Andrikopoulos, K., Suzuki, H. R., Solursh, M. and Ramirez, F (1992). Localization of pro-alpha2 (V) collagen transcripts in the tissues of the developing mouse embryo. Dev. Dynamics 195, 113-120.[Medline]
Aubin, J. E., Liu, F., Malaval, L. and Gupta, A. K (1995). Osteoblast and chondroblast differentiation. Bone 17, 77-83.
Azpiazu, N. and Frasch, M (1993). tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev 7, 1325-1340.[Abstract/Free Full Text]
Azpiazu, N., Lawrence, P., Vincent, J.-P. and Frasch, M (1996). Segmentation and specification of the Drosophila mesoderm. Genes Dev 10, 3183-3194.[Abstract/Free Full Text]
Bell, D. M., Leung, K. K., Wheatley, S. C., Ng, L. J., Zhou, S., Ling, K. W., Sham, M. H., Koopman, P., Tam, P. P. and Cheah, K. S (1997). SOX9 directly regulates the type-II collagen gene. Nature Genet 16, 174-178.[Medline]
Bi, W., Deng, J. M., Zhang, Z., Behringer, R. R. and de Crombrugghe, B (1999). Sox9 is required for cartilage formation. Nat. Genet 22, 85-89.[Medline]
Borycki, A. G., Mendham, L. and Emerson, C. P., Jr (1998). Control of somite patterning by Sonic hedgehog and its downstream signal response genes. Development 125, 777-790.[Abstract]
Cancedda, R., Descalzi Cancedda, F. and Castagnola, P (1995). Chondrocyte differentiation. Int. Rev. Cytol 159, 265-358.[Medline]
Cohen, M. M., Jr (1998). Achondroplasia, hypochondroplasia and thanatophoric dysplasia: clinically related skeletal dysplasias that are also related at the molecular level. Int. J. Oral Maxillofac. Surg 27, 451-455.[Medline]
Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G. and Ornitz, D. M (1996). Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat. Genet 12, 390-397.[Medline]
Couly, G. F., Coltey, P. M. and Le Douarin, N. M (1992). The developmental fate of the cephalic mesoderm in quail-chick chimeras. Development 114, 1-15.[Abstract]
Couly, G. F., Coltey, P. M. and Le Douarin, N. M (1993). The triple origin of skull in higher vertebrates: a study in quail-chick chimeras. Development 117, 409-429.[Abstract]
D'Mello, S. R (1998). Molecular regulation of neuronal apoptosis. Curr. Top. Dev. Biol 39, 187-213.[Medline]
Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L. and Karsenty, G (1997). Osf2/Cbfa1 : a transcriptional activator of osteoblast differentiation. Cell 89, 747-754.[Medline]
Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P (1993). Sonic hedgehog , a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]
Frasch, M., Chen, X. and Lufkin, T (1995). Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila. Development 121, 957-974.[Abstract]
Furumoto, T. A., Miura, N., Akasaka, T., Mizutani-Koseki, Y., Sudo, H., Fukuda, K., Maekawa, M., Yuasa, S., Fu, Y., Moriya, H (1999). Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development. Dev. Biol 210, 15-29.[Medline]
Goldfarb, M (1990). The fibroblast growth factor family. Cell Growth & Differentiation 1, 439-445.[Medline]
Graff, J. M (1997). Embryonic patterning: To BMP or not to BMP, that is the question. Cell 89, 171-174.[Medline]
Green, M. C (1967). A defect of the splanchnic mesoderm caused by the mutant gene dominant hemimelia in the mouse. Dev. Biol 15, 62-89.[Medline]
Healy, C., Uwanogho, D. and Sharpe, P. T (1999). Regulation and role of Sox9 in cartilage formation. Dev. Dyn 215, 69-78.[Medline]
Hirsinger, E., Jouve, C., Malapert, P. and Pourquie, O (1998). Role of growth factors in shaping the developing somite. Mol. Cell. Endocrinol 140, 83-87.[Medline]
