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Aitken, A (1995). 14-3-3 proteins on the MAP. Trends Biochem. Sci 20, 95-97.[Medline]

Ambrosio, L., Mahowald, A. P. and Perrimon, N (1989). Requirement of the Drosophilaraf homologue for torso function. Nature 342, 288-291.[Medline]

Avruch, J., Zhang, X. and Kyriakis, J. M (1994). Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem. Sci 19, 279-283.[Medline]

Baek, K.-H., Fabian, J. R., Sprenger, F., Morrison, D. K. and Ambrosio, L (1996). The activity of D-raf in Torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting. Dev. Biol 175, 191-204.[Medline]

Block, C., Janknecht, R., Hermann, C., Nassar, N. and Wittinghofer, A (1996). A quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo. Nat. Struct. Biol 3, 244-251.[Medline]

Brand, A. H. and Perrimon, N (1994). Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes Dev 8, 629-639.[Abstract/Free Full Text]

Casanova, J., Llimargas, M., Greenwood, S. and Struhl, G (1994). An oncogenic form of human raf can specify terminal body pattern in Drosophila. Mech. Dev 48, 59-64.[Medline]

Chang, H. C. and Rubin, G. M (1997). 14-3-3positively regulates Ras-mediated signaling in Drosophila. Genes Dev 11, 1132-1139.[Abstract/Free Full Text]

Chou, T.-B. and Perrimon, N (1992). Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131, 643-653.[Abstract]

Chou, T.-B. and Perrimon, N (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.[Abstract]

Cutler, R. E. J. and Morrison, D. K (1997). Mammalian Raf-1 is activated by mutations that restore Raf signaling in Drosophila. EMBO J 16, 1953-1960.[Medline]

Daum, G., Eisenmann-Tappe, I., Fries, H., Troppmair, J. and Rapp, U. R (1994). The ins and outs of Raf kinases. Trends Biochem Sci 19, 474-479.[Medline]

Dickson, B., Sprenger, F. and Hafen, E (1992). Prepattern in the developing Drosophila eye revealed by an activated Torso-Sevenless chimeric receptor. Genes Dev 6, 2327-2339.[Abstract/Free Full Text]

Dickson, B., Sprenger, F., Morrison, D. K. and Hafen, E (1992). Raf function downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.[Medline]

Drugan, J. K., Khosravi-Far, R., White, M. A., J., D. C., Sung, Y., Hwang, Y. and Campell, S (1996). Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation. J. Biol. Chem 271, 233-237.[Abstract/Free Full Text]

Duffy, J. B. and Perrimon, N (1994). The Torso pathway in Drosophila: lessons on receptor protein tyrosine kinase signaling and pattern formation. Dev. Biol 166, 380-395.[Medline]

Fabian, J. R., Vojtek, A. B., Cooper, J. A. and Morrison, D. K (1994). A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function. Proc. Natl. Acad. Sci. USA 91, 5982-5986.[Abstract/Free Full Text]

Farnsworth, C. L. and Feig, L. A (1991). Dominant inhibitory mutations in the Mg+-binding site of RasHprevents its activation by GTP. Mol. Cell. Biol 11, 4822-4829.[Abstract/Free Full Text]

Farrar, M. A., Alberola-Ila, J. and Perlmutter, R. M (1996). Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization. Nature 383, 178-181.[Medline]

Fields, S. and Song, O (1989). A novel genetic system to detect protein-protein interaction. Nature 340, 245-246.[Medline]

Gorman, C., Skinner, R. H., Skelly, J. V., Neidle, S. and Lowe, P. N (1996). Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf. J. Biol. Chem 271, 6713-6719.[Abstract/Free Full Text]

Groshans, J., Bergmann, A., Haffter, P. and Nusslein-Volhard, C (1994). Activation of the kinase Pelle by Tube in the dorsalventral signal transduction pathway of Drosophila embryo. Nature 372, 563-566.[Medline]

