Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins

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Changing homeodomain residues 2 and 3 of Hoxa1 alters its activity in a cell-type and enhancer dependent manner
Nucleic Acids Res., June 15, 2002; 30(12): 2663 - 2668.
[Abstract] [Full Text] [PDF]

C. Fognani, C. Kilstrup-Nielsen, J. Berthelsen, E. Ferretti, V. Zappavigna, and F. Blasi
Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors
Nucleic Acids Res., May 1, 2002; 30(9): 2043 - 2051.
[Abstract] [Full Text] [PDF]

R. Maeda, A. Ishimura, K. Mood, E. K. Park, A. M. Buchberg, and I. O. Daar
Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos
PNAS, April 16, 2002; 99(8): 5448 - 5453.
[Abstract] [Full Text] [PDF]

S.-K. Choe, N. Vlachakis, and C. G. Sagerstrom
Meis family proteins are required for hindbrain development in the zebrafish
Development, January 2, 2002; 129(3): 585 - 595.
[Abstract] [Full Text] [PDF]

A. J. Waskiewicz, H. A. Rikhof, R. E. Hernandez, and C. B. Moens
Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning
Development, November 1, 2001; 128(21): 4139 - 4151.
[Abstract] [Full Text] [PDF]

M. Manzanares, S. Bel-Vialar, L. Ariza-McNaughton, E. Ferretti, H. Marshall, M. M. Maconochie, F. Blasi, and R. Krumlauf
Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms
Development, September 15, 2001; 128(18): 3595 - 3607.
[Abstract] [Full Text] [PDF]

N Vlachakis, S. Choe, and C. Sagerstrom
Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish
Development, January 4, 2001; 128(8): 1299 - 1312.
[Abstract] [PDF]

U. Thorsteinsdottir, E. Kroon, L. Jerome, F. Blasi, and G. Sauvageau
Defining Roles for HOX and MEIS1 Genes in Induction of Acute Myeloid Leukemia
Mol. Cell. Biol., January 1, 2001; 21(1): 224 - 234.
[Abstract] [Full Text]

M. Saleh, I. Rambaldi, X.-J. Yang, and M. S. Featherstone
Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases
Mol. Cell. Biol., November 15, 2000; 20(22): 8623 - 8633.
[Abstract] [Full Text]

J Liu and A Fire
Overlapping roles of two Hox genes and the exd ortholog ceh-20 in diversification of the C. elegans postembryonic mesoderm
Development, January 12, 2000; 127(23): 5179 - 5190.
[Abstract] [PDF]

S. Herzig, L. Fuzesi, and W. Knepel
Heterodimeric Pbx-Prep1 Homeodomain Protein Binding to the Glucagon Gene Restricting Transcription in a Cell Type-dependent Manner
J. Biol. Chem., September 1, 2000; 275(36): 27989 - 27999.
[Abstract] [Full Text] [PDF]

G. Di Rocco, A. Gavalas, H. Popperl, R. Krumlauf, F. Mavilio, and V. Zappavigna
The Recruitment of SOX/OCT Complexes and the Differential Activity of HOXA1 and HOXB1 Modulate the Hoxb1 Auto-regulatory Enhancer Function
J. Biol. Chem., June 1, 2001; 276(23): 20506 - 20515.
[Abstract] [Full Text] [PDF]

L. Pan, Y. Xie, T. A. Black, C. A. Jones, S. C. Pruitt, and K. W. Gross
An Abd-B Class HOX{middle dot}PBX Recognition Sequence Is Required for Expression from the Mouse Ren-1c Gene
J. Biol. Chem., August 24, 2001; 276(35): 32489 - 32494.
[Abstract] [Full Text] [PDF]

				X. Lampe, O. A. Samad, A. Guiguen, C. Matis, S. Remacle, J. J. Picard, F. M. Rijli, and R. Rezsohazy An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4 Nucleic Acids Res., June 1, 2008; 36(10): 3214 - 3225. [Abstract] [Full Text] [PDF]

				E. Kutejova, B. Engist, M. Self, G. Oliver, P. Kirilenko, and N. Bobola Six2 functions redundantly immediately downstream of Hoxa2 Development, April 15, 2008; 135(8): 1463 - 1470. [Abstract] [Full Text] [PDF]

