Targeted disruption of the murine junD gene results in multiple defects in male reproductive function

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Thepot, D.
	Articles by Yaniv, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Thepot, D.
	Articles by Yaniv, M.

Agarwal, S. K., Guru, S. C., Heppner, C., Erdos, M. R., Collins, R. M., Park, S. Y., Saggar, S., Chandrasekharappa, S. C., Collins, F. S., Spiegel, A. M. et al (1999). Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell 96, 143-152.[Medline]

Albert, M. and Roussel, C (1984). Strain differences in the concentration, motility and morphology of epididymal sperm in relation to puberty in mice. Int J Androl 7, 334-347.[Medline]

Alcivar, A. A., Hake, L. E., Kwon, Y. K. and Hecht, N. B (1991). junD mRNA expression differs from c-jun and junB mRNA expression during male germinal cell differentiation. Mol. Reprod. Dev 30, 187-193.[Medline]

Angel, P., Allegretto, E. A., Okino, S. T., Hattori, K., Boyle, W. J., Hunter, T. and Karin, M (1988). Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature 332, 166-171.[Medline]

Angel, P. and Karin, M (1991). The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 1072, 129-157.[Medline]

Baum, M. J., Brown, J. J., Kica, E., Rubin, B. S., Johnson, R. S. and Papaioannou, V. E (1994). Effect of a null mutation of the c-fos proto-oncogene on sexual behavior of male mice. Biol. Reprod 50, 1040-1048.[Abstract]

Blendy, J. A., Kaestner, K. H., Weinbauer, G. F., Nieschlag, E. and Schutz, G (1996). Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature 380, 162-165.[Medline]

Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K. and Tjian, R (1987). Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 238, 1386-1392.[Abstract/Free Full Text]

Bossy-Wetzel, E., Bakiri, L. and Yaniv, M (1997). Induction of apoptosis by the transcription factor c-Jun. EMBO J 16, 1695-1709.[Medline]

Brown, J. R., Ye, H., Bronson, R. T., Dikkes, P. and Greenberg, M. E (1996). A defect in nurturing in mice lacking the immediate early gene fosB. Cell 86, 297-309.[Medline]

Camus, A., Kress, C., Babinet, C. and Barra, J (1996). Unexpected behavior of a gene trap vector comprising a fusion between the Sh ble and the lacZ genes. Mol. Reprod. Dev 45, 255-263.[Medline]

Chiu, R., Angel, P. and Karin, M (1989). Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun. Cell 59, 979-986.[Medline]

Cohen, D. R., Vandermark, S. E., McGovern, J. D. and Bradley, M. P (1993). Transcriptional regulation in the testis: a role for transcription factor AP-1 complexes at various stages of spermatogenesis. Oncogene 8, 443-455.[Medline]

Elliott, D. J. and Cooke, H. J (1997). The molecular genetics of male infertility. BioEssays 19, 801-809.[Medline]

Grigoriadis, A. E., Wang, Z. Q., Cecchini, M. G., Hofstetter, W., Felix, R., Fleisch, H. A. and Wagner, E. F (1994). c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266, 443-448.[Abstract/Free Full Text]

Gruda, M. C., van Amsterdam, J., Rizzo, C. A., Durham, S. K., Lira, S. and Bravo, R (1996). Expression of FosB during mouse development: normal development of FosB knockout mice. Oncogene 12, 2177-2185.[Medline]

Hagaman, J. R., Moyer, J. S., Bachman, E. S., Sibony, M., Magyar, P. L., Welch, J. E., Smithies, O., Krege, J. H. and O'Brien, D. A (1998). Angiotensin-converting enzyme and male fertility. Proc. Natl. Acad. Sci. USA 95, 2552-2557.[Abstract/Free Full Text]

Hai, T. W., Liu, F., Coukos, W. J. and Green, M. R (1989). Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev 3, 2083-2090.[Abstract/Free Full Text]

Ham, J., Babij, C., Whitfield, J., Pfarr, C. M., Lallemand, D., Yaniv, M. and Rubin, L. L (1995). A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14, 927-939.[Medline]

Hilberg, F., Aguzzi, A., Howells, N. and Wagner, E. F (1993). c-jun is essential for normal mouse development and hepatogenesis. Nature 365, 179-181.[Medline]

Hirai, S. I., Ryseck, R. P., Mechta, F., Bravo, R. and Yaniv, M (1989). Characterization of junD: a new member of the jun proto-oncogene family. EMBO J 8, 1433-1439.[Medline]

