Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch

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Hindbrain patterning: Krox20 couples segmentation and specification of regional identity
Development, December 15, 2001; 128(24): 4967 - 4978.
[Abstract] [Full Text] [PDF]

M. Manzanares, S. Bel-Vialar, L. Ariza-McNaughton, E. Ferretti, H. Marshall, M. M. Maconochie, F. Blasi, and R. Krumlauf
Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms
Development, September 15, 2001; 128(18): 3595 - 3607.
[Abstract] [Full Text] [PDF]

Y. Zhao and S. S. Potter
Functional specificity of the Hoxa13 homeobox
Development, August 15, 2001; 128(16): 3197 - 3207.
[Abstract] [Full Text] [PDF]

E. D. del Toro, V. Borday, M. Davenne, R. Neun, F. M. Rijli, and J. Champagnat
Generation of a Novel Functional Neuronal Circuit in Hoxa1 Mutant Mice
J. Neurosci., August 1, 2001; 21(15): 5637 - 5642.
[Abstract] [Full Text] [PDF]

A. Gavalas, P. Trainor, L. Ariza-McNaughton, and R. Krumlauf
Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest
Development, August 1, 2001; 128(15): 3017 - 3027.
[Abstract] [Full Text] [PDF]

E van Den Akker, C Fromental-Ramain, W de Graaff, H Le Mouellic, P Brulet, P Chambon, and J Deschamps
Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes
Development, January 5, 2001; 128(10): 1911 - 1921.
[Abstract] [PDF]

R. Cantos, L. K. Cole, D. Acampora, A. Simeone, and D. K. Wu
Patterning of the mammalian cochlea
PNAS, October 24, 2000; 97(22): 11707 - 11713.
[Abstract] [Full Text] [PDF]

S. A. Ross, P. J. McCaffery, U. C. Drager, and L. M. De Luca
Retinoids in Embryonal Development
Physiol Rev, July 1, 2000; 80(3): 1021 - 1054.
[Abstract] [Full Text] [PDF]

G. Grammatopoulos, E Bell, L Toole, A Lumsden, and A. Tucker
Homeotic transformation of branchial arch identity after Hoxa2 overexpression
Development, January 12, 2000; 127(24): 5355 - 5365.
[Abstract] [PDF]

M. Zappone, R Galli, R Catena, N Meani, S De Biasi, E Mattei, C Tiveron, A. Vescovi, R Lovell-Badge, S Ottolenghi, et al.
Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells
Development, January 6, 2000; 127(11): 2367 - 2382.
[Abstract] [PDF]

J. Barrow, H. Stadler, and M. Capecchi
Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse
Development, January 3, 2000; 127(5): 933 - 944.
[Abstract] [PDF]

E Ferretti, H Marshall, H Popperl, M Maconochie, R Krumlauf, and F Blasi
Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins
Development, January 1, 2000; 127(1): 155 - 166.
[Abstract] [PDF]

E. Bell, R. J. Wingate, and A. Lumsden
Homeotic Transformation of Rhombomere Identity After Localized Hoxb1 Misexpression
Science, June 25, 1999; 284(5423): 2168 - 2171.
[Abstract] [Full Text]

J. Barrow and M. Capecchi
Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants
Development, January 11, 1999; 126(22): 5011 - 5026.
[Abstract] [PDF]

M Rossel and M. Capecchi
Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development
Development, January 11, 1999; 126(22): 5027 - 5040.
[Abstract] [PDF]

V Dupe, N. Ghyselinck, O Wendling, P Chambon, and M Mark
Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse
Development, January 11, 1999; 126(22): 5051 - 5059.
[Abstract] [PDF]

S Jungbluth, E Bell, and A Lumsden
Specification of distinct motor neuron identities by the singular activities of individual Hox genes
Development, January 6, 1999; 126(12): 2751 - 2758.
[Abstract] [PDF]

M Maconochie, R Krishnamurthy, S Nonchev, P Meier, M Manzanares, P. Mitchell, and R Krumlauf
Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family
Development, January 4, 1999; 126(7): 1483 - 1494.
[Abstract] [PDF]