				V. M. Diaz, S. Mori, E. Longobardi, G. Menendez, C. Ferrai, R. A. Keough, A. Bachi, and F. Blasi p160 Myb-Binding Protein Interacts with Prep1 and Inhibits Its Transcriptional Activity Mol. Cell. Biol., November 15, 2007; 27(22): 7981 - 7990. [Abstract] [Full Text] [PDF]

				H. Yoshioka, C. B. Geyer, J. L. Hornecker, K. T. Patel, and J. R. McCarrey In Vivo Analysis of Developmentally and Evolutionarily Dynamic Protein-DNA Interactions Regulating Transcription of the Pgk2 Gene during Mammalian Spermatogenesis Mol. Cell. Biol., November 15, 2007; 27(22): 7871 - 7885. [Abstract] [Full Text] [PDF]

				K.-Q. Gong, A. R. Yallowitz, H. Sun, G. R. Dressler, and D. M. Wellik A Hox-Eya-Pax Complex Regulates Early Kidney Developmental Gene Expression Mol. Cell. Biol., November 1, 2007; 27(21): 7661 - 7668. [Abstract] [Full Text] [PDF]

				E. Ferretti, J. C. Villaescusa, P. Di Rosa, L. C. Fernandez-Diaz, E. Longobardi, R. Mazzieri, A. Miccio, N. Micali, L. Selleri, G. Ferrari, et al. Hypomorphic Mutation of the TALE Gene Prep1 (pKnox1) Causes a Major Reduction of Pbx and Meis Proteins and a Pleiotropic Embryonic Phenotype Mol. Cell. Biol., August 1, 2006; 26(15): 5650 - 5662. [Abstract] [Full Text] [PDF]

				B. Noro, J. Culi, D. J. McKay, W. Zhang, and R. S. Mann Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax. Genes & Dev., June 15, 2006; 20(12): 1636 - 1650. [Abstract] [Full Text] [PDF]

				M. Zubair, S. Ishihara, S. Oka, K. Okumura, and K.-i. Morohashi Two-Step Regulation of Ad4BP/SF-1 Gene Transcription during Fetal Adrenal Development: Initiation by a Hox-Pbx1-Prep1 Complex and Maintenance via Autoregulation by Ad4BP/SF-1. Mol. Cell. Biol., June 1, 2006; 26(11): 4111 - 4121. [Abstract] [Full Text] [PDF]

				T. D. Capellini, G. Di Giacomo, V. Salsi, A. Brendolan, E. Ferretti, D. Srivastava, V. Zappavigna, and L. Selleri Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression Development, June 1, 2006; 133(11): 2263 - 2273. [Abstract] [Full Text] [PDF]

				A. A. Sharov, D. B. Dudekula, and M. S. H. Ko CisView: A Browser and Database of cis-regulatory Modules Predicted in the Mouse Genome DNA Res, January 1, 2006; 13(3): 123 - 134. [Abstract] [Full Text] [PDF]

				E. Ferretti, F. Cambronero, S. Tumpel, E. Longobardi, L. M. Wiedemann, F. Blasi, and R. Krumlauf Hoxb1 Enhancer and Control of Rhombomere 4 Expression: Complex Interplay between PREP1-PBX1-HOXB1 Binding Sites Mol. Cell. Biol., October 1, 2005; 25(19): 8541 - 8552. [Abstract] [Full Text] [PDF]

				A. Brendolan, E. Ferretti, V. Salsi, K. Moses, S. Quaggin, F. Blasi, M. L. Cleary, and L. Selleri A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny Development, July 1, 2005; 132(13): 3113 - 3126. [Abstract] [Full Text] [PDF]

				H. Huang, M. Rastegar, C. Bodner, S.-L. Goh, I. Rambaldi, and M. Featherstone MEIS C Termini Harbor Transcriptional Activation Domains That Respond to Cell Signaling J. Biol. Chem., March 18, 2005; 280(11): 10119 - 10127. [Abstract] [Full Text] [PDF]

				E. Kutejova, B. Engist, M. Mallo, B. Kanzler, and N. Bobola Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme Development, February 1, 2005; 132(3): 469 - 478. [Abstract] [Full Text] [PDF]

				P. J. Wermuth and A. M. Buchberg Meis1-mediated apoptosis is caspase dependent and can be suppressed by coexpression of HoxA9 in murine and human cell lines Blood, February 1, 2005; 105(3): 1222 - 1230. [Abstract] [Full Text] [PDF]