Hummler, E., Cole, T. J., Blendy, J. A., Ganss, R., Aguzzi, A., Schmid, W., Beermann, F. and Schutz, G (1994). Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. Proc. Natl Acad. Sci. USA 91, 5647-5651.[Abstract/Free Full Text]

Johnson, R., Spiegelman, B., Hanahan, D. and Wisdom, R (1996). Cellular transformation and malignancy induced by ras require c-jun. Mol. Cell Biol 16, 4504-4511.[Abstract]

Johnson, R. S., Spiegelman, B. M. and Papaioannou, V (1992). Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71, 577-586.[Medline]

Johnson, R. S., van Lingen, B., Papaioannou, V. E. and Spiegelman, B. M (1993). A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev 7, 1309-1317.[Abstract/Free Full Text]

Kallunki, T., Deng, T., Hibi, M. and Karin, M (1996). c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 87, 929-939.[Medline]

Karnovsky, M (1971). Use of ferrocyanide-reduced osmium tetroxide in electron microscopy. J. Cell Biol 51, 284-.

Kastner, P., Mark, M., Leid, M., Gansmuller, A., Chin, W., Grondona, J. M., Decimo, D., Krezel, W., Dierich, A. and Chambon, P (1996). Abnormal spermatogenesis in RXRmutant mice. Genes Dev 10, 80-92.[Abstract/Free Full Text]

Kouzarides, T. and Ziff, E (1988). The role of the leucine zipper in the fos-jun interaction. Nature 336, 646-651.[Medline]

Kovary, K. and Bravo, R (1991). Expression of different Jun and Fos proteins during the G0-to-G1 transition in mouse fibroblasts: in vitro and in vivo associations. Mol. Cell Biol 11, 2451-2459.[Abstract/Free Full Text]

Kress, C., Vandormael, P. S., Baldacci, P., Cohen, T. M. and Babinet, C (1998). Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: establishment of ES cell lines bearing the omd conditional lethal mutation. Mamm. Genome 9, 998-1001.[Medline]

Lallemand, D., Spyrou, G., Yaniv, M. and Pfarr, C. M (1997). Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts. Oncogene 14, 819-830.[Medline]

Landschulz, W. H., Johnson, P. F. and McKnight, S. L (1988). The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240, 1759-1764.[Abstract/Free Full Text]

Lee, M. H., Williams, B. O., Mulligan, G., Mukai, S., Bronson, R. T., Dyson, N., Harlow, E. and Jacks, T (1996). Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev 10, 1621-1632.[Abstract/Free Full Text]

Mansour, S. L., Goddard, J. M. and Capecchi, M. R (1993). Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 117, 13-28.[Abstract]

Martin-Blanco, E (1997). Regulation of cell differentiation by the Drosophila Jun kinase cascade. Curr. Opin. Genet. Dev 7, 666-671.[Medline]

Mechta, F., Lallemand, D., Pfarr, C. M. and Yaniv, M (1997). Transformation by ras modifies AP1 composition and activity. Oncogene 14, 837-847.[Medline]

Nakabeppu, Y., Ryder, K. and Nathans, D (1988). DNA binding activities of three murine Jun proteins: stimulation by Fos. Cell 55, 907-915.[Medline]

Nantel, F., Monaco, L., Foulkes, N. S., Masquilier, D., LeMeur, M., Henriksen, K., Dierich, A., Parvinen, M. and Sassone-Corsi, P (1996). Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice. Nature 380, 159-162.[Medline]

Paylor, R., Johnson, R. S., Papaioannou, V., Spiegelman, B. M. and Wehner, J. M (1994). Behavioral assessment of c-fos mutant mice. Brain Res 651, 275-282.[Medline]

Pearse, R. n., Drolet, D. W., Kalla, K. A., Hooshmand, F., Bermingham, J. J. and Rosenfeld, M. G (1997). Reduced fertility in mice deficient for the POU protein sperm-1. Proc. Natl Acad. Sci. USA 94, 7555-7560.[Abstract/Free Full Text]

Pfarr, C. M., Mechta, F., Spyrou, G., Lallemand, D., Carillo, S. and Yaniv, M (1994). Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 76, 747-760.[Medline]

Reijo, R., Lee, T. Y., Salo, P., Alagappan, R., Brown, L. G., Rosenberg, M., Rozen, S., Jaffe, T., Straus, D., Hovatta, O (1995). Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nat. Genet 10, 383-393.[Medline]

