Aparicio, S., Morrison, A., Gould, A., Gilthorpe, J., Chaudhuri, C., Rigby, P., Krumlauf, R. and Brenner, S (1995). Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes. Proc. Natl. Acad. Sci. USA 92, 1684-1688.[Abstract/Free Full Text]
Beckers, J., Gerard, M. and Duboule, D (1996). Transgenic analysis of a potential Hoxd-11 limb regulatory element present in tetrapods and fish. Dev. Biol 180, 543-553.[Medline]
Davis, A. P. and Capecchi, M. R (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of Hoxd-11. Development 120, 2187-2198.[Abstract]
Davis, A. P., Witte, D. P., Hsieh-Li, H. M., Potter, S. S. and Capecchi, M. R (1995). Absence of radius and ulna in mice lacking Hoxa-11 and Hoxd-11. Nature 375, 791-795.[Medline]
Davis, A. P. and Capecchi, M. R (1996). A mutational analysis of the 5 HoxD genes: Dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.[Abstract]
Doetschman, T. C., Eistetter, H., Katz, M., Schmidt, W. and Kemler, R (1985). The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardum. J. Embryol. Exp. Morph 87, 27-45.[Medline]
Dolle, P., Dierich, A., LeMeur, M., Schimmang, T., Schuhbaur, B., Chambon, P. and Duboule, D (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75, 431-441.[Medline]
Duboule, D. and Morata, G (1994). Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet 10, 358-364.[Medline]
Dupe, V., Davenne, M., Brocard, J., Dolle, P., Mark, M., Dierich, A., Chambon, P. and Rijli, F. M (1997). In vivo functional analysis of the Hoxa-1 3retinoic acid response element (3 RARE). Development 124, 399-410.[Abstract]
Favier, B., Le Meur, M., Chambon, P. and Dolle, P (1995). Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc. Natl. Acad. Sci. USA 92, 310-314.[Abstract/Free Full Text]
Favier, B., Rijli, F. M., Fromental-Ramain, C., Fraulob, V., Chambon, P. and Dolle, P (1996). Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development 122, 449-460.[Abstract]
Frasch, M., Chen, X. and Lufkin, T (1995). Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila. Development 121, 957-974.[Abstract]
Fromental-Ramain, C., Warot, X., Lakkaraju, S., Favier, B., Haack, H., Birling, C., Dierich, A., Dolle, P. and Chambon, P (1996). Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 122, 461-472.[Abstract]
Fromental-Ramain, C., Warot, X., Messadecq, N., Le Meur, M., Dolle, P. and Chambon, P (1996). Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod. Development 122, 2997-3011.[Abstract]
Gerard, M., Duboule, D. and Z\207k\207ny, J (1993). Structure and activity of regulatory elements involved in the activation of the Hoxd-11 gene during late gastrulation. EMBO J 12, 3539-3550.[Medline]
Gerard, M., Chen, J. Y., Gronemeyer, H., Chambon, P., Duboule, D. and Z\207k\207ny, J (1996). In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. Genes Dev 10, 2326-2334.[Abstract/Free Full Text]
Gerard, M., Duboule, D. and Z\207k\207ny, J (1997). Interspecies exchange of a HoxD enhancer in vivo induces premature transcription and anterior shift of the sacrum. Dev. Biol 90, 32-40.
Goff, D. J. and Tabin, C. J (1997). Analysis of Hoxd-13 and Hoxd-11 misexpression in chicken limb buds reveal that Hox genes affect both bone condensation and growth. Development 124, 627-636.[Abstract]
Gould, A., Morrison, A., Sproat, G., White, R. A. and Krumlauf, R (1997). Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns. Genes Dev 11, 900-913.[Abstract/Free Full Text]
Haerry, T. E. and Gehring, W. J (1996). Intron of the mouse Hoxa-7 gene contains conserved homeodomain binding sites that can function as an enhancer element in Drosophila. Proc. Natl. Acad. Sci. USA 93, 13884-13889.[Abstract/Free Full Text]
Herault, Y., Fraudeau, N., Z\207k\207ny, J. and Duboule, D (1997). Ulnaless ( Ul ), a regulatory mutation inducing both loss-and gain-of-function of posterior Hoxd genes. Development 124, 3493-3500.[Abstract]
Herault, Y., S., Hraba-Renevey, S., van der Hoeven, F. and Duboule, D (1996). Function of the mouse Evx-2 gene in the morphogenesis of the vertebrate limbs. EMBO J 15, 6727-6738.[Medline]
Holland, P. W., Garcia-Fernandez, J., Williams, N. A., and Sidow, A (1994). Gene duplications and the origins of vertebrate development. Development 1994, 125-133.
Knittel, T., Kessel, M., Kim, M. H. and Gruss, P (1995). A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development. Development 121, 1077-1088.[Abstract]
Kondo, T., Dolle, P., Z\207k\207ny, J. and Duboule, D (1996). Function of posterior HoxD genes in the morphogenesis of the anal sphincter. Development 122, 2651-2659.[Abstract]
Kondo, T., Z\207k\207ny, J. and Duboule, D (1998). Control of colinearity in AbdB genes of the mouse HoxD complex. Molec. Cell 1, 289-300.
Kondo, T., Z\207k\207ny, J., Innis, J. W. and Duboule, D (1997). Of fingers, toes and penises. Nature 390, 29-.[Medline]
Marshall, H., Studer, M., Popperl, H., Aparicio, S., Kuroiwa, A., Brenner, S. and Krumlauf, R (1994). A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature 370, 567-571.[Medline]
Maconochie, M. K., Nonchev, S., Studer, M., Chan, S. K., Popperl, H., Sham, M. H., Mann, R. S. and Krumlauf, R (1997). Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1. Genes Dev 11, 1885-1895.[Abstract/Free Full Text]
Morrison, A., Ariza-McNaughton, L., Gould, A., Featherstone, M. and Krumlauf, R (1997). Hoxd-4 and regulation of the group 4 paralog genes. Development 124, 3135-3146.[Abstract]
Olson, E. N., Arnold, H.-H., Rigby, P. W. J. and Wold, B. J (1996). Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 85, 1-4.[Medline]
Peichel, C., Prabhakaran, B. and Vogt, T. F (1997). The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning. Development 124, 3481-3492.[Abstract]
Popperl, H., Bienz, M., Studer, M., Chan, S. K., Aparicio, S., Brenner, S., Mann, R. S. and Krumlauf, R (1995). Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81, 1031-1042.[Medline]
Rijli, F. M. and Chambon, P (1997). Genetic interactions of Hox genes in limb development: learning from coumpound mutant. Curr. Opin. Gen. Dev 7, 481-487.[Medline]
Shubin, N., Tabin, C., and Carroll, S (1997). Fossils, genes and the evolution of animal limbs. Nature 388, 639-648.[Medline]
Small, K. M. and Potter, S. S (1993). Homeotic transformation and limb defects in Hoxa-11 mutant mice. Genes Dev 7, 2318-2382.[Abstract/Free Full Text]
Sordino, P., van der Hoeven, F. and Duboule, D (1995). Hox gene expression in teleost fins and the origin of vertebrate digits. Nature 375, 678-681.[Medline]
van der Hoeven, F., Z\207k\207ny, J. and Duboule, D (1996). Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls. Cell 85, 1025-1035.[Medline]
Z\207k\207ny, J. and Duboule, D (1996). Synpolydactyly in mice with a targeted deficiency in the HoxD complex. Nature 384, 69-71.[Medline]
Z\207k\207ny, J., Gerard, M. and Duboule, D (1997). Deletion of a shared HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum. EMBO J 16, 4393-4402.[Medline]
