Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes

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[Abstract] [Full Text] [PDF]

J. L. Kipp, S. M. Kilen, S. Bristol-Gould, T. K. Woodruff, and K. E. Mayo
Neonatal Exposure to Estrogens Suppresses Activin Expression and Signaling in the Mouse Ovary
Endocrinology, May 1, 2007; 148(5): 1968 - 1976.
[Abstract] [Full Text] [PDF]

C. Wang and S. K. Roy
Development of Primordial Follicles in the Hamster: Role of Estradiol-17{beta}
Endocrinology, April 1, 2007; 148(4): 1707 - 1716.
[Abstract] [Full Text] [PDF]

F. A. Syed, D. G. Fraser, T. C. Spelsberg, C. J. Rosen, A. Krust, P. Chambon, J. L. Jameson, and S. Khosla
Effects of Loss of Classical Estrogen Response Element Signaling on Bone in Male Mice
Endocrinology, April 1, 2007; 148(4): 1902 - 1910.
[Abstract] [Full Text] [PDF]

L. Ciarloni, S. Mallepell, and C. Brisken
Amphiregulin is an essential mediator of estrogen receptor {alpha} function in mammary gland development
PNAS, March 27, 2007; 104(13): 5455 - 5460.
[Abstract] [Full Text] [PDF]

N. L. Cho, S. H. Javid, A. M. Carothers, M. Redston, and M. M. Bertagnolli
Estrogen Receptors {alpha} and {beta} Are Inhibitory Modifiers of Apc-Dependent Tumorigenesis in the Proximal Colon of Min/+ Mice
Cancer Res., March 1, 2007; 67(5): 2366 - 2372.
[Abstract] [Full Text] [PDF]

A. M. Corbacho, J. P. Eiserich, L. A. Zuniga, G. Valacchi, and A. C. Villablanca
Compromised Aortic Vasoreactivity in Male Estrogen Receptor-{alpha}-Deficient Mice during Acute Lipopolysaccharide-Induced Inflammation
Endocrinology, March 1, 2007; 148(3): 1403 - 1411.
[Abstract] [Full Text] [PDF]

S. Kousteni, M. Almeida, L. Han, T. Bellido, R. L. Jilka, and S. C. Manolagas
Induction of Osteoblast Differentiation by Selective Activation of Kinase-Mediated Actions of the Estrogen Receptor
Mol. Cell. Biol., February 15, 2007; 27(4): 1516 - 1530.
[Abstract] [Full Text] [PDF]

H. A. Harris
Estrogen Receptor-{beta}: Recent Lessons from in Vivo Studies
Mol. Endocrinol., January 1, 2007; 21(1): 1 - 13.
[Abstract] [Full Text] [PDF]

G. Benoit, A. Cooney, V. Giguere, H. Ingraham, M. Lazar, G. Muscat, T. Perlmann, J.-P. Renaud, J. Schwabe, F. Sladek, et al.
International Union of Pharmacology. LXVI. Orphan Nuclear Receptors
Pharmacol. Rev., December 1, 2006; 58(4): 798 - 836.
[Abstract] [Full Text] [PDF]

M. Penza, C. Montani, A. Romani, P. Vignolini, B. Pampaloni, A. Tanini, M. L. Brandi, P. Alonso-Magdalena, A. Nadal, L. Ottobrini, et al.
Genistein Affects Adipose Tissue Deposition in a Dose-Dependent and Gender-Specific Manner
Endocrinology, December 1, 2006; 147(12): 5740 - 5751.
[Abstract] [Full Text] [PDF]

H. Hamada, M. K. Kim, A. Iwakura, M. Ii, T. Thorne, G. Qin, J. Asai, Y. Tsutsumi, H. Sekiguchi, M. Silver, et al.
Estrogen Receptors {alpha} and {beta} Mediate Contribution of Bone Marrow-Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction
Circulation, November 21, 2006; 114(21): 2261 - 2270.
[Abstract] [Full Text] [PDF]

J. E. O'Brien, T. J. Peterson, M. H. Tong, E.-J. Lee, L. E. Pfaff, S. C. Hewitt, K. S. Korach, J. Weiss, and J. L. Jameson
Estrogen-induced Proliferation of Uterine Epithelial Cells Is Independent of Estrogen Receptor {alpha} Binding to Classical Estrogen Response Elements
J. Biol. Chem., September 8, 2006; 281(36): 26683 - 26692.
[Abstract] [Full Text] [PDF]

