Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5

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Blood, November 1, 2003; 102(9): 3196 - 3205.
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				N. El-Bizri, C. Guignabert, L. Wang, A. Cheng, K. Stankunas, C.-P. Chang, Y. Mishina, and M. Rabinovitch SM22{alpha}-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis Development, September 1, 2008; 135(17): 2981 - 2991. [Abstract] [Full Text] [PDF]

				A. Londesborough, K. Vaahtomeri, M. Tiainen, P. Katajisto, N. Ekman, T. Vallenius, and T. P. Makela LKB1 in endothelial cells is required for angiogenesis and TGF{beta}-mediated vascular smooth muscle cell recruitment Development, July 1, 2008; 135(13): 2331 - 2338. [Abstract] [Full Text] [PDF]

				J. Wu, C. S. Bohanan, J. C. Neumann, and J. B. Lingrel KLF2 Transcription Factor Modulates Blood Vessel Maturation through Smooth Muscle Cell Migration J. Biol. Chem., February 15, 2008; 283(7): 3942 - 3950. [Abstract] [Full Text] [PDF]

				Y. Suzuki, K. Montagne, A. Nishihara, T. Watabe, and K. Miyazono BMPs Promote Proliferation and Migration of Endothelial Cells via Stimulation of VEGF-A/VEGFR2 and Angiopoietin-1/Tie2 Signalling J. Biochem., February 1, 2008; 143(2): 199 - 206. [Abstract] [Full Text] [PDF]

				X. Pi, R. Ren, R. Kelley, C. Zhang, M. Moser, A. B. Bohil, M. DiVito, R. E. Cheney, and C. Patterson Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors J. Cell Biol., December 31, 2007; 179(7): 1569 - 1582. [Abstract] [Full Text] [PDF]

				L. J. McReynolds, S. Gupta, M. E. Figueroa, M. C. Mullins, and T. Evans Smad1 and Smad5 differentially regulate embryonic hematopoiesis Blood, December 1, 2007; 110(12): 3881 - 3890. [Abstract] [Full Text] [PDF]

				Y. Lan, B. Liu, H. Yao, F. Li, T. Weng, G. Yang, W. Li, X. Cheng, N. Mao, and X. Yang Essential Role of Endothelial Smad4 in Vascular Remodeling and Integrity Mol. Cell. Biol., November 1, 2007; 27(21): 7683 - 7692. [Abstract] [Full Text] [PDF]

				J. Astorga and P. Carlsson Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4 Development, October 15, 2007; 134(20): 3753 - 3761. [Abstract] [Full Text] [PDF]

				L. A. Compton, D. A. Potash, C. B. Brown, and J. V. Barnett Coronary Vessel Development Is Dependent on the Type III Transforming Growth Factor {beta} Receptor Circ. Res., October 12, 2007; 101(8): 784 - 791. [Abstract] [Full Text] [PDF]

				D. Liu, J. Wang, B. Kinzel, M. Mueller, X. Mao, R. Valdez, Y. Liu, and E. Li Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity Blood, September 1, 2007; 110(5): 1502 - 1510. [Abstract] [Full Text] [PDF]

				N. Y. Lee and G. C. Blobe The Interaction of Endoglin with beta-Arrestin2 Regulates Transforming Growth Factor-beta-mediated ERK Activation and Migration in Endothelial Cells J. Biol. Chem., July 20, 2007; 282(29): 21507 - 21517. [Abstract] [Full Text] [PDF]

				L. Umans, L. Cox, M. Tjwa, V. Bito, L. Vermeire, K. Laperre, K. Sipido, L. Moons, D. Huylebroeck, and A. Zwijsen Inactivation of Smad5 in Endothelial Cells and Smooth Muscle Cells Demonstrates that Smad5 Is Required for Cardiac Homeostasis Am. J. Pathol., May 1, 2007; 170(5): 1460 - 1472. [Abstract] [Full Text] [PDF]

				B. T. Zafonte, S. Liu, M. Lynch-Kattman, I. Torregroza, L. Benvenuto, M. Kennedy, G. Keller, and T. Evans Smad1 expands the hemangioblast population within a limited developmental window Blood, January 15, 2007; 109(2): 516 - 523. [Abstract] [Full Text] [PDF]

				S. Singbrant, J. L. Moody, U. Blank, G. Karlsson, L. Umans, A. Zwijsen, and S. Karlsson Smad5 is dispensable for adult murine hematopoiesis Blood, December 1, 2006; 108(12): 3707 - 3712. [Abstract] [Full Text] [PDF]

