Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1

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Adachi, H., Saijoh, Y., Mochida, K., Ohishi, S., Hashiguchi, H., Hirao, A. and Hamada, H (1999). Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer. Genes Dev 13, 1589-1600.[Abstract/Free Full Text]

Agius, E., Oelgeschlager, M., Wessely, O., Kemp, C. and De Robertis, E. M (2000). Endodermal Nodal-related signals and mesoderm induction in Xenopus. Development 127, 1173-1183.[Abstract]

Baker, J. C., Beddington, R. S. and Harland, R. M (1999). Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development. Genes Dev 13, 3149-3159.[Abstract/Free Full Text]

Bisgrove, B. W., Essner, J. J. and Yost, H. J (1999). Regulation of midline development by antagonism of lefty and nodal signaling. Development 126, 3253-3262.[Abstract]

Candia, A. F., Watabe, T., Hawley, S. H. B., Onichtchouk, D., Zhang, Y., Derynck, R., Niehrs, C. and Cho, K. W. Y (1997). Cellular interpretation of multiple TGF-signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads. Development 124, 4467-4480.[Abstract]

Chen, X., Rubock, M. J. and Whitman, M (1996). A transcriptional partner for MAD proteins in TGF-signalling. Nature 383, 691-696.[Medline]

Chen, X., Weisberg, E., Fridmacher, V., Watanabe, M., Naco, G. and Whitman, M (1997). Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 389, 85-89.[Medline]

Cheng, A. M. S., Thisse, B., Thisse, C. and Wright, C. V. E (2000). Thelefty-related factor Xatv acts as a feedback inhibitor of Nodal signaling in mesoderm induction and L-R axis development in Xenopus. Development 127, 1049-1061.[Abstract]

Clements, D., Friday, R. V. and Woodland, H. R (1999). Mode of action of VegT in mesoderm and endoderm formation. Development 126, 4903-4911.[Abstract]

Collignon, J., Varlet, I. and Robertson, E. J (1996). Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381, 155-158.[Medline]

Conlon, F. L., Lyons, K. M., Takaesu, N., Barth, K. S., Kispert, A., Herrmann, B. and Robertson, E. J (1994). A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 120, 1919-1928.[Abstract]

Dyson, S. and Gurdon, J. B (1997). Activin signalling has a necessary function in Xenopus early development. Curr. Biol 7, 81-84.[Medline]

Erter, C. E., Solnica-Krezel, L. and Wright, C. V. E (1998). Zebrafish nodal-related 2 encodes an early mesendodermal inducer signaling from the extraembryonic yolk syncytial layer. Dev. Biol 204, 361-372.[Medline]

Feldman, B., Gates, M. A., Egan, E. S., Dougan, S. T., Rennebeck, G., Sirotkin, H. I., Schier, A. F. and Talbot, W. S (1998). Zebrafish organizer development and germ-layer formation require nodal-related signals. Nature 395, 181-185.[Medline]

Graff, J. M., Bansal, A. and Melton, D. A (1996). Xenopus Mad proteins transduce distinct subsets of signals for the TGFsuperfamily. Cell 85, 479-487.[Medline]

Green, J. B. A., New, H. V. and Smith, J. C (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71, 731-739.[Medline]

Green, J. B. A. and Smith, J. C (1990). Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature 347, 391-394.[Medline]

Gurdon, J. B., Harger, P., Mitchell, A. and Lemaire, P (1994). Activin signalling and response to a morphogen gradient. Nature 371, 487-492.[Medline]

Gurdon, J. B., Mitchell, A. and Mahony, D (1995). Direct and continuous assessment by cells of their position in a morphogen gradient. Nature 376, 520-521.[Medline]

Hansen, C. S., Marion, C. D., Steele, K., George, S. and Smith, W. C (1997). Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3. Development 124, 483-492.[Abstract]

Harland, R. and Gerhart, J (1997). Formation and function of Spemann's organizer. Ann. Rev. Cell Dev. Biol 13, 611-667.[Medline]

Henry, G. L., Brivanlou, I. H., Kessler, D. S., Hemmati-Brivanlou, A. and Melton, D. A (1996). TGF-signals and a prepattern in Xenopuslaevis endodermal development. Development 122, 1007-1015.[Abstract]

Horb, M. E. and Thomsen, G. H (1997). A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation. Development 124, 1689-1698.[Abstract]

