Regulation of midline development by antagonism of lefty and nodal signaling

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				C. V. Esguerra, L. Nelles, L. Vermeire, A. Ibrahimi, A. D. Crawford, R. Derua, E. Janssens, E. Waelkens, P. Carmeliet, D. Collen, et al. Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination Development, December 15, 2007; 134(24): 4381 - 4393. [Abstract] [Full Text] [PDF]

				R. T. Rodriguez, J. M. Velkey, C. Lutzko, R. Seerke, D. B. Kohn, K. S. O'Shea, and M. T. Firpo Manipulation of OCT4 Levels in Human Embryonic Stem Cells Results in Induction of Differential Cell Types Experimental Biology and Medicine, November 1, 2007; 232(10): 1368 - 1380. [Abstract] [Full Text] [PDF]

				J. Schottenfeld, J. Sullivan-Brown, and R. D. Burdine Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw Development, April 15, 2007; 134(8): 1605 - 1615. [Abstract] [Full Text] [PDF]

				J. K. Takeuchi, H. Lickert, B. W. Bisgrove, X. Sun, M. Yamamoto, K. Chawengsaksophak, H. Hamada, H. J. Yost, J. Rossant, and B. G. Bruneau Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry PNAS, January 16, 2007; 104(3): 846 - 851. [Abstract] [Full Text] [PDF]

				N. Scamuffa, F. Calvo, M. Chretien, N. G. Seidah, and A.-M. Khatib Proprotein convertases: lessons from knockouts FASEB J, October 1, 2006; 20(12): 1954 - 1963. [Abstract] [Full Text] [PDF]

				J. J. Essner, J. D. Amack, M. K. Nyholm, E. B. Harris, and H. J. Yost Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut Development, March 15, 2005; 132(6): 1247 - 1260. [Abstract] [Full Text] [PDF]

				H. Hashimoto, M. Rebagliati, N. Ahmad, O. Muraoka, T. Kurokawa, M. Hibi, and T. Suzuki The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish Development, April 15, 2004; 131(8): 1741 - 1753. [Abstract] [Full Text] [PDF]

				T. Yabe, T. Shimizu, O. Muraoka, Y.-K. Bae, T. Hirata, H. Nojima, A. Kawakami, T. Hirano, and M. Hibi Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling Development, June 15, 2003; 130(12): 2705 - 2716. [Abstract] [Full Text] [PDF]

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				S. T. Dougan, R. M. Warga, D. A. Kane, A. F. Schier, and W. S. Talbot The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm Development, May 1, 2003; 130(9): 1837 - 1851. [Abstract] [Full Text] [PDF]

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				G. K. H. Przemeck, U. Heinzmann, J. Beckers, and M. Hrabe de Angelis Node and midline defects are associated with left-right development in Delta1 mutant embryos Development, January 1, 2003; 130(1): 3 - 13. [Abstract] [Full Text] [PDF]

				K. Hoshijima, J. E. Metherall, and D. J. Grunwald A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries Genes & Dev., October 1, 2002; 16(19): 2518 - 2529. [Abstract] [Full Text] [PDF]

				M. Poulain and T. Lepage Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish Development, January 11, 2002; 129(21): 4901 - 4914. [Abstract] [Full Text] [PDF]

				G. Hauptmann, H.-G. Belting, U. Wolke, K. Lunde, I. Soll, S. Abdelilah-Seyfried, V. Prince, and W. Driever spiel ohne grenzen/pou2 is required for zebrafish hindbrain segmentation Development, January 4, 2002; 129(7): 1645 - 1655. [Abstract] [Full Text] [PDF]

				L. Lowe, S Yamada, and M. Kuehn Genetic dissection of nodal function in patterning the mouse embryo Development, January 5, 2001; 128(10): 1831 - 1843. [Abstract] [PDF]

				X Yu, T. St Amand, S Wang, G Li, Y Zhang, Y. Hu, L Nguyen, M. Qiu, and Y. Chen Differential expression and functional analysis of Pitx2 isoforms in regulation of heart looping in the chick Development, January 3, 2001; 128(6): 1005 - 1013. [Abstract] [PDF]

				Y. Kikuchi, L. A. Trinh, J. F. Reiter, J. Alexander, D. Yelon, and D. Y.R. Stainier The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors Genes & Dev., May 15, 2000; 14(10): 1279 - 1289. [Abstract] [Full Text]

				D. B. Constam and E. J. Robertson SPC4/PACE4 regulates a TGFbeta signaling network during axis formation Genes & Dev., May 1, 2000; 14(9): 1146 - 1155. [Abstract] [Full Text]

				R. D. Burdine and A. F. Schier Conserved and divergent mechanisms in left-right axis formation Genes & Dev., April 1, 2000; 14(7): 763 - 776. [Full Text]

				J. Massagué and Y.-G. Chen Controlling TGF-beta signaling Genes & Dev., March 15, 2000; 14(6): 627 - 644. [Full Text]

				J. Liang, A Etheridge, L Hantsoo, A. Rubinstein, S. Nowak, J. Izpisua Belmonte, and M. Halpern Asymmetric nodal signaling in the zebrafish diencephalon positions the pineal organ Development, January 12, 2000; 127(23): 5101 - 5112. [Abstract] [PDF]

				B. Bisgrove, J. Essner, and H. Yost Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry Development, January 8, 2000; 127(16): 3567 - 3579. [Abstract] [PDF]

				S. Osada, Y Saijoh, A Frisch, C. Yeo, H Adachi, M Watanabe, M Whitman, H Hamada, and C. Wright Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1 Development, January 6, 2000; 127(11): 2503 - 2514. [Abstract] [PDF]

				K Gritsman, W. Talbot, and A. Schier Nodal signaling patterns the organizer Development, January 3, 2000; 127(5): 921 - 932. [Abstract] [PDF]

				A. Cheng, B Thisse, C Thisse, and C. Wright The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus Development, January 3, 2000; 127(5): 1049 - 1061. [Abstract] [PDF]

				J. Essner, W. Branford, J Zhang, and H. Yost Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms Development, January 3, 2000; 127(5): 1081 - 1093. [Abstract] [PDF]

				Y.-T. Yan, K. Gritsman, J. Ding, R. D. Burdine, J. D. Corrales, S. M. Price, W. S. Talbot, A. F. Schier, and M. M. Shen Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation Genes & Dev., October 1, 1999; 13(19): 2527 - 2537. [Abstract] [Full Text]