spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chen, Y.
Right arrow Articles by Hoffmann, F. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chen, Y.
Right arrow Articles by Hoffmann, F. M.
Affolter, M., Nellen, D., Nussbaumer, U. and Basler, K (1994). Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF-homologs during Drosophila embryogenesis. Development 120, 3105-3117.[Abstract]

Aono, A., Hazama, M., Notoya, K., Taketomi, S., Yamasaki, H., Tsukuda, R., Sasaki, S. and Fujisawa, Y (1995). Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7 heterodimer. Biochem. Biophys. Res. Commun 210, 670-677.[Medline]

Arora, K., Dai, H., Kazuko, S. G., Jamal, J., O'Connor, M. B., Letsou, A. and Warrior, R (1995). The Drosophilaschnurri gene acts in the Dpp/TGF-signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell 81, 781-790.[Medline]

Arora, K., Levine, M. S. and O'Connor, M. B (1994). The screw gene encodes a ubiquitously expressed member of the TGF-family required for specification of dorsal cell fates in the Drosophila embryo. Genes Dev 8, 2588-2601.[Abstract/Free Full Text]

Bienz, M (1994). Homeotic genes and positional signalling in the Drosophila viscera. Trends Genet 10, 22-26.[Medline]

Brook, W. J., Diaz-Benjumea, F. J. and Cohen, M. S (1996). Organizing spatial pattern in limb development. Annu. Rev. Cell Dev. Biol 12, 161-180.[Medline]

Brummel, T. J., Twombly, V., Marque, G., Wrana, J. L., Newfeld, S. J., Attisano, L., Massague, J., O'Connor, M. B. and Gelbart, W. M (1994). Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78, 251-261.[Medline]

Burke, R. and Basler, K (1996). Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development 122, 2261-2269.[Abstract]

Capovilla, M., Brandt, M. and Botas, J (1994). Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 76, 461-475.[Medline]

Childs, S. R., Wrana, J. L., Arora, K., Attisano, L., O'Connor, M. B. and Massague, J (1993). Identification of a Drosophila activin receptor. Proc. Natl. Acad. Sci. USA 90, 9475-9479.[Abstract/Free Full Text]

Derynck, R. and Zhang, Y (1996). Intracellular signalling: the mad way to do it. Curr. Biol 6, 1226-1229.[Medline]

Doctor, J. S., Jackson, P. D., Rashka, K. E., Visalli, M. and Hoffmann, F. M (1992). Sequence, biochemical characterization, and developmental expression of a new member of the TGF-superfamily in Drosophila melanogaster. Dev. Biol 151, 491-505.[Medline]

Eppert, K., Scherer, S. W., Ozcelik, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L. C., Bapat, B., Gallinger, S., Andrulis, I. L., Thomsen, G. H., Wrana, J. L. and Attisano, L (1996). MADR2 maps to 18q21 and encodes a TGF-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86, 543-552.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). Localized enhancement and repression of the activity of the TGF-family member, decapentaplegic , is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114, 583-597.[Abstract]

Gertler, F. B., Doctor, J. S. and Hoffmann, F. M (1990). Genetic suppression of mutations in the Drosophila abl Proto-oncogene homolog. Science 248, 857-860.[Abstract/Free Full Text]

Grieder, N. C., Nellen, D., Burke, R., Basler, K. and Affolter, M (1995). schnurri is required for Drosophila dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 81, 791-800.[Medline]

Hata, A., Lo, R. S., Wotton, D., Lagna, G. and Massague, J (1997). Mutations increasing autoinhibition inactivate tumour suppressors Samd2 and Smad4. Nature 388, 82-87.[Medline]

Hazama, M., Aono, A., Ueno, N. and Fujisawa, Y (1995). Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem. Biophys. Res. Commun 209, 859-866.[Medline]

Hogan, B. L (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10, 1580-1594.[Free Full Text]

Hou, X.S., Goldstein, E.S. and Perrimon, N (1997). Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes Dev 11, 1728-1737.[Abstract/Free Full Text]

Hursh, D. A., Padgett, R. W. and Gelbart, W. M (1993). Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila. Development 117, 1211-1222.[Abstract]

Immergluck, K., Lawrence, P. A. and Bienz, M (1990). Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62, 261-268.[Medline]

Jackson, P. D. and Hoffmann, F. M (1994). Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression. Developmental Dynamics 199, 28-44.[Medline]

Kim, J., Johnson, K., Chen, H. J., Carroll, S. and Laughon, A (1997). Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.[Medline]

Kingsley, D. M (1994). The TGF-superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8, 133-146.[Free Full Text]

Kingsley, D. M (1994). What do BMPs do in mammals? Clues from the mouse short-ear mutation. Trends Genet 10, 16-21.[Medline]

Letsou, A., Arora, K., Wrana, J. L., Simin, K., Twombly, V., Jamal, J., Staehling-Hampton, K., Hoffmann, F. M., Gelbart, W. M., Massague, J. and et al (1995). Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGFreceptor family. Cell 80, 899-908.[Medline]

Lyons, K. M., Hogan, B. L. and Robertson, E. J (1995). Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech. Dev 50, 71-83.[Medline]