Gyuris, J., Golemis, E., Chertkov, H. and Brent, R (1993). Cdi1, a human G1 and S phase phosphatase that associates with Cdk2. Cell 75, 791-803.[Medline]

Hallberg, B., Bayter, S. I. and Downward, J (1994). Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation. J. Biol. Chem 269, 3913-3916.[Abstract/Free Full Text]

Heidecker, G., Huleihel, M., Cleveland, J. L., Kolch, W., Beck, T. W., Lloyd, P., Pawson, T. and Rapp, U. R (1990). Mutational activation of c-raf-1 and definition of the minimal transforming sequence. Mol. Cell. Biol 10, 2503-2512.[Abstract/Free Full Text]

Hou, X. S., Chou, T.-B., Melnick, M. B. and Perrimon, N (1995). The Torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell 81, 63-71.[Medline]

Hu, C., Kariya, K., Tamada, M., Akasaka, K., Shirouzu, M., Yokoyama, S. and Kataoka, T (1995). Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras. J. Biol. Chem 270, 30274-30277.[Abstract/Free Full Text]

Huang, W., Alessandrini, A., Crews, C. M. and Erikson, R. L (1993). Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation. Proc. Natl. Acad. Sci. USA 90, 10947-10951.[Abstract/Free Full Text]

Kockel, L., Vorbruggen, G., J\212ckle, H., Mlodzik, M. and Bohmann, D (1997). Requirement for Drosophila 14-3-3in Raf-dependent photoreceptor development. Gene Dev 11, 1140-1147.[Abstract/Free Full Text]

Kornfeld, K., Hom, D. B. and Horvitz, H. R (1995). The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell 83, 903-913.[Medline]

Leevers, S. J., Paterson, H. F. and Marshall, C. J (1994). Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369, 411-414.[Medline]

Li, W., Skoulakis, E. M. C., Davis, R. L. and Perrimon, N (1997). The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras1-dependent manner. Development 124, 4163-4171.[Abstract]

Lu, X., Melnick, M. B., Hsu, J.-C. and Perrimon, N (1994). Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction. EMBO J 13, 2592-2599.[Medline]

Luo, Z., Tzivion, G., Belshaw, P. J., Vavvas, D., Marshall, M. and Avruch, J (1996). Oligomerization activates c-Raf-1 through a Ras-dependent mechanism. Nature 383, 181-185.[Medline]

Marais, R., Light, Y., Paterson, H. F. and Marshall, C. J (1995). Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J 14, 3136-3145.[Medline]

Marshall, C. J (1994). Map kinase kinase kinase, Map kinase kinase and Map kinase. Curr. Opin. Genet. Dev 4, 82-89.[Medline]

Melnick, M. B., Perkins, L. A., Lee, M., Ambrosio, L. and Perrimon, N (1993). Developmental and molecular characterization of mutations in the Drosophila raf serine-threonine kinase. Development 118, 127-138.[Abstract]

Mineo, C. anderson, R. G. W. and White, M. A (1997). Physical assocation with Ras enhances activation of membrane-bound Raf (RafCAAX). J. Biol. Chem 272, 10345-10348.[Abstract/Free Full Text]

Moodie, S. A., Willumsen, B. M., Weber, M. J. and Wolfman, A (1993). Complexes of Ras-GTP with Raf-1 and mitogen-activated protein kinase kinase. Science 260, 1658-1664.[Abstract/Free Full Text]

Moodie, S. A. and Wolfman, A (1994). The 3Rs of life: Ras, Raf and growth regulation. Trends Genet 10, 44-48.[Medline]

Morrison, D (1994). 14-3-3: modulators or signaling proteins?. Science 266, 56-57.[Free Full Text]

Morrison, D. K. and Cutler, R. E. J (1997). The complexity of Raf-1 regulation. Curr. Opin. Cell Biol 9, 174-179.[Medline]