Huang, H. C., Murtaugh, L. C., Vize, P. D. and Whitman, M (1995). Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo. EMBO J 14, 5965-5973.[Medline]

Hudson, C., Clements, D., Friday, R. V., Stott, D. and Woodland, H. R (1997). Xsox17and mediate endoderm formation in Xenopus. Cell 91, 397-405.[Medline]

Hyde, C. E. and Old, R. W (2000). Regulation of the early expression of the Xenopusnodal-related 1 gene, Xnr1. Development 127, 1221-1229.[Abstract]

Johnson, K., Kirkpatrick, H., Comer, A., Hoffmann, F. M. and Laughon, A (1999). Interaction of smad complexes with tripartite DNA-binding sites. J. Biol. Chem 274, 20709-20716.[Abstract/Free Full Text]

Jones, C. M., Kuehn, M. R., Hogan, B. L. M., Smith, J. C. and Wright, C. V. E (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.[Abstract]

Joseph, E. M. and Melton, D. A (1997). Xnr4 : a Xenopus nodal-related gene expressed in the Spemann organizer. Dev. Biol 184, 367-372.[Medline]

Joseph, E. M. and Melton, D. A (1998). Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos. Development 125, 2677-2685.[Abstract]

Kaufmann, E., Paul, H., Friedle, H., Metz, A., Scheucher, M., Clement, J. H. and Knochel, W (1996). Antagonistic actions of activin A and BMP-2/4 control dorsal lip-specific activation of the early response gene XFD-1 in Xenopuslaevis embryos. EMBO J 15, 6739-6749.[Medline]

Kimelman, D. and Griffin, K. J. P (1998). Mesoderm induction: a postmodern view. Cell 94, 419-421.[Medline]

Kofron, M., Demel, T., Xanthos, J., Lohr, J., Sun, B., Sive, H., Osada, S., Wright, C., Wylie, C. and Heasman, J (1999). Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFgrowth factors. Development 126, 5759-5770.[Abstract]

Kothary, R., Clapoff, S., Darling, S., Perry, M. D., Moran, L. A. and Rossant, J (1989). Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice. Development 105, 707-714.[Abstract/Free Full Text]

Labbe, E., Silvestri, C., Hoodless, P. A., Wrana, J. L. and Attisano, L (1998). Smad2 and Smad3 positively and negatively regulate TGF-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell 2, 109-120.

Latinkic, B. V., Umbhauer, M., Neal, K. A., Lerchner, W., Smith, J. C. and Cunliffe, V (1997). The XenopusBrachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev 11, 3265-3276.[Abstract/Free Full Text]

Levin, M., Johnson, R. L., Stern, C. D., Kuehn, M. and Tabin, C (1995). A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82, 803-814.[Medline]

Liu, B., Dou, C. L., Prabhu, L. and Lai, E (1999). FAST-2 is a mammalian winged-helix protein which mediates transforming growth factorsignals. Mol. Cell Biol 19, 424-430.[Abstract/Free Full Text]

Liu, F., Pouponnot, C. and Massague, J (1997). Dual role of the Smad4/DPC4 tumor suppressor in TGF-inducible transcriptional complexes. Genes Dev 11, 3157-3167.[Abstract/Free Full Text]

Lowe, L. A., Supp, D. M., Sampath, K., Yokoyama, T., Wright, C. V., Potter, S. S., Overbeek, P. and Kuehn, M. R (1996). Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature 381, 158-161.[Medline]

Lustig, K. D., Kroll, K., Sun, E., Ramos, R., Elmendorf, H. and Kirschner, M. W (1996). A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation. Development 122, 3275-3282.[Abstract]

Matzuk, M. M., Kumar, T. R., Vassalli, A., Bickenbach, J. R., Roop, D. R., Jaenisch, R. and Bradley, A (1995). Functional analysis of activins during mammalian development. Nature 374, 354-356.[Medline]

Meno, C., Gritsman, K., Ohishi, S., Ohfuji, Y., Heckscher, E., Mochida, K., Shimono, A., Kondoh, H., Talbot, W. S., Robertson, E. J (1999). Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Mol. Cell 4, 287-298.