				K. Haller, I. Rambaldi, E. Daniels, and M. Featherstone Subcellular Localization of Multiple PREP2 Isoforms Is Regulated by Actin, Tubulin, and Nuclear Export J. Biol. Chem., November 19, 2004; 279(47): 49384 - 49394. [Abstract] [Full Text] [PDF]

				N. Beslu, J. Krosl, M. Laurin, N. Mayotte, K. R. Humphries, and G. Sauvageau Molecular interactions involved in HOXB4-induced activation of HSC self-renewal Blood, October 15, 2004; 104(8): 2307 - 2314. [Abstract] [Full Text] [PDF]

				J. W. Rhee, A. Arata, L. Selleri, Y. Jacobs, S. Arata, H. Onimaru, and M. L. Cleary Pbx3 Deficiency Results in Central Hypoventilation Am. J. Pathol., October 1, 2004; 165(4): 1343 - 1350. [Abstract] [Full Text] [PDF]

				M. W. Kankel, D. M. Duncan, and I. Duncan A Screen for Genes That Interact With the Drosophila Pair-Rule Segmentation Gene fushi tarazu Genetics, September 1, 2004; 168(1): 161 - 180. [Abstract] [Full Text] [PDF]

				O. A. Samad, M. J. Geisen, G. Caronia, I. Varlet, V. Zappavigna, J. Ericson, C. Goridis, and F. M. Rijli Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins Development, August 15, 2004; 131(16): 4071 - 4083. [Abstract] [Full Text] [PDF]

				V. Lecaudey, I. Anselme, F. Rosa, and S. Schneider-Maunoury The zebrafish Iroquois gene iro7 positions the r4/r5 boundary and controls neurogenesis in the rostral hindbrain Development, July 1, 2004; 131(13): 3121 - 3131. [Abstract] [Full Text] [PDF]

				P. Qin, J. M. Haberbusch, Z. Zhang, K. J. Soprano, and D. R. Soprano Pre-B Cell Leukemia Transcription Factor (PBX) Proteins Are Important Mediators for Retinoic Acid-dependent Endodermal and Neuronal Differentiation of Mouse Embryonal Carcinoma P19 Cells J. Biol. Chem., April 16, 2004; 279(16): 16263 - 16271. [Abstract] [Full Text] [PDF]

				B. T. Phillips, E. M. Storch, A. C. Lekven, and B. B. Riley A direct role for Fgf but not Wnt in otic placode induction Development, February 15, 2004; 131(4): 923 - 931. [Abstract] [Full Text] [PDF]

				G. Deflorian, N. Tiso, E. Ferretti, D. Meyer, F. Blasi, M. Bortolussi, and F. Argenton Prep1.1 has essential genetic functions in hindbrain development and cranial neural crest cell differentiation Development, February 1, 2004; 131(3): 613 - 627. [Abstract] [Full Text] [PDF]

				A. Gavalas, C. Ruhrberg, J. Livet, C. E. Henderson, and R. Krumlauf Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes Development, December 1, 2003; 130(23): 5663 - 5679. [Abstract] [Full Text] [PDF]

				E. Longobardi and F. Blasi Overexpression of PREP-1 in F9 Teratocarcinoma Cells Leads to a Functionally Relevant Increase of PBX-2 by Preventing Its Degradation J. Biol. Chem., October 3, 2003; 278(40): 39235 - 39241. [Abstract] [Full Text] [PDF]

				Z. Wang and R. S. Mann Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis Development, July 1, 2003; 130(13): 2853 - 2865. [Abstract] [Full Text] [PDF]

				M. F. Sanchez-Font, A. Bosch-Comas, R. Gonzalez-Duarte, and G. Marfany Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance Nucleic Acids Res., June 1, 2003; 31(11): 2769 - 2777. [Abstract] [Full Text] [PDF]

				S.-J. Kwak, B. T. Phillips, R. Heck, and B. B. Riley An expanded domain of fgf3 expression in the hindbrain of zebrafish valentino mutants results in mis-patterning of the otic vesicle Development, March 13, 2003; 129(22): 5279 - 5287. [Abstract] [Full Text] [PDF]

				L. Maves, W. Jackman, and C. B. Kimmel FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain Development, March 10, 2003; 129(16): 3825 - 3837. [Abstract] [Full Text] [PDF]