Reimold, A. M., Grusby, M. J., Kosaras, B., Fries, J. W., Mori, R., Maniwa, S., Clauss, I. M., Collins, T., Sidman, R. L., Glimcher, M. J (1996). Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature 379, 262-265.[Medline]

Rudnicki, M. A., Schnegelsberg, P. N., Stead, R. H., Braun, T., Arnold, H. H. and Jaenisch, R (1993). MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75, 1351-1359.[Medline]

Rutberg, S. E., Saez, E., Glick, A., Dlugosz, A. A., Spiegelman, B. M. and Yuspa, S. H (1996). Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins. Oncogene 13, 167-176.[Medline]

Ryder, K., Lanahan, A., Perez, A. E. and Nathans, D (1989). jun-D: a third member of the jun gene family. Proc. Natl Acad. Sci. USA 86, 1500-1503.[Abstract/Free Full Text]

Ryseck, R. P., Hirai, S. I., Yaniv, M. and Bravo, R (1988). Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts. Nature 334, 535-537.[Medline]

Sah, V. P., Attardi, L. D., Mulligan, G. J., Williams, B. O., Bronson, R. T. and Jacks, T (1995). A subset of p53-deficient embryos exhibit exencephaly. Nat. Genet 10, 175-180.[Medline]

Sassone-Corsi, P., Ransone, L. J., Lamph, W. W. and Verma, I. M (1988). Direct interaction between fos and jun nuclear oncoproteins: role of the \324leucine zipper' domain. Nature 336, 692-695.[Medline]

Schorpp-Kistner, M., Wang, Z.-Q., Angel, P. and Wagner, E. F (1999). JunB is essential for mammalian placentation. EMBO J 18, 934-948.[Medline]

Schultz, R., Penttila, T. L., Parvinen, M., Persson, H., Hokfelt, T. and Pelto-Huikko, M (1995). Expression of immediate early genes in tubular cells of rat testis. Biol. Reprod 52, 1215-1226.[Abstract]

Sicinski, P., Donaher, J. L., Parker, S. B., Li, T., Fazeli, A., Gardner, H., Haslam, S. Z., Bronson, R. T., Elledge, S. J. and Weinberg, R. A (1995). Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82, 621-630.[Medline]

Smeal, T., Binetruy, B., Mercola, D. A., Birrer, M. and Karin, M (1991). Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354, 494-496.[Medline]

Supp, D. M., Witte, D. P., Branford, W. W., Smith, E. P. and Potter, S. S (1996). Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility. Dev. Biol 176, 284-299.[Medline]

Ting, X. and Spradling, A (1998). decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 94, 251-260.[Medline]

Wang, Z. Q., Ovitt, C., Grigoriadis, A. E., Mohle, S. U., Ruther, U. and Wagner, E. F (1992). Bone and haematopoietic defects in mice lacking c-fos. Nature 360, 741-745.[Medline]

Wilkinson, D. G., Bhatt, S., Ryseck, R. P. and Bravo, R (1989). Tissue-specific expression of c-jun and junB during organogenesis in the mouse. Development 106, 465-471.[Abstract]

Zhao, G. Q., Deng, K., Labosky, P. A., Liaw, L. and Hogan, B. L (1996). The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse. Genes Dev 10, 1657-1669.[Abstract/Free Full Text]

Zhao, G. Q., Liaw, L. and Hogan, B. L (1998). Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis. Development 125, 1103-1112.[Abstract]

This article has been cited by other articles:

J. J. Marden, Y. Zhang, F. D. Oakley, W. Zhou, M. Luo, H. P. Jia, P. B. McCray Jr., M. Yaniv, J. B. Weitzman, and J. F. Engelhardt
JunD Protects the Liver from Ischemia/Reperfusion Injury by Dampening AP-1 Transcriptional Activation
J. Biol. Chem., March 14, 2008; 283(11): 6687 - 6695.
[Abstract] [Full Text] [PDF]

I. KEHAT, T. HASIN, and A. ARONHEIM
The Role of Basic Leucine Zipper Protein-Mediated Transcription in Physiological and Pathological Myocardial Hypertrophy
Ann. N.Y. Acad. Sci., October 1, 2006; 1080(1): 97 - 109.
[Abstract] [Full Text] [PDF]

D. Escalier
Knockout mouse models of sperm flagellum anomalies
Hum. Reprod. Update, July 1, 2006; 12(4): 449 - 461.
[Abstract] [Full Text] [PDF]