Meno, C., Saijoh, Y., Fujii, H., Ikeda, M., Yokoyama, T., Yokoyama, M., Toyoda, Y. and Hamada, H (1996). Left-right asymmetric expression of the TGF-family member lefty in mouse embryos. Nature 381, 151-155.[Medline]

Meno, C., Shimono, A., Saijoh, Y., Yashiro, K., Mochida, K., Ohishi, S., Noji, S., Kondoh, H. and Hamada, H (1998). lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 94, 287-297.[Medline]

Norris, D. P. and Robertson, E. J (1999). Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis -acting regulatory elements. Genes Dev 13, 1575-1588.[Abstract/Free Full Text]

Osada, S. I. and Wright, C. V. E (1999). Xenopusnodal -related signaling is essential for mesendodermal patterning during early embryogenesis. Development 126, 3229-3240.[Abstract]

Piccolo, S., Agius, E., Leyns, L., Bhattacharyya, S., Grunz, H., Bouwmeester, T. and De Robertis, E. M (1999). The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals. Nature 397, 707-710.[Medline]

Rebagliati, M. R., Toyama, R., Fricke, C., Haffter, P. and Dawid, I. B (1998). Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev. Biol 199, 261-272.[Medline]

Rebagliati, M. R., Toyama, R., Haffter, P. and Dawid, I. B (1998). cyclops encodes a nodal-related factor involved in midline signaling. Proc. Natl. Acad. Sci. USA 95, 9932-9937.[Abstract/Free Full Text]

Rebbert, M. L. and Dawid, I. B (1997). Transcriptional regulation of the Xlim-1 gene by activin is mediated by an element in intron I. Proc. Natl. Acad. Sci. USA 94, 9717-9722.[Abstract/Free Full Text]

Rodriguez Esteban, C., Capdevila, J., Economides, A. N., Pascual, J., Ortiz, A. and Izpisua Belmonte, J. C (1999). The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature 401, 243-251.[Medline]

Saijoh, Y., Adachi, H., Mochida, K., Ohishi, S., Hirao, A. and Hamada, H (1999). Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2. Genes Dev 13, 259-269.[Abstract/Free Full Text]

Saijoh, Y., Adachi, H., Sakuma, R., Yeo, C. Y., Yashiro, K., Watanabe, M., Hashiguchi, H., Mochida, K., Ohishi, S., Kawabata, M (2000). Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol. Cell 5, 35-47.

Sampath, K., Cheng, A. M., Frisch, A. and Wright, C. V. E (1997). Functional differences among Xenopusnodal -relatedgenes in left-right axis determination. Development 124, 3293-3302.[Abstract]

Sampath, K., Rubinstein, A. L., Cheng, A. M., Liang, J. O., Fekany, K., Solnica-Krezel, L., Korzh, V., Halpern, M. E. and Wright, C. V. E (1998). Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature 395, 185-189.[Medline]

Schulte-Merker, S., Smith, J. C. and Dale, L (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?. EMBO J 13, 3533-3541.[Medline]

Smith, J (1995). Developmental biology. Angles on activin's absence. Nature 374, 311-312.[Medline]

Stennard, F., Carnac, G. and Gurdon, J. B (1996). The Xenopus T-box gene, Antipodean , encodes a vegetally localised maternal mRNA and can trigger mesoderm formation. Development 122, 4179-4188.[Abstract]

Thisse, C. and Thisse, B (1999). Antivin, a novel and divergent member of the TGFsuperfamily, negatively regulates mesoderm induction. Development 126, 229-240.[Abstract]

Varlet, I., Collignon, J., Norris, D. P. and Robertson, E. J (1997). Nodal signaling and axis formation in the mouse. Cold Spring Harb. Symp. Quant. Biol 62, 105-113.[Medline]

Watabe, T., Kim, S., Candia, A., Rothbacher, U., Hashimoto, C., Inoue, K. and Cho, K. W. Y (1995). Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev 9, 3038-3050.[Abstract/Free Full Text]

Watanabe, M. and Whitman, M (1999). FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo. Development 126, 5621-5634.[Abstract]

Weber, H., Holewa, B., Jones, E. A. and Ryffel, G. U (1996). Mesodermand endoderm differentiation in animal cap explants: identification of the HNF4-binding site as an activin A responsive element in the Xenopus HNF1promoter. Development 122, 1975-1984.[Abstract]

