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Alberts, A. W., Chen, J., Kuron, G., Hunt, V., Huff, J., Hoffman, C., Rothrock, J., Lopez, M., Joshua, H., Harris, E., et al (1980). Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc. Natl. Acad. Sci. USA 77, 3957-3961.[Abstract/Free Full Text]

Barth, K. A. and Wilson, S. W (1995). Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development 121, 1755-1768.[Abstract]

Belknap, W. M. and Dietschy, J. M (1988). Sterol synthesis and low density lipoprotein clearance in vivo in the pregnant rat, placenta, and fetus. J. Clin. Invest 82, 2077-2085.

Bellairs, R (1958). The conversion of yolk into cytoplasm in the chick blastoderm as shown by electron microscopy. J. Embryol. Exp. Morph 6, 149-161.

Binns, W., Thacker, E. J., James, L. F. and Huffman, W. T (1959). A congenital cyclopian-type malformation in lambs. J. Amer. Vet. Med. Assoc 134, 180-183.

Binns, W., James, L. F., Shupe, J. L. and Everett, G (1963). A congenital cyclopian-type malformation in lambs induced by maternal ingestion of a range plant, Veratrum californicum. Am. J. Vet. Res 24, 1164-1175.[Medline]

Brown, M. S. and Goldstein, J. L (1997). The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340.[Medline]

Carstea, E. D., Morris, J. A., Coleman, K. G., Loftus, S. K., Zhang, D., Cummings, C., Gu, J., Rosenfeld, M. A., Pavan, W. J., Krizman, D. B., et al (1997). Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277, 228-231.[Abstract/Free Full Text]

Chiang, C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H. and Beachy, P. A (1996). Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.[Medline]

Conner, W. E., Johnston, R. and Lin, D. S (1969). Metabolism of cholesterol in the tissues and blood of the chick embryo. J. Lipid Res 10, 388-394.[Abstract]

Corsini, A., Maggi, F. M. and Catapano, A. L (1995). Pharmacology of competitive inhibitors of HMG-CoA reductase. Pharmacol. Res 31, 9-27.[Medline]

Ericson, J., Thor, S., Edlund, T., Jessell, T. M. and Yamada, T (1992). Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science 256, 1555-1560.[Abstract/Free Full Text]

Ericson, J., Morton, S., Kawakami, A., Roelink, H. and Jessell, T. M (1996). Two critical periods of long-range Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell 87, 661-673.[Medline]

Ericson, J., Rashbass, P., Schedl, A., Brenner Morton, S., Kawakami, A., van Heyningen, V., Jessell, T. M. and Briscoe, J (1997). Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90, 169-180.[Medline]

Fan, C. M. and Tessier-Lavigne, M (1994). Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog. Cell 79, 1175-1186.[Medline]

Fan, C. M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. A. and Tessier-Lavigne, M (1995). Long-range sclerotome induction by Sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81, 457-465.[Medline]

Gaffield, W., Benson, M., Lundin, R. E. and Keeler, R. F (1986). Carbon-13 and proton nuclear magnetic resonance spectra of Veratrum alkaloids. J. Nat. Products 49, 286-292.

Gaffield, W. and Keeler, R. F (1996). Steroidal alkaloid teratogens: molecular probes for investigation of craniofacial malformations. J. Toxicol.: Toxin Rev 15, 303-326.

Gil, G., Faust, J. R., Chin, D. J., Goldstein, J. L. and Brown, M. S (1985). Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme. Cell 41, 249-258.[Medline]

Goldstein, J. L. and Brown, M. S (1990). Regulation of the mevalonate pathway. Nature 343, 425-430.[Medline]

Hamburger, V. and Hamilton, H. L (1951). A series of normal stages in the development of the chick embryo. J. Morph 88, 49-92.

Havel, R. J., Eder, H. A. and Bragdon, J. H (1955). The distribution and chemical composition of ultracentifugally separated lipoproteins in human serum. J. Clin. Invest 34, 1345-1353.

Heisenberg, C. P. and Nusslein-Volhard, C (1997). The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev. Biol 184, 85-94.[Medline]

Hua, X., Nohturfft, A., Goldstein, J. L. and Brown, M. S (1996). Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein. Cell 87, 415-426.[Medline]

Kawakami, A., Kimura-Kawakami, M., Nomura, T. and Fujisawa, H (1997). Distributions of PAX6 and PAX7 proteins suggest their involvement in both early and late phases of chick brain development. Mech. Dev 66, 119-130.[Medline]

Keeler, R. F. and Binns, W (1968). Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources. Teratology 1, 5-10.[Medline]

Keeler, R. F (1969). Teratogenic compounds of Veratrum californicum (Durand). VI. The structure of cyclopamine. Phytochemistry 8, 223-225.