D. Hilfiker-Kleiner, A. Hilfiker, M. Castellazzi, K. C. Wollert, C. Trautwein, H. Schunkert, and H. Drexler
JunD attenuates phenylephrine-mediated cardiomyocyte hypertrophy by negatively regulating AP-1 transcriptional activity
Cardiovasc Res, July 1, 2006; 71(1): 108 - 117.
[Abstract] [Full Text] [PDF]

D. Hilfiker-Kleiner, A. Hilfiker, K. Kaminski, A. Schaefer, J.-K. Park, K. Michel, A. Quint, M. Yaniv, J. B. Weitzman, and H. Drexler
Lack of JunD Promotes Pressure Overload-Induced Apoptosis, Hypertrophic Growth, and Angiogenesis in the Heart
Circulation, September 6, 2005; 112(10): 1470 - 1477.
[Abstract] [Full Text] [PDF]

J. Yan and B. F. Hales
Activator Protein-1 (AP-1) DNA Binding Activity Is Induced by Hydroxyurea in Organogenesis Stage Mouse Embryos
Toxicol. Sci., June 1, 2005; 85(2): 1013 - 1023.
[Abstract] [Full Text] [PDF]

N. Sofikitis, E. Pappas, A. Kawatani, D. Baltogiannis, D. Loutradis, N. Kanakas, D. Giannakis, F. Dimitriadis, K. Tsoukanelis, I. Georgiou, et al.
Efforts to create an artificial testis: culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment
Hum. Reprod. Update, May 1, 2005; 11(3): 229 - 259.
[Abstract] [Full Text] [PDF]

B. Li, M. Nair, D. R. Mackay, V. Bilanchone, M. Hu, M. Fallahi, H. Song, Q. Dai, P. E. Cohen, and X. Dai
Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression
Development, March 15, 2005; 132(6): 1463 - 1473.
[Abstract] [Full Text] [PDF]

J. Naito, H. Kaji, H. Sowa, G. N. Hendy, T. Sugimoto, and K. Chihara
Menin Suppresses Osteoblast Differentiation by Antagonizing the AP-1 Factor, JunD
J. Biol. Chem., February 11, 2005; 280(6): 4785 - 4791.
[Abstract] [Full Text] [PDF]

R. Ricci, U. Eriksson, G. Y. Oudit, R. Eferl, A. Akhmedov, I. Sumara, G. Sumara, Z. Kassiri, J.-P. David, L. Bakiri, et al.
Distinct functions of junD in cardiac hypertrophy and heart failure
Genes & Dev., January 15, 2005; 19(2): 208 - 213.
[Abstract] [Full Text] [PDF]

J. E. Shima, D. J. McLean, J. R. McCarrey, and M. D. Griswold
The Murine Testicular Transcriptome: Characterizing Gene Expression in the Testis During the Progression of Spermatogenesis
Biol Reprod, July 1, 2004; 71(1): 319 - 330.
[Abstract] [Full Text] [PDF]

L. Kenner, A. Hoebertz, T. Beil, N. Keon, F. Karreth, R. Eferl, H. Scheuch, A. Szremska, M. Amling, M. Schorpp-Kistner, et al.
Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects
J. Cell Biol., February 16, 2004; 164(4): 613 - 623.
[Abstract] [Full Text] [PDF]

J. O. Ward, L. G. Reinholdt, S. A. Hartford, L. A. Wilson, R. J. Munroe, K. J. Schimenti, B. J. Libby, M. O'Brien, J. K. Pendola, J. Eppig, et al.
Toward the Genetics of Mammalian Reproduction: Induction and Mapping of Gametogenesis Mutants in Mice
Biol Reprod, November 1, 2003; 69(5): 1615 - 1625.
[Abstract] [Full Text] [PDF]

S. K. Agarwal, E. A. Novotny, J. S. Crabtree, J. B. Weitzman, M. Yaniv, A. L. Burns, S. C. Chandrasekharappa, F. S. Collins, A. M. Spiegel, and S. J. Marx
Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter
PNAS, September 16, 2003; 100(19): 10770 - 10775.
[Abstract] [Full Text] [PDF]

S. P. M. Reddy and B. T. Mossman
Role and regulation of activator protein-1 in toxicant-induced responses of the lung
Am J Physiol Lung Cell Mol Physiol, December 1, 2002; 283(6): L1161 - L1178.
[Abstract] [Full Text] [PDF]