				N. W. Morrell Pulmonary Hypertension Due to BMPR2 Mutation: A New Paradigm for Tissue Remodeling? Proceedings of the ATS, November 1, 2006; 3(8): 680 - 686. [Abstract] [Full Text] [PDF]

				K.R. Barnett, C. Schilling, C.R. Greenfeld, D. Tomic, and J.A. Flaws Ovarian follicle development and transgenic mouse models Hum. Reprod. Update, September 1, 2006; 12(5): 537 - 555. [Abstract] [Full Text] [PDF]

				A. Hamik, B. Wang, and M. K. Jain Transcriptional Regulators of Angiogenesis Arterioscler. Thromb. Vasc. Biol., September 1, 2006; 26(9): 1936 - 1947. [Abstract] [Full Text] [PDF]

				E. A. Bosman, K. A. Lawson, J. Debruyn, L. Beek, A. Francis, L. Schoonjans, D. Huylebroeck, and A. Zwijsen Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels Development, September 1, 2006; 133(17): 3399 - 3409. [Abstract] [Full Text] [PDF]

				C. Park, K. Lavine, Y. Mishina, C.-X. Deng, D. M. Ornitz, and K. Choi Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation Development, September 1, 2006; 133(17): 3473 - 3484. [Abstract] [Full Text] [PDF]

				D. T. Fritz, S. Jiang, J. Xu, and M. B. Rogers A Polymorphism in a Conserved Posttranscriptional Regulatory Motif Alters Bone Morphogenetic Protein 2 (BMP2) RNA:Protein Interactions Mol. Endocrinol., July 1, 2006; 20(7): 1574 - 1586. [Abstract] [Full Text] [PDF]

				H. Lindskog, E. Athley, E. Larsson, S. Lundin, M. Hellstrom, and P. Lindahl New Insights to Vascular Smooth Muscle Cell and Pericyte Differentiation of Mouse Embryonic Stem Cells In Vitro Arterioscler. Thromb. Vasc. Biol., July 1, 2006; 26(7): 1457 - 1464. [Abstract] [Full Text] [PDF]

				Y. Zhan, A. Fujino, D. T. MacLaughlin, T. F. Manganaro, P. P. Szotek, N. A. Arango, J. Teixeira, and P. K. Donahoe Mullerian inhibiting substance regulates its receptor/SMAD signaling and causes mesenchymal transition of the coelomic epithelial cells early in Mullerian duct regression Development, June 15, 2006; 133(12): 2359 - 2369. [Abstract] [Full Text] [PDF]

				R. Li, A. Rosendahl, G. Brodin, A. M. Cheng, A. Ahgren, C. Sundquist, S. Kulkarni, T. Pawson, C.-H. Heldin, and R. L. Heuchel Deletion of Exon I of SMAD7 in Mice Results in Altered B Cell Responses. J. Immunol., June 1, 2006; 176(11): 6777 - 6784. [Abstract] [Full Text] [PDF]

				S. Gupta, H. Zhu, L. I. Zon, and T. Evans BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis Development, June 1, 2006; 133(11): 2177 - 2187. [Abstract] [Full Text] [PDF]

				J. L. Jadrich, M. B. O'Connor, and E. Coucouvanis The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development, April 1, 2006; 133(8): 1529 - 1541. [Abstract] [Full Text] [PDF]

				M. Ku, S. Howard, W. Ni, G. Lagna, and A. Hata OAZ Regulates Bone Morphogenetic Protein Signaling through Smad6 Activation J. Biol. Chem., February 24, 2006; 281(8): 5277 - 5287. [Abstract] [Full Text] [PDF]

				M. Maire, A. Florin, K. Kaszas, D. Regnier, P. Contard, E. Tabone, C. Mauduit, R. Bars, and M. Benahmed Alteration of Transforming Growth Factor-{beta} Signaling System Expression in Adult Rat Germ Cells with a Chronic Apoptotic Cell Death Process after Fetal Androgen Disruption Endocrinology, December 1, 2005; 146(12): 5135 - 5143. [Abstract] [Full Text] [PDF]

				M. Saura, C. Zaragoza, B. Herranz, M. Griera, L. Diez-Marques, D. Rodriguez-Puyol, and M. Rodriguez-Puyol Nitric Oxide Regulates Transforming Growth Factor-{beta} Signaling in Endothelial Cells Circ. Res., November 25, 2005; 97(11): 1115 - 1123. [Abstract] [Full Text] [PDF]

				J. Wang, N. Xu, X. Feng, N. Hou, J. Zhang, X. Cheng, Y. Chen, Y. Zhang, and X. Yang Targeted Disruption of Smad4 in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure Circ. Res., October 14, 2005; 97(8): 821 - 828. [Abstract] [Full Text] [PDF]