Keeler, R. F (1978). Cyclopamine and related steroidal alkaloid teratogens: Their occurrence, structural relationship, and biologic effects. Lipids 13, 708-715.[Medline]

Kelley, R. L., Roessler, E., Hennekam, R. C., Feldman, G. L., Kosaki, K., Jones, M. C., Palumbos, J. C. and Muenke, M (1996). Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: does abnormal cholesterol metabolism affect the function of Sonic Hedgehog?. Am. J. Med. Genet 66, 478-484.[Medline]

Kumagai, H., Chun, K. T. and Simoni, R. D (1995). Molecular dissection of the role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J. Biol. Chem 270, 19107-19113.[Abstract/Free Full Text]

Liem, K. F., Jr., Tremml, G., Roelink, H. and Jessell, T. M (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979.[Medline]

Lisanti, M. P., Scherer, P. E., Vidugiriene, J., Tang, Z., Hermanowski-Vosatka, A., Tu, Y. H., Cook, R. F. and Sargiacomo, M (1994). Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J. Cell Biol 126, 111-126.[Abstract/Free Full Text]

Llirbat, B., Wolf, C., Chevy, F., Citadelle, D., Bereziat, G. and Roux, C (1997). Normal and inhibited cholesterol synthesis in the cultured rat embryo. J. Lipid Res 38, 22-34.[Abstract]

Loftus, S. K., Morris, J. A., Carstea, E. D., Gu, J. Z., Cummings, C., Brown, A., Ellison, J., Ohno, K., Rosenfeld, M. A., Tagle, D. A., et al (1997). Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science 277, 232-235.[Abstract/Free Full Text]

Macdonald, R., Barth, K. A., Xu, Q., Holder, N., Mikkola, I. and Wilson, S. W (1995). Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 121, 3267-3278.[Abstract]

Marigo, V., Davey, R. A., Zuo, Y., Cunningham, J. M. and Tabin, C. J (1996). Biochemical evidence that patched is the Hedgehog receptor. Nature 384, 176-179.[Medline]

Marti, E., Bumcrot, D. A., Takada, R. and McMahon, A. P (1995). Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types. Nature 375, 322-325.[Medline]

Metherall, J. E., Waugh, K. and Li, H (1996). Progesterone inhibits cholesterol biosynthesis in cultured cells. Accumulation of cholesterol precursors. J. Biol. Chem 271, 2627-2633.[Abstract/Free Full Text]

Pera, E. M. and Kessel, M (1997). Patterning of the chick forebrain anlage by the prechordal plate. Development 124, 4153-4162.[Abstract]

Porter, J. A., von Kessler, D. P., Ekker, S. C., Young, K. E., Lee, J. J., Moses, K. and Beachy, P. A (1995). The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374, 363-366.[Medline]

Porter, J. A., Young, K. E. and Beachy, P. A (1996). Cholesterol modification of hedgehog signaling proteins in animal development. Science 274, 255-259.[Abstract/Free Full Text]

Rampini, C., Adriambinintsoa, C., Barbu, V., Maziere, J. C., Maziere, C. and Roux, C (1989). Combined effects of AY9944 and plasma LDL (or whole plasma) on lymphocyte blastic transformation. Biochem. Pharmacol 38, 3887-3891.[Medline]

Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz i Altaba, A., Tanabe, Y., Placzek, M., Edlund, T., Jessell, T. M., and Dodd, J (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.[Medline]

Roelink, H., Porter, J. A., Chiang, C., Tanabe, Y., Chang, D. T., Beachy, P. A. and Jessell, T. M (1995). Floor plate and motor neuron induction bydifferent concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 81, 445-455.[Medline]

Roessler, E., Belloni, E., Gaudenz, K., Jay, P., Berta, P., Scherer, S. W., Tsui, L. C. and Muenke, M (1996). Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat. Genet 14, 357-360.[Medline]

Roux, C. and Aubry, M (1966). Action teratogene chez le rat d'un inhibiteur de la synthese du cholesterol, le AY 9944. C. R. Seances Soc. Biol. Fil 160, 1353-1357.[Medline]

Ruiz i Altaba, A., Placzek, M., Baldassare, M., Dodd, J. and Jessell, T. M (1995). Early stages of notochord and floor plate development in the chick embryo defined by normal and induced expression of HNF-3 beta. Dev. Biol 170, 299-313.[Medline]

Stefanova, I., Horejsi, V., Ansotegui, I. J., Knapp, W. and Stockinger, H (1991). GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science 254, 1016-1019.[Abstract/Free Full Text]

Stone, D. M., Hynes, M., Armanini, M., Swanson, T. A., Gu, Q., Johnson, R. L., Scott, M. P., Pennica, D., Goddard, A., Phillips, H., Noll, M., Hooper, J. E., de Sauvage, F. and Rosenthal, A (1996). The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384, 129-134.[Medline]

Tabata, T. and Kornberg, T. B (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.[Medline]