Iida, K., Koseki, H., Kakinuma, H., Kato, N., Mizutani-Koseki, Y., Ohuchi, H., Yoshioka, H., Noji, S., Kawamura, K., Kataoka, Y (1997). Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis. Development 124, 4627-4638.[Abstract]
Johnson, R. L., Laufer, E., Riddle, R. D. and Tabin, C (1994). Ectopic expression of sonic hedgehog alters dorsal-ventral patterning of somites. Cell 79, 1165-1173.[Medline]
Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y. H., Inada, M (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764.[Medline]
Koseki, H., Wallin, J., Witing, J., Mizutani, Y., Kispert, A., Ebensperger, C., Herrmann, B. G., Christ, B. and Balling, R (1993). A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae. Development 119, 649-660.[Abstract]
Lanske, B., Karaplis, A. C., Lee, K., Luz, A., Vortkamp, A., Pirro, A., Karperien, M., Defize, L. H. K., Ho, C., Mulligan, R. C (1996). PTH/PTHrP receptor in early development and Indian hedgehog -regulated bone growth. Science 273, 663-666.[Abstract]
Lassar, A. B. and Munsterberg, A. E (1996). The role of positive and negative signals in somite patterning. Curr. Opin. Neurobiol 6, 57-63.[Medline]
Lefebvre, V., Huang, W. D., Harley, V. R., Goodfellow, P. N. and deCrombrugghe, B (1997). SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha 1(II) collagen gene. Mol. Cell. Biol 17, 2336-2346.[Abstract]
Li, X., Wang, W. and Lufkin, T (1997). Dicistronic lacZ and alkaline phosphatase reporter constructs permit simultaneous histological analysis of expression from multiple transgenes. BioTechniques 23, 874-882.[Medline]
Liu, L., Khastgir, A., McCauley, J. M., Dunn, S. T., Morrissey, J. H., Christakos, S., Hughes, M. R. and Bourdeau, J. E (1996). RT-PCR microlocalization of mRNAs for calbindin D28k and vitamin D receptor in the murine nephron. Am. J. Physiol 270, 677-.
Lufkin, T., Lohnes, D., Mark, M., Dierich, A., Gorry, P., Gaub, M. P., LeMeur, M. and Chambon, P (1993). High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice. Proc. Natl. Acad. Sci. USA 90, 7225-7229.[Abstract/Free Full Text]
Lufkin, T., Mark, M., Hart, C. P., LeMeur, M. and Chambon, P (1992). Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene. Nature 359, 835-841.[Medline]
Lyons, K. M., Pelton, R. W. and Hogan, B. L (1989). Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor--like genes coordinately regulate aspects of embryonic development. Genes Dev 3, 1657-1668.[Abstract/Free Full Text]
Metsaranta, M., Garofalo, S., Smith, C., Niederreither, K., de Crombrugghe, B. and Vuorio, E (1995). Developmental expression of a type II collagen/-galactosidase fusion gene in transgenic mice. Dev. Dyn 204, 202-210.[Medline]
Milligan, C. E. and Schwartz, L. M (1997). Programmed cell death during animal development. Brit. Med. Bull 53, 570-590.[Abstract/Free Full Text]
Nagy, A., Moens, C., Ivanyi, E., Pawling, J., Gertsenstein, M., Hadjantonakis, A. K., Pirity, M. and Rossant, J (1998). Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Curr. Biol 8, 661-664.[Medline]
Naski, M. C., Colvin, J. S., Coffin, J. D. and Ornitz, D. M (1998). Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 125, 4977-4988.[Abstract]
Ng, L. J., Wheatley, S., Muscat, G. E. O., ConwayCampbell, J., Bowles, J., Wright, E., Bell, D. M., Tam, P. P. L., Cheah, K. S. E. and Koopman, P (1997). SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev. Biol 183, 108-121.[Medline]