K Brunschwig, C Wittmann, R Schnabel, T. Burglin, H Tobler, and F Muller
Anterior organization of the Caenorhabditis elegans embryo by the labial-like Hox gene ceh-13
Development, January 4, 1999; 126(7): 1537 - 1546.
[Abstract] [PDF]

				M. Gouti and A. Gavalas Hoxb1 Controls Cell Fate Specification and Proliferative Capacity of Neural Stem and Progenitor Cells Stem Cells, August 1, 2008; 26(8): 1985 - 1997. [Abstract] [Full Text] [PDF]

				X. Lampe, O. A. Samad, A. Guiguen, C. Matis, S. Remacle, J. J. Picard, F. M. Rijli, and R. Rezsohazy An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4 Nucleic Acids Res., June 1, 2008; 36(10): 3214 - 3225. [Abstract] [Full Text] [PDF]

				T. M. Bosley, M. A. Salih, I. A. Alorainy, D. T. Oystreck, M. Nester, K. K. Abu-Amero, M. A. Tischfield, and E. C. Engle Clinical characterization of the HOXA1 syndrome BSAS variant Neurology, September 18, 2007; 69(12): 1245 - 1253. [Abstract] [Full Text] [PDF]

				T. Shimizu, Y.-K. Bae, and M. Hibi Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue Development, December 1, 2006; 133(23): 4709 - 4719. [Abstract] [Full Text] [PDF]

				D. Chomette, M. Frain, S. Cereghini, P. Charnay, and J. Ghislain Krox20 hindbrain cis-regulatory landscape: interplay between multiple long-range initiation and autoregulatory elements Development, April 1, 2006; 133(7): 1253 - 1262. [Abstract] [Full Text] [PDF]

				C. L. McNulty, J. N. Peres, N. Bardine, W. M. R. van den Akker, and A. J. Durston Knockdown of the complete Hox paralogous group 1 leads to dramatic hindbrain and neural crest defects Development, June 15, 2005; 132(12): 2861 - 2871. [Abstract] [Full Text] [PDF]

				S. Chambeyron, N. R. Da Silva, K. A. Lawson, and W. A. Bickmore Nuclear re-organisation of the Hoxb complex during mouse embryonic development Development, May 1, 2005; 132(9): 2215 - 2223. [Abstract] [Full Text] [PDF]

				J. Bok, M. Bronner-Fraser, and D. K. Wu Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear Development, May 1, 2005; 132(9): 2115 - 2124. [Abstract] [Full Text] [PDF]

				E. Martinez-Ceballos, P. Chambon, and L. J. Gudas Differences in Gene Expression between Wild Type and Hoxa1 Knockout Embryonic Stem Cells after Retinoic Acid Treatment or Leukemia Inhibitory Factor (LIF) Removal J. Biol. Chem., April 22, 2005; 280(16): 16484 - 16498. [Abstract] [Full Text] [PDF]

				M. Schubert, J.-K. Yu, N. D. Holland, H. Escriva, V. Laudet, and L. Z. Holland Retinoic acid signaling acts via Hox1 to establish the posterior limit of the pharynx in the chordate amphioxus Development, January 1, 2005; 132(1): 61 - 73. [Abstract] [Full Text] [PDF]

				S. Remacle, L. Abbas, O. De Backer, N. Pacico, A. Gavalas, F. Gofflot, J. J. Picard, and R. Rezsohazy Loss of Function but No Gain of Function Caused by Amino Acid Substitutions in the Hexapeptide of Hoxa1 In Vivo Mol. Cell. Biol., October 1, 2004; 24(19): 8567 - 8575. [Abstract] [Full Text] [PDF]

				F. Cammas, M. Herzog, T. Lerouge, P. Chambon, and R. Losson Association of the transcriptional corepressor TIF1{beta} with heterochromatin protein 1 (HP1): an essential role for progression through differentiation Genes & Dev., September 1, 2004; 18(17): 2147 - 2160. [Abstract] [Full Text] [PDF]

				J. Briscoe and D. G. Wilkinson Establishing neuronal circuitry: Hox genes make the connection Genes & Dev., July 15, 2004; 18(14): 1643 - 1648. [Full Text] [PDF]