J.-P. David, K. Sabapathy, O. Hoffmann, M. H. Idarraga, and E. F. Wagner
JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms
J. Cell Sci., November 15, 2002; 115(22): 4317 - 4325.
[Abstract] [Full Text] [PDF]

T. M. Thway and M. W. Wolfe
An Activator Protein-1 Complex Mediates Epidermal Growth Factor Regulation of Equine Glycoprotein {alpha} Subunit Expression in Trophoblast Cells
Biol Reprod, September 1, 2002; 67(3): 972 - 980.
[Abstract] [Full Text] [PDF]

J. D. Short and C. M. Pfarr
Translational Regulation of the JunD Messenger RNA
J. Biol. Chem., August 30, 2002; 277(36): 32697 - 32705.
[Abstract] [Full Text] [PDF]

J. J. Andreucci, D. Grant, D. M. Cox, L. K. Tomc, R. Prywes, D. J. Goldhamer, N. Rodrigues, P.-A. Bedard, and J. C. McDermott
Composition and Function of AP-1 Transcription Complexes during Muscle Cell Differentiation
J. Biol. Chem., May 3, 2002; 277(19): 16426 - 16432.
[Abstract] [Full Text] [PDF]

A. Fleischmann, F. Hafezi, C. Elliott, C. E. Remé, U. Rüther, and E. F. Wagner
Fra-1 replaces c-Fos-dependent functions in mice
Genes & Dev., November 1, 2000; 14(21): 2695 - 2700.
[Abstract] [Full Text]

F. TERZI, M. BURTIN, and G. FRIEDLANDER
Using Transgenic Mice to Analyze the Mechanisms of Progression of Chronic Renal Failure
J. Am. Soc. Nephrol., November 1, 2000; 11(90002): 144S - 148.
[Abstract] [Full Text]

M Schreiber, Z. Wang, W Jochum, I Fetka, C Elliott, and E. Wagner
Placental vascularisation requires the AP-1 component fra1
Development, January 11, 2000; 127(22): 4937 - 4948.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Thepot, D.

Articles by Yaniv, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Thepot, D.

Articles by Yaniv, M.

				I. KEHAT, T. HASIN, and A. ARONHEIM The Role of Basic Leucine Zipper Protein-Mediated Transcription in Physiological and Pathological Myocardial Hypertrophy Ann. N.Y. Acad. Sci., October 1, 2006; 1080(1): 97 - 109. [Abstract] [Full Text] [PDF]

				D. Escalier Knockout mouse models of sperm flagellum anomalies Hum. Reprod. Update, July 1, 2006; 12(4): 449 - 461. [Abstract] [Full Text] [PDF]

				D. Hilfiker-Kleiner, A. Hilfiker, M. Castellazzi, K. C. Wollert, C. Trautwein, H. Schunkert, and H. Drexler JunD attenuates phenylephrine-mediated cardiomyocyte hypertrophy by negatively regulating AP-1 transcriptional activity Cardiovasc Res, July 1, 2006; 71(1): 108 - 117. [Abstract] [Full Text] [PDF]

				D. Hilfiker-Kleiner, A. Hilfiker, K. Kaminski, A. Schaefer, J.-K. Park, K. Michel, A. Quint, M. Yaniv, J. B. Weitzman, and H. Drexler Lack of JunD Promotes Pressure Overload-Induced Apoptosis, Hypertrophic Growth, and Angiogenesis in the Heart Circulation, September 6, 2005; 112(10): 1470 - 1477. [Abstract] [Full Text] [PDF]

				J. Yan and B. F. Hales Activator Protein-1 (AP-1) DNA Binding Activity Is Induced by Hydroxyurea in Organogenesis Stage Mouse Embryos Toxicol. Sci., June 1, 2005; 85(2): 1013 - 1023. [Abstract] [Full Text] [PDF]

				N. Sofikitis, E. Pappas, A. Kawatani, D. Baltogiannis, D. Loutradis, N. Kanakas, D. Giannakis, F. Dimitriadis, K. Tsoukanelis, I. Georgiou, et al. Efforts to create an artificial testis: culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment Hum. Reprod. Update, May 1, 2005; 11(3): 229 - 259. [Abstract] [Full Text] [PDF]

				B. Li, M. Nair, D. R. Mackay, V. Bilanchone, M. Hu, M. Fallahi, H. Song, Q. Dai, P. E. Cohen, and X. Dai Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression Development, March 15, 2005; 132(6): 1463 - 1473. [Abstract] [Full Text] [PDF]