Noden, D. M (1992). Vertebrate craniofacial development: novel approaches and new dilemmas. Curr. Opin. Genet. Dev 2, 576-581.[Medline]
Otto, F., Thornell, A. P., Crompton, T., Denzel, A., Gilmour, K. C., Rosewell, I. R., Stamp, G. W., Beddington, R. S., Mundlos, S., Olsen, B. R (1997). Cbfa1 , a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771.[Medline]
Pourquie, O., Fan, C. M., Coltey, M., Hirsinger, E., Watanabe, Y., Breant, C., Franciswest, P., Brickell, P., Tessier Lavigne, M. and Ledouarin, N. M (1996). Lateral and axial signals involved in avian somite patterning: a role for BMP4. Cell 84, 461-471.[Medline]
Sanders, E. J. and Wride, M. A (1995). Programmed cell death in development. Int. Rev. Cytol 163, 105-173.[Medline]
Sidow, A (1996). Gen(om)e duplications in the evolution of vertebrates. Curr. Opin. Gen. Dev 6, 715-722.[Medline]
Tiret, L., LeMouellic, H., Maury, M. and Brulet, P (1998). Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8 -deficient mice. Development 125, 279-291.[Abstract]
Tribioli, C., Frasch, M. and Lufkin, T (1997). Bapx1: an evolutionary-conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. Mech. Dev 65, 145-162.[Medline]
Tribioli, C. and Lufkin, T (1997). Molecular cloning, chromosomal mapping and developmental expression of BAPX1 , a novel human homeobox-containing gene homologous to Drosophila bagpipe. Gene 203, 225-233.[Medline]
Vortkamp, A., Lee, K., Lanske, B., Segre, G. V., Kronenberg, H. M. and Tabin, C. J (1996). Regulation of rate of cartilage differentiation by indian hedgehog and PTH-related protein. Science 273, 613-622.[Abstract]
Vortkamp, A., Pathi, S., Peretti, G. M., Caruso, E. M., Zaleske, D. J. and Tabin, C. J (1998). Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair. Mech. Dev 71, 65-76.[Medline]
Wang, W., VandeWater, T. and Lufkin, T (1998). Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development 125, 621-634.[Abstract]
Wang, Y., Spatz, M. K., Kannan, K., Hayk, H., Avivi, A., Gorivodsky, M.,Pines, M., Yayon, A., Lonai, P. and Givol, D (1999). A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc. Natl Acad. Sci. USA 96, 4455-4460.[Abstract/Free Full Text]
Wilkie, A. O (1997). Craniosynostosis: genes and mechanisms. Hum. Mol. Genet 6, 1647-1656.[Abstract/Free Full Text]
Wilm, B., Dahl, E., Peters, H., Balling, R. and Imai, K (1998). Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency. Proc. Natl Acad. Sci. USA 95, 8692-8697.[Abstract/Free Full Text]
Winnier, G. E., Hargett, L. and Hogan, B. L. M (1997). The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Gene Dev 11, 926-940.[Abstract/Free Full Text]
Wright, E., Hargrave, M. R., Christiansen, J., Cooper, L., Kun, J., Evans, T., Gangadharan, U., Greenfield, A. and Koopman, P (1995). The Sry -related gene Sox-9 is expressed during chondrogenesis in mouse embryos. Nat. Genet 9, 15-20.[Medline]
Yang, Y., Guillot, P., Boyd, Y., Lyon, M. F. and McMahon, A. P (1998). Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development 125, 3123-3132.[Abstract]
Zhao, Q., Eberspaecher, H., Lefebvre, V. and De Crombrugghe, B (1997). Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Dev. Dyn 209, 377-386.[Medline]
Zhou, G., Garofalo, S., Mukhopadhyay, K., Lefebvre, V., Smith, C. N., Eberspaecher, H. and De Crombrugghe, B (1995). A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. J. Cell Sci 108, 3677-3684.[Abstract]