Weisberg, E., Winnier, G. E., Chen, X., Farnsworth, C. L., Hogan, B. L. and Whitman, M (1998). A mouse homologue of FAST-1 transduces TGFsuperfamily signals and is expressed during early embryogenesis. Mech. Dev 79, 17-27.[Medline]

Whitman, M (1998). Smads and early developmental signaling by the TGFsuperfamily. Genes Dev 12, 2445-2462.[Free Full Text]

Wylie, C., Kofron, M., Payne, C., Anderson, R., Hosobuchi, M., Joseph, E. and Heasman, J (1996). Maternal-catenin establishes a \324dorsal signal' in early Xenopus embryos. Development 122, 2987-2996.[Abstract]

Yasuo, H. and Lemaire, P (1999). A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos. Curr. Biol 9, 869-879.[Medline]

Yeo, C. Y., Chen, X. and Whitman, M (1999). The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis. J. Biol. Chem 274, 26584-26590.[Abstract/Free Full Text]

Yokouchi, Y., Vogan, K. J., Pearse, R. V. and Tabin, C. J (1999). Antagonistic signaling by Caronte , a novel Cerberus -related gene, establishes left-right asymmetric gene expression. Cell 98, 573-583.[Medline]

Zawel, L., Dai, J. L., Buckhaults, P., Zhou, S., Kinzler, K. W., Vogelstein, B. and Kern, S. E (1998). Human Smad3 and Smad4 are sequence-specific transcription activators. Mol. Cell 1, 611-617.

Zhang, J., Houston, D. W., King, M. L., Payne, C., Wylie, C. and Heasman, J (1998). The role of maternal VegT in establishing the primary germ layers in Xenopus embryos. Cell 94, 515-524.[Medline]

Zhang, J. and King, M. L (1996). XenopusVegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning. Development 122, 4119-4129.[Abstract]

Zhou, S., Zawel, L., Lengauer, C., Kinzler, K. W. and Vogelstein, B (1998). Characterization of human FAST-1 , a TGFand activin signal transducer. Mol. Cell 2, 121-127.

Zhou, X., Sasaki, H., Lowe, L., Hogan, B. L. M. and Kuehn, M. R (1993). Nodal is a novel TGF--like gene expressed in the mouse node during gastrulation. Nature 361, 543-547.[Medline]

Zhu, L., Marvin, M. J., Gardiner, A., Lassar, A. B., Mercola, M., Stern, C. D. and Levin, M (1999). Cerberus regulates left-right asymmetry of the embryonic head and heart. Curr. Biol 9, 931-938.[Medline]

Zorn, A. M., Butler, K. and Gurdon, J. B (1999). Anterior endomesoderm specification in Xenopus by Wnt/-catenin and TGF- signalling pathways. Dev. Biol 209, 282-297.[Medline]

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				H. Peeters, M. L. Voz, K. Verschueren, B. De Cat, H. Pendeville, B. Thienpont, A. Schellens, J. W. Belmont, G. David, W. J.M. Van De Ven, et al. Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling Hum. Mol. Genet., November 15, 2006; 15(22): 3369 - 3377. [Abstract] [Full Text] [PDF]

				A. Ishimura, J. K. Ng, M. Taira, S. G. Young, and S.-I. Osada Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor {beta} signaling Development, October 1, 2006; 133(19): 3919 - 3928. [Abstract] [Full Text] [PDF]

				A. L. Zamparini, T. Watts, C. E. Gardner, S. R. Tomlinson, G. I. Johnston, and J. M. Brickman Hex acts with {beta}-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal Development, September 15, 2006; 133(18): 3709 - 3722. [Abstract] [Full Text] [PDF]

				Y. Onuma, C.-Y. Yeo, and M. Whitman XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning Development, January 15, 2006; 133(2): 237 - 250. [Abstract] [Full Text] [PDF]

				J. Jullien and J. Gurdon Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction Genes & Dev., November 15, 2005; 19(22): 2682 - 2694. [Abstract] [Full Text] [PDF]

				D. W. Houston and C. Wylie Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning Development, November 1, 2005; 132(21): 4845 - 4855. [Abstract] [Full Text] [PDF]

				M. Ku, S. Y. Sokol, J. Wu, M. I. Tussie-Luna, A. L. Roy, and A. Hata Positive and Negative Regulation of the Transforming Growth Factor {beta}/Activin Target Gene goosecoid by the TFII-I Family of Transcription Factors Mol. Cell. Biol., August 15, 2005; 25(16): 7144 - 7157. [Abstract] [Full Text] [PDF]