				J. Naito, H. Kaji, H. Sowa, G. N. Hendy, T. Sugimoto, and K. Chihara Menin Suppresses Osteoblast Differentiation by Antagonizing the AP-1 Factor, JunD J. Biol. Chem., February 11, 2005; 280(6): 4785 - 4791. [Abstract] [Full Text] [PDF]

				R. Ricci, U. Eriksson, G. Y. Oudit, R. Eferl, A. Akhmedov, I. Sumara, G. Sumara, Z. Kassiri, J.-P. David, L. Bakiri, et al. Distinct functions of junD in cardiac hypertrophy and heart failure Genes & Dev., January 15, 2005; 19(2): 208 - 213. [Abstract] [Full Text] [PDF]

				J. E. Shima, D. J. McLean, J. R. McCarrey, and M. D. Griswold The Murine Testicular Transcriptome: Characterizing Gene Expression in the Testis During the Progression of Spermatogenesis Biol Reprod, July 1, 2004; 71(1): 319 - 330. [Abstract] [Full Text] [PDF]

				L. Kenner, A. Hoebertz, T. Beil, N. Keon, F. Karreth, R. Eferl, H. Scheuch, A. Szremska, M. Amling, M. Schorpp-Kistner, et al. Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects J. Cell Biol., February 16, 2004; 164(4): 613 - 623. [Abstract] [Full Text] [PDF]

				J. O. Ward, L. G. Reinholdt, S. A. Hartford, L. A. Wilson, R. J. Munroe, K. J. Schimenti, B. J. Libby, M. O'Brien, J. K. Pendola, J. Eppig, et al. Toward the Genetics of Mammalian Reproduction: Induction and Mapping of Gametogenesis Mutants in Mice Biol Reprod, November 1, 2003; 69(5): 1615 - 1625. [Abstract] [Full Text] [PDF]

				S. K. Agarwal, E. A. Novotny, J. S. Crabtree, J. B. Weitzman, M. Yaniv, A. L. Burns, S. C. Chandrasekharappa, F. S. Collins, A. M. Spiegel, and S. J. Marx Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter PNAS, September 16, 2003; 100(19): 10770 - 10775. [Abstract] [Full Text] [PDF]

				S. P. M. Reddy and B. T. Mossman Role and regulation of activator protein-1 in toxicant-induced responses of the lung Am J Physiol Lung Cell Mol Physiol, December 1, 2002; 283(6): L1161 - L1178. [Abstract] [Full Text] [PDF]

				J.-P. David, K. Sabapathy, O. Hoffmann, M. H. Idarraga, and E. F. Wagner JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms J. Cell Sci., November 15, 2002; 115(22): 4317 - 4325. [Abstract] [Full Text] [PDF]

				T. M. Thway and M. W. Wolfe An Activator Protein-1 Complex Mediates Epidermal Growth Factor Regulation of Equine Glycoprotein {alpha} Subunit Expression in Trophoblast Cells Biol Reprod, September 1, 2002; 67(3): 972 - 980. [Abstract] [Full Text] [PDF]

				J. D. Short and C. M. Pfarr Translational Regulation of the JunD Messenger RNA J. Biol. Chem., August 30, 2002; 277(36): 32697 - 32705. [Abstract] [Full Text] [PDF]

				J. J. Andreucci, D. Grant, D. M. Cox, L. K. Tomc, R. Prywes, D. J. Goldhamer, N. Rodrigues, P.-A. Bedard, and J. C. McDermott Composition and Function of AP-1 Transcription Complexes during Muscle Cell Differentiation J. Biol. Chem., May 3, 2002; 277(19): 16426 - 16432. [Abstract] [Full Text] [PDF]

				A. Fleischmann, F. Hafezi, C. Elliott, C. E. Remé, U. Rüther, and E. F. Wagner Fra-1 replaces c-Fos-dependent functions in mice Genes & Dev., November 1, 2000; 14(21): 2695 - 2700. [Abstract] [Full Text]

				F. TERZI, M. BURTIN, and G. FRIEDLANDER Using Transgenic Mice to Analyze the Mechanisms of Progression of Chronic Renal Failure J. Am. Soc. Nephrol., November 1, 2000; 11(90002): 144S - 148. [Abstract] [Full Text]

				M Schreiber, Z. Wang, W Jochum, I Fetka, C Elliott, and E. Wagner Placental vascularisation requires the AP-1 component fra1 Development, January 11, 2000; 127(22): 4937 - 4948. [Abstract] [PDF]