Mott, H. R., Carpenter, J. W., Zhong, S., Ghosh, S. and Bell, R. M (1996). The solution structure of the Raf-1 cysteine-rich domain: a novel Ras and phospholipid binding site. Proc. Natl. Acad. Sci. USA 93, 8312-8317.[Abstract/Free Full Text]

Nassar, N., Horn, G., Hermann, C., Scherer, A., McCormick, F. and Wittinghofer, A (1995). The 2.2 \201 crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature 375, 554-560.[Medline]

Perrimon, N., Engstrom, L. and Mahowald, A. P (1985). A pupal lethalmutation with apaternally influenced maternal effect on embryonic development in Drosophila melanogaster. Dev. Biol 110, 480-491.[Medline]

Pignoni, F., Baldarelli, R. M., Steingrimsson, E., Diaz, R. J., Patapoutian, A., Merriam, J. R. and Lengyel, J. A (1990). The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily. Cell 62, 151-163.[Medline]

Pignoni, F., Steingrimsson, E. and Lengyel, J. A (1992). bicoid and the terminal system activate tailless expression in the early Drosophila embryo. Development 115, 239-251.[Abstract]

Roy, S., Lane, A., Yan, J., McPherson, R. and Hancock, J. F (1997). Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger. J. Biol. Chem 272, 20139-20145.[Abstract/Free Full Text]

Scheffler, J. E., Waugh, D. S., Bekesi, E., Kiefer, S. E., LoSardo, J. E., Neri, A., Prinzo, K. M., Tsao, K., Wegrzynski, b., Emerson, S. D. and Fry, D. C (1994). Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for interaction with Ras-GTP. J. Biol. Chem 269, 22340-22346.[Abstract/Free Full Text]

Sprenger, F. and Nusslein-Volhard, C (1992). Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 71, 987-1001.[Medline]

Sprenger, F., Trosclair, M. M. and Morrison, D. K (1993). Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction. Molecular and Cellular Biology 13, 1163-1172.[Abstract/Free Full Text]

Stanton, V. P. J., Nichols, D. W., Laudano, A. P. and Cooper, G. M (1989). Definition of the human raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell. Biol 9, 639-647.[Abstract/Free Full Text]

Stokoe, D., MacDonald, G., Cadwallader, K., Symons, M. and Hancock, J. F (1994). Activation of Raf as a result of recruitment to the plasma membrane. Science 264, 1463-1467.[Abstract/Free Full Text]

Sundaram, M. and Han, M (1995). The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83, 889-901.[Medline]

Tautz, D. and Pfeifle, C (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosome 98, 81-85.

Therrien, M., Chang, H. C., Solomon, N. M., Karim, F. D., Wassarman, D. A. and Rubin, G. M (1995). KSR, a novel protein kinase required for RAS signal transduction. Cell 83, 879-888.[Medline]

Therrien, M., Michaud, N. R., Rubin, G. M. and Morrison, D. K (1996). KSR modulates signal propagation within the MAPK cascade. Genes Dev 10, 2684-2695.[Abstract/Free Full Text]

van der Meer, J (1977). Optical clean and permanent whole mount preparation for phase-contrast microscopy of cuticular structures of insect larvae. Dros. Inf. Serv 52, 160-.

Vojtek, A. B., Hollenberg, S. M. and Cooper, J. A (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74, 205-214.[Medline]

Xing, H., Kornfeld, K. and Muslin, A. J (1997). The protein kinase KSR interacts with 14-3-3 protein and Raf. Curr. Biol 7, 294-300.[Medline]

Yu, W., Fantl, W. J., Harrowe, G. and Williams, L. T (1997). Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Curr. Biol 8, 56-64.

Zhang, Y., Yao, B., Delikat, S., Bayoumy, S., Lin, X.-H., Basu, S., McGinley, M., Chan-Hui, P.-Y., Lichenstein, H. and Kolesnick, R (1997). Kinase Suppressor of Ras is ceramide-activated protein kinase. Cell 89, 63-72.[Medline]


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