Massague, J (1996). TGF-signaling: receptors, transducers, and Mad proteins. Cell 85, 947-950.[Medline]

Massague, J. and Weis-Garcia, F (1996). Serine/threonine kinase receptors: mediators of transforming growth factorfamily signals. Cancer Surv 27, 41-64.[Medline]

Masucci, J. D. and Hoffmann, F. M (1993). Identification of two regions from the Drosophila decapentaplegic gene required for embryonic midgut development and larval viability. Dev. Biol 159, 276-287.[Medline]

Masucci, J. D., Miltenberger, R. J. and Hoffmann, F. M (1990). Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3cis-regulatory elements. Genes Dev 4, 2011-2023.[Abstract/Free Full Text]

Miyazono, K., Ichijo, H. and C-H., H (1993). Transforming growth factor-latent forms, binding proteins and receptors. Growth Factors 8, 11-22.[Medline]

Nellen, D., Affolter, M. and Basler, K (1994). Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 78, 225-237.[Medline]

Newfeld, S. J., Chartoff, E. H., Graff, J. M., Melton, D. A. and Gelbart, W. M (1996). Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-responsive cells. Development 122, 2099-2108.[Abstract]

Newfeld, S. J., Mehra, A., Singer, M. A., Wrana, J. L., Attisano, L. and Gelbart, W. M (1997). Mothers against dpp participates in a DPP/TGF-responsive serine-threonine kinase signal transduction cascade. Development 124, 3167-3176.[Abstract]

Padgett, R. W., Wozney, J. M. and Gelbart, W. M (1993). Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 90, 2905-2909.[Abstract/Free Full Text]

Panganiban, G. E. F., Rashka, K. E., Neitzel, M. D. and Hoffmann, F. M (1990). Biochemical characterization of the Drosophila Dpp protein, a member of the transforming growth factor-family of growth factors. Mol. Cell. Biol 10, 2669-2677.[Abstract/Free Full Text]

Panganiban, G. E. F., Reuter, R., Scott, M. P. and Hoffmann, F. M (1990). A Drosophila growth factor homolog, decapentaplegic , regulates homeotic gene expression within and across germ layers during midgut morphogenesis. Development 110, 1041-1050.[Abstract/Free Full Text]

Penton, A., Chen, Y., Staehling-Hampton, K., Wrana, J. L., Attisano, L., Szidonya, J., Cassill, J. A., Massague, J. and Hoffmann, F. M (1994). Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell 78, 239-250.[Medline]

Raftery, L. A., Twombly, V., Wharton, K. and Gelbart, W. M (1995). Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics 139, 241-254.[Abstract]

Riesgo-Escovar, J.R. and Hafen, E (1997). Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes Dev 11, 1717-1727.[Abstract/Free Full Text]

Reuter, R., Panganiban, G. E. F., Hoffmann, F. M. and Scott, M. P (1990). Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 110, 1031-1040.[Abstract/Free Full Text]

Reuter, R. and Scott, M. P (1990). Expression and function of the homeoticgenes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development 109, 289-303.[Abstract]

Ruberte, E., Narty, T., Nellen, D., Affolter, M. and Basler, K (1995). An absolute requirement for both the type II and type I receptors, Punt and thickveins , for dpp signaling in vivo. Cell 80, 889-897.[Medline]

Sampath, T. K., Rashka, K. E., Doctor, J. S., Tucker, R. F. and Hoffmann, F. M (1993). Drosophila TGF-superfamily proteins induce endochondral bone formation in mammals. Proc. Natl. Acad. Sci USA 90, 6004-6008.[Abstract/Free Full Text]

Sekelsky, J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H. and Gelbart, W. M (1995). Genetic characterization and cloning of mothers against dpp , a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.[Abstract]

Shi, Y., Hata, A., Lo, R. S., Massague, J. and Pavletich, N. P (1997). A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87-93.[Medline]

Simon, M. A., Bowtell, D. D. L., Dodson, G. S., Laverty, T. R. and Rubin, G. M (1991). Ras 1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the Sevenless protein tyrosine kinase. Cell 67, 701-716.[Medline]

Singer, M. A., Penton, A., Twombly, V., Hoffmann, F. M. and Gelbart, W. M (1997). Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing. Development 124, 79-89.[Abstract]

Spencer, F. A., Hoffmann, F. M. and Gelbart, W. M (1982). Decapentaplegic : A gene complex affecting morphogenesis in Drosophila melanogaster. Cell 28, 451-461.[Medline]

St. Johnston, R. D. and Gelbart, W. D (1987). Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBO J 6, 2785-2791.[Medline]

Staehling-Hampton, K. and Hoffmann, F. M (1994). Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp and wingless , causing morphological defects. Dev. Biol 164, 502-512.[Medline]

Staehling-Hampton, K., Hoffmann, F. M., Baylies, M. K., Rushton, E. and Bate, M (1994). dpp induces mesodermal gene expression in Drosophila. Nature 372, 783-786.[Medline]

Staehling-Hampton, K., Laughon, A. S. and Hoffmann, F. M (1995). A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development 121, 3393-3403.[Abstract]