				B. R. Arenkiel, P. Tvrdik, G. O. Gaufo, and M. R. Capecchi Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry Genes & Dev., July 1, 2004; 18(13): 1539 - 1552. [Abstract] [Full Text] [PDF]

				C. T. Miller, L. Maves, and C. B. Kimmel moz regulates Hox expression and pharyngeal segmental identity in zebrafish Development, May 15, 2004; 131(10): 2443 - 2461. [Abstract] [Full Text] [PDF]

				Y. Murakami, M. Pasqualetti, Y. Takio, S. Hirano, F. M. Rijli, and S. Kuratani Segmental development of reticulospinal and branchiomotor neurons in lamprey: insights into the evolution of the vertebrate hindbrain Development, March 1, 2004; 131(5): 983 - 995. [Abstract] [Full Text] [PDF]

				M. Houle, J.-R. Sylvestre, and D. Lohnes Retinoic acid regulates a subset of Cdx1 function in vivo Development, December 29, 2003; 130(26): 6555 - 6567. [Abstract] [Full Text] [PDF]

				J. Jaszai, F. Reifers, A. Picker, T. Langenberg, and M. Brand Isthmus-to-midbrain transformation in the absence of midbrain-hindbrain organizer activity Development, December 29, 2003; 130(26): 6611 - 6623. [Abstract] [Full Text] [PDF]

				A. Gavalas, C. Ruhrberg, J. Livet, C. E. Henderson, and R. Krumlauf Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes Development, December 1, 2003; 130(23): 5663 - 5679. [Abstract] [Full Text] [PDF]

				G. O. Gaufo, K. R. Thomas, and M. R. Capecchi Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons Development, November 1, 2003; 130(21): 5191 - 5201. [Abstract] [Full Text] [PDF]

				E. L. Wiellette and H. Sive vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain Development, August 15, 2003; 130(16): 3821 - 3829. [Abstract] [Full Text] [PDF]

				S. Guidato, F. Prin, and S. Guthrie Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3 Development, July 1, 2003; 130(13): 2981 - 2996. [Abstract] [Full Text] [PDF]

				K. Niederreither, J. Vermot, I. L. Roux, B. Schuhbaur, P. Chambon, and P. Dolle The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system Development, June 1, 2003; 130(11): 2525 - 2534. [Abstract] [Full Text] [PDF]

				J. M. McClintock, M. A. Kheirbek, and V. E. Prince Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention Development, March 7, 2003; 129(10): 2339 - 2354. [Abstract] [Full Text] [PDF]

				J. Vermot, K. Niederreither, J.-M. Garnier, P. Chambon, and P. Dolle Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice PNAS, February 18, 2003; 100(4): 1763 - 1768. [Abstract] [Full Text] [PDF]

				N. Trokovic, R. Trokovic, P. Mai, and J. Partanen Fgfr1 regulates patterning of the pharyngeal region Genes & Dev., January 1, 2003; 17(1): 141 - 153. [Abstract] [Full Text] [PDF]

				M. M. Riccomagno, L. Martinu, M. Mulheisen, D. K. Wu, and D. J. Epstein Specification of the mammalian cochlea is dependent on Sonic hedgehog Genes & Dev., September 15, 2002; 16(18): 2365 - 2378. [Abstract] [Full Text] [PDF]

				O. Voiculescu, E. Taillebourg, C. Pujades, C. Kress, S. Buart, P. Charnay, and S. Schneider-Maunoury Hindbrain patterning: Krox20 couples segmentation and specification of regional identity Development, December 15, 2001; 128(24): 4967 - 4978. [Abstract] [Full Text] [PDF]

				M. Manzanares, S. Bel-Vialar, L. Ariza-McNaughton, E. Ferretti, H. Marshall, M. M. Maconochie, F. Blasi, and R. Krumlauf Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms Development, September 15, 2001; 128(18): 3595 - 3607. [Abstract] [Full Text] [PDF]

				Y. Zhao and S. S. Potter Functional specificity of the Hoxa13 homeobox Development, August 15, 2001; 128(16): 3197 - 3207. [Abstract] [Full Text] [PDF]