				N. R. Dunn, C. H. Koonce, D. C. Anderson, A. Islam, E. K. Bikoff, and E. J. Robertson Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile Genes & Dev., January 1, 2005; 19(1): 152 - 163. [Abstract] [Full Text] [PDF]

				M. Kofron, H. Puck, H. Standley, C. Wylie, R. Old, M. Whitman, and J. Heasman New roles for FoxH1 in patterning the early embryo Development, October 15, 2004; 131(20): 5065 - 5078. [Abstract] [Full Text] [PDF]

				L. Zhang, H. Zhou, Y. Su, Z. Sun, H. Zhang, L. Zhang, Y. Zhang, Y. Ning, Y.-G. Chen, and A. Meng Zebrafish Dpr2 Inhibits Mesoderm Induction by Promoting Degradation of Nodal Receptors Science, October 1, 2004; 306(5693): 114 - 117. [Abstract] [Full Text] [PDF]

				H. Hashimoto, M. Rebagliati, N. Ahmad, O. Muraoka, T. Kurokawa, M. Hibi, and T. Suzuki The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish Development, April 15, 2004; 131(8): 1741 - 1753. [Abstract] [Full Text] [PDF]

				P. S. Kunwar, S. Zimmerman, J. T. Bennett, Y. Chen, M. Whitman, and A. F. Schier Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction Development, December 1, 2003; 130(23): 5589 - 5599. [Abstract] [Full Text] [PDF]

				S. Long, N. Ahmad, and M. Rebagliati The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry Development, June 1, 2003; 130(11): 2303 - 2316. [Abstract] [Full Text] [PDF]

				S. T. Dougan, R. M. Warga, D. A. Kane, A. F. Schier, and W. S. Talbot The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm Development, May 1, 2003; 130(9): 1837 - 1851. [Abstract] [Full Text] [PDF]

				M. Howell, G. J. Inman, and C. S. Hill A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements Development, March 8, 2003; 129(12): 2823 - 2834. [Abstract] [Full Text] [PDF]

				S. Shim, N. Bae, and J.-K. Han Bone morphogenetic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ) Nucleic Acids Res., July 15, 2002; 30(14): 3107 - 3117. [Abstract] [Full Text] [PDF]

				Y.-T. Yan, J.-J. Liu, Y. Luo, C. E, R. S. Haltiwanger, C. Abate-Shen, and M. M. Shen Dual Roles of Cripto as a Ligand and Coreceptor in the Nodal Signaling Pathway Mol. Cell. Biol., July 1, 2002; 22(13): 4439 - 4449. [Abstract] [Full Text] [PDF]

				C. Ring, S. Ogata, L. Meek, J. Song, T. Ohta, K. Miyazono, and K. W.Y. Cho The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling Genes & Dev., April 1, 2002; 16(7): 820 - 835. [Abstract] [Full Text] [PDF]

				P. M. Eimon and R. M. Harland Effects of heterodimerization and proteolytic processing on Derriere and Nodal activity: implications for mesoderm induction in Xenopus Development, January 7, 2002; 129(13): 3089 - 3103. [Abstract] [Full Text] [PDF]

				T. S. Yamamoto, C. Takagi, A. C. Hyodo, and N. Ueno Suppression of head formation by Xmsx-1 through the inhibition of intracellular nodal signaling Development, July 15, 2001; 128(14): 2769 - 2779. [Abstract] [Full Text] [PDF]

				M. Yamamoto, C. Meno, Y. Sakai, H. Shiratori, K. Mochida, Y. Ikawa, Y. Saijoh, and H. Hamada The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse Genes & Dev., May 15, 2001; 15(10): 1242 - 1256. [Abstract] [Full Text]

				P. A. Hoodless, M. Pye, C. Chazaud, E. Labbé, L. Attisano, J. Rossant, and J. L. Wrana FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse Genes & Dev., May 15, 2001; 15(10): 1257 - 1271. [Abstract] [Full Text]

				S Takahashi, C Yokota, K Takano, K Tanegashima, Y Onuma, J Goto, and M Asashima Two novel nodal-related genes initiate early inductive events in Xenopus Nieuwkoop center Development, January 12, 2000; 127(24): 5319 - 5329. [Abstract] [PDF]