K.R. Barnett, C. Schilling, C.R. Greenfeld, D. Tomic, and J.A. Flaws
Ovarian follicle development and transgenic mouse models
Hum. Reprod. Update, September 1, 2006; 12(5): 537 - 555.
[Abstract] [Full Text] [PDF]

M. Poutanen
Toward understanding the endocrine regulation of gonadal somatic cells.
Endocrinology, August 1, 2006; 147(8): 3662 - 3665.
[Full Text] [PDF]

J. F. Couse, M. M. Yates, K. F. Rodriguez, J. A. Johnson, D. Poirier, and K. S. Korach
The Intraovarian Actions of Estrogen Receptor-{alpha} Are Necessary to Repress the Formation of Morphological and Functional Leydig-Like Cells in the Female Gonad
Endocrinology, August 1, 2006; 147(8): 3666 - 3678.
[Abstract] [Full Text] [PDF]

M. Pannetier, S. Fabre, F. Batista, A. Kocer, L. Renault, G. Jolivet, B. Mandon-Pepin, C. Cotinot, R. Veitia, and E. Pailhoux
FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development.
J. Mol. Endocrinol., June 1, 2006; 36(3): 399 - 413.
[Abstract] [Full Text] [PDF]

J. Qiu, M. A. Bosch, S. C. Tobias, A. Krust, S. M. Graham, S. J. Murphy, K. S. Korach, P. Chambon, T. S. Scanlan, O. K. Ronnekleiv, et al.
A G-Protein-Coupled Estrogen Receptor Is Involved in Hypothalamic Control of Energy Homeostasis
J. Neurosci., May 24, 2006; 26(21): 5649 - 5655.
[Abstract] [Full Text] [PDF]

S. C. Hewitt, J. Collins, S. Grissom, K. Hamilton, and K. S. Korach
Estren Behaves as a Weak Estrogen Rather than a Nongenomic Selective Activator in the Mouse Uterus
Endo

				T. da Silva Faria, F. de Bittencourt Brasil, F. J B Sampaio, and C. da Fonte Ramos Maternal malnutrition during lactation alters the folliculogenesis and gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty J. Endocrinol., September 1, 2008; 198(3): 625 - 634. [Abstract] [Full Text] [PDF]

				C. Wang, E. R. Prossnitz, and S. K. Roy G Protein-Coupled Receptor 30 Expression Is Required for Estrogen Stimulation of Primordial Follicle Formation in the Hamster Ovary Endocrinology, September 1, 2008; 149(9): 4452 - 4461. [Abstract] [Full Text] [PDF]

				Y.-J. Chen, M.-T. Lee, H.-C. Yao, P.-W. Hsiao, F.-C. Ke, and J.-J. Hwang Crucial Role of Estrogen Receptor-{alpha} Interaction with Transcription Coregulators in Follicle-Stimulating Hormone and Transforming Growth Factor {beta}1 Up-Regulation of Steroidogenesis in Rat Ovarian Granulosa Cells Endocrinology, September 1, 2008; 149(9): 4658 - 4668. [Abstract] [Full Text] [PDF]

				F. Yasuhara, G. R. O. Gomes, E. R. Siu, C. I. Suenaga, E. Marostica, C. S. Porto, and M. F. M. Lazari Effects of the Antiestrogen Fulvestrant (ICI 182,780) on Gene Expression of the Rat Efferent Ductules Biol Reprod, September 1, 2008; 79(3): 432 - 441. [Abstract] [Full Text] [PDF]

				C. Glidewell-Kenney, J. Weiss, L. A. Hurley, J. E. Levine, and J. L. Jameson Estrogen Receptor {alpha} Signaling Pathways Differentially Regulate Gonadotropin Subunit Gene Expression and Serum Follicle-Stimulating Hormone in the Female Mouse Endocrinology, August 1, 2008; 149(8): 4168 - 4176. [Abstract] [Full Text] [PDF]

				B. Calippe, V. Douin-Echinard, M. Laffargue, H. Laurell, V. Rana-Poussine, B. Pipy, J.-C. Guery, F. Bayard, J.-F. Arnal, and P. Gourdy Chronic Estradiol Administration In Vivo Promotes the Proinflammatory Response of Macrophages to TLR4 Activation: Involvement of the Phosphatidylinositol 3-Kinase Pathway J. Immunol., June 15, 2008; 180(12): 7980 - 7988. [Abstract] [Full Text] [PDF]

