 127(23): 5093 - 5100. [Abstract] [PDF]

				J. Lessard, A. Schumacher, U. Thorsteinsdottir, M. van Lohuizen, T. Magnuson, and G. Sauvageau Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation Genes & Dev., October 15, 1999; 13(20): 2691 - 2703. [Abstract] [Full Text]

				A. Swain and R. Lovell-Badge Mammalian sex determination: a molecular drama Genes & Dev., April 1, 1999; 13(7): 755 - 767. [Full Text]

				J. Zoltewicz, N. Plummer, M. Lin, and A. Peterson oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1 Development, January 11, 1999; 126(22): 5085 - 5095. [Abstract] [PDF]

				J. I. Bardos, A. J. Saurin, C. Tissot, E. Duprez, and P. S. Freemont HPC3 Is a New Human Polycomb Orthologue That Interacts and Associates with RING1 and Bmi1 and Has Transcriptional Repression Properties J. Biol. Chem., September 8, 2000; 275(37): 28785 - 28792. [Abstract] [Full Text] [PDF]

				J. M. Trimarchi, B. Fairchild, J. Wen, and J. A. Lees The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex PNAS, February 13, 2001; 98(4): 1519 - 1524. [Abstract] [Full Text] [PDF]