Tanabe, Y., Roelink, H. and Jessell, T. M (1995). Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation. Curr. Biol 5, 651-658.[Medline]

Tanabe, Y. and Jessell, T. M (1996). Diversity and pattern in the developing spinal cord. Science 274, 1115-1123.[Abstract/Free Full Text]

Tint, G. S., Irons, M., Elias, E. R., Batta, A. K., Frieden, R., Chen, T. S. and Salen, G (1994). Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. N. Engl. J. Med 330, 107-113.[Abstract/Free Full Text]

Tsuchida, T., Ensini, M., Morton, S. B., Baldassare, M., Edlund, T., Jessell, T. M. and Pfaff, S. L (1994). Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957-970.[Medline]

van den Heuvel, M. and Ingham, P. W (1996). Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382, 547-551.[Medline]

Willnow, T. E., Hilpert, J., Armstrong, S. A., Rohlmann, A., Hammer, R. E., Burns, D. E. and Herz, J (1996). Defective forebrain development in mice lacking gp330/megalin. Proc. Natl. Acad. Sci. USA 93, 8460-8464.[Abstract/Free Full Text]

Wolf, C., Chevy, F., Pham, J., Kolf Clauw, M., Citadelle, D., Mulliez, N. and Roux, C (1996). Changes in serum sterols of rats treated with 7-dehydrocholesterol-delta 7-reductase inhibitors: comparison to levels in humans with Smith-Lemli-Opitz syndrome. J. Lipid Res 37, 1325-1333.[Abstract]

Yamada, T., Pfaff, S. L., Edlund, T. and Jessell, T. M (1993). Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 73, 673-686.[Medline]


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 DevelopmentHome page
R. O. Karlstrom, O. V. Tyurina, A. Kawakami, N. Nishioka, W. S. Talbot, H. Sasaki, and A. F. Schier
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development
Development, April 15, 2003; 130(8): 1549 - 1564.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
M. Perron, S. Boy, M. A. Amato, A. Viczian, K. Koebernick, T. Pieler, and W. A. Harris
A novel function for Hedgehog signalling in retinal pigment epithelium differentiation
Development, April 15, 2003; 130(8): 1565 - 1577.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
D. Kang, F. Huang, D. Li, M. Shankland, W. Gaffield, and D. A. Weisblat
A hedgehog homolog regulates gut formation in leech (Helobdella)
Development, April 15, 2003; 130(8): 1645 - 1657.
[Abstract] [Full Text] [PDF]

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 Hum Mol GenetHome page
E. Roessler and M. Muenke
How a Hedgehog might see holoprosencephaly
Hum. Mol. Genet., April 2, 2003; 12(90001): R15 - 25.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
A. M. Kenney, M. D. Cole, and D. H. Rowitch
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
Development, January 1, 2003; 130(1): 15 - 28.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
N. P. Pringle, W.-P. Yu, M. Howell, J. S. Colvin, D. M. Ornitz, and W. D. Richardson
Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains
Development, January 1, 2003; 130(1): 93 - 102.
[Abstract] [Full Text] [PDF]

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 Genes Dev.Home page
J. K. Chen, J. Taipale, M. K. Cooper, and P. A. Beachy
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
Genes & Dev., November 1, 2002; 16(21): 2743 - 2748.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
J. K. Chen, J. Taipale, K. E. Young, T. Maiti, and P. A. Beachy
Small molecule modulation of Smoothened activity
PNAS, October 29, 2002; 99(22): 14071 - 14076.
[Abstract] [Full Text] [PDF]

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 J. Lipid Res.Home page
F. Chevy, F. Illien, C. Wolf, and C. Roux
Limb malformations of rat fetuses exposed to a distal inhibitor of cholesterol biosynthesis
J. Lipid Res., August 1, 2002; 43(8): 1192 - 1200.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
E. Quint, A. Smith, F. Avaron, L. Laforest, J. Miles, W. Gaffield, and M.-A. Akimenko
From the Cover: Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine
PNAS, June 25, 2002; 99(13): 8713 - 8718.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
J. Mathieu, A. Barth, F. M. Rosa, S. W. Wilson, and N. Peyrieras
Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development
Development, January 7, 2002; 129(13): 3055 - 3065.
[Abstract] [Full Text] [PDF]

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 DevelopmentHome page
N. Dahmane, P. Sanchez, Y. Gitton, V. Palma, T. Sun, M. Beyna, H. Weiner, and A. Ruiz i Altaba
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
Development, December 15, 2001; 128(24): 5201 - 5212.
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 DevelopmentHome page
E. Minina, H. M. Wenzel, C. Kreschel, S. Karp, W. Gaffield, A. P. McMahon, and A. Vortkamp
BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation
Development, November 15, 2001; 128(22): 4523 - 4534.
[Abstract] [Full Text] [PDF]