Struhl, G (1989). Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos. Nature 338, 741-744.[Medline]

Sun, B., Hursh, D. A., Jackson, D. and Beachy, P. A (1995). Ultrabithorax protein is necessary but not sufficient for full activation of decapentaplegic expression in the visceral mesoderm. EMBO J 14, 520-535.[Medline]

Suzuki, A., Kaneko, E., Maeda, J. and Ueno, N (1997). Mesoderm induction by BMP-4 and-7 heterodimers. Biochem. Biophys. Res. Commun 232, 153-156.[Medline]

Thuringer, F., Cohen, S. M. and Bienz, M (1993). Dissection of an indirect autoregulatory response of a homeotic Drosophila gene. EMBO J 12, 2419-2430.[Medline]

Thuringer, F., Cohen, S. M. and Bienz, M (1993). Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling. Proc. Natl. Acad. Sci. USA 90, 3899-3903.[Abstract/Free Full Text]

Tremml, G. and Bienz, M (1989). Homeotic gene expression in the visceral mesoderm of Drosophila embryos. EMBO J 8, 2677-2685.[Medline]

Twombly, V., Blackman, R. K., Jin, H., Graff, J. M., Padgett, R. W. and Gelbart, W. M (1996). The TGF-signaling pathway is essential for Drosophila oogenesis. Development 122, 1555-1565.[Abstract]

Wharton, K. A., Ray, R. P. and Gelbart, W. M (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.[Abstract]

Wharton, K. A., Thomsen, G. H. and Gelbart, W. M (1991). Drosophila 60A gene, a new TGF-\247 family member is closely related to human bone morphogenetic proteins. Proc. Natl. Acad. Sci. USA 88, 9214-9218.[Abstract/Free Full Text]

Wrana, J. L. and Pawson, T (1997). Mad about SMADs. Nature 388, 28-29.[Medline]

Xie, T., Finelli, A. L. and Padgett, R. W (1994). The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-superfamily. Science 263, 1756-1759.[Abstract/Free Full Text]




This article has been cited by other articles:


Home page
GeneticsHome page
J. Li, W. X. Li, and W. M. Gelbart
A Genetic Screen for Maternal-Effect Suppressors of decapentaplegic Identifies the eukaryotic translation initiation factor 4A in Drosophila
Genetics, December 1, 2005; 171(4): 1629 - 1641.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
N. T. Takaesu, E. Herbig, D. Zhitomersky, M. B. O'Connor, and S. J. Newfeld
DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila
Development, November 1, 2005; 132(21): 4883 - 4894.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
H Aoki, M Fujii, T Imamura, K Yagi, K Takehara, M Kato, and K Miyazono
Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction
J. Cell Sci., January 4, 2001; 114(8): 1483 - 1489.
[Abstract] [PDF]


Home page
DevelopmentHome page
H Bauer, Z Lele, G. Rauch, R Geisler, and M Hammerschmidt
The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo
Development, January 3, 2001; 128(6): 849 - 858.
[Abstract] [PDF]


Home page
DevelopmentHome page
K. Yu, S. Srinivasan, O. Shimmi, B. Biehs, K. E. Rashka, D. Kimelman, M. B. O'Connor, and E. Bier
Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity
Development, May 15, 2000; 127(10): 2143 - 2154.
[Abstract] [PDF]


Home page
Genes Dev.Home page
R. Fernandez, F. Takahashi, Z. Liu, R. Steward, D. Stein, and E. R. Stanley
The Drosophila Shark tyrosine kinase is required for embryonic dorsal closure
Genes & Dev., March 1, 2000; 14(5): 604 - 614.
[Abstract] [Full Text]


Home page
DevelopmentHome page
F Agnes, M Suzanne, and S Noselli
The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis
Development, January 12, 1999; 126(23): 5453 - 5462.
[Abstract] [PDF]


Home page
DevelopmentHome page
J Zeitlinger and D Bohmann
Thorax closure in Drosophila: involvement of Fos and the JNK pathway
Development, January 9, 1999; 126(17): 3947 - 3956.
[Abstract] [PDF]


Home page
DevelopmentHome page
M. Solloway and E. Robertson
Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup
Development, January 4, 1999; 126(8): 1753 - 1768.
[Abstract] [PDF]


Home page
Genes Dev.Home page
T. Brummel, S. Abdollah, T. E. Haerry, M. J. Shimell, J. Merriam, L. Raftery, J. L. Wrana, and M. B. O'Connor
The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development
Genes & Dev., January 1, 1999; 13(1): 98 - 111.
[Abstract] [Full Text]


Home page
DevelopmentHome page
S Krishna, L. Maduzia, and R. Padgett
Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
Development, January 1, 1999; 126(2): 251 - 260.
[Abstract] [PDF]


Home page
DevelopmentHome page
T. Haerry, O Khalsa, M. O'Connor, and K. Wharton
Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila
Development, January 10, 1998; 125(20): 3977 - 3987.
[Abstract] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chen, Y.
Right arrow Articles by Hoffmann, F. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chen, Y.
Right arrow Articles by Hoffmann, F. M.