				K. W. Sinkevicius, J. E. Burdette, K. Woloszyn, S. C. Hewitt, K. Hamilton, S. L. Sugg, K. A. Temple, F. E. Wondisford, K. S. Korach, T. K. Woodruff, et al. An Estrogen Receptor-{alpha} Knock-In Mutation Provides Evidence of Ligand-Independent Signaling and Allows Modulation of Ligand-Induced Pathways in Vivo Endocrinology, June 1, 2008; 149(6): 2970 - 2979. [Abstract] [Full Text] [PDF]

				V. M. Miller and S. P. Duckles Vascular Actions of Estrogens: Functional Implications Pharmacol. Rev., June 1, 2008; 60(2): 210 - 241. [Abstract] [Full Text] [PDF]

				N. D. Ullrich, A. Krust, P. Collins, and K. T. MacLeod Genomic deletion of estrogen receptors ER{alpha} and ER{beta} does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes Am J Physiol Heart Circ Physiol, June 1, 2008; 294(6): H2421 - H2427. [Abstract] [Full Text] [PDF]

				Q. Gao and T. L. Horvath Cross-talk between estrogen and leptin signaling in the hypothalamus Am J Physiol Endocrinol Metab, May 1, 2008; 294(5): E817 - E826. [Abstract] [Full Text] [PDF]

				V. Douin-Echinard, S. Laffont, C. Seillet, L. Delpy, A. Krust, P. Chambon, P. Gourdy, J.-F. Arnal, and J.-C. Guery Estrogen Receptor {alpha}, but Not {beta}, Is Required for Optimal Dendritic Cell Differentiation and CD40-Induced Cytokine Production J. Immunol., March 15, 2008; 180(6): 3661 - 3669. [Abstract] [Full Text] [PDF]

				A. Billon, S. Lehoux, L. Lam Shang Leen, H. Laurell, C. Filipe, V. Benouaich, L. Brouchet, C. Dessy, P. Gourdy, A.-P. Gadeau, et al. The Estrogen Effects on Endothelial Repair and Mitogen-Activated Protein Kinase Activation Are Abolished in Endothelial Nitric-Oxide (NO) Synthase Knockout Mice, but Not by NO Synthase Inhibition by N-Nitro-L-arginine Methyl Ester Am. J. Pathol., March 1, 2008; 172(3): 830 - 838. [Abstract] [Full Text] [PDF]

				M. C. Antal, A. Krust, P. Chambon, and M. Mark Sterility and absence of histopathological defects in nonreproductive organs of a mouse ER{beta}-null mutant PNAS, February 19, 2008; 105(7): 2433 - 2438. [Abstract] [Full Text] [PDF]

				M. C. Gieske, H. J. Kim, S. J. Legan, Y. Koo, A. Krust, P. Chambon, and C. Ko Pituitary Gonadotroph Estrogen Receptor-{alpha} Is Necessary for Fertility in Females Endocrinology, January 1, 2008; 149(1): 20 - 27. [Abstract] [Full Text] [PDF]

				J. L. Kipp, S. M. Kilen, T. K. Woodruff, and K. E. Mayo Activin Regulates Estrogen Receptor Gene Expression in the Mouse Ovary J. Biol. Chem., December 14, 2007; 282(50): 36755 - 36765. [Abstract] [Full Text] [PDF]

				H. J. Kim, M. C Gieske, S. Hudgins, B. G. Kim, A. Krust, P. Chambon, and C. Ko Estrogen receptor {alpha}-induced cholecystokinin type A receptor expression in the female mouse pituitary J. Endocrinol., December 1, 2007; 195(3): 393 - 405. [Abstract] [Full Text] [PDF]

				M. A. McDevitt, C. Glidewell-Kenney, J. Weiss, P. Chambon, J. L. Jameson, and J. E. Levine Estrogen Response Element-Independent Estrogen Receptor (ER)-{alpha} Signaling Does Not Rescue Sexual Behavior but Restores Normal Testosterone Secretion in Male ER{alpha} Knockout Mice Endocrinology, November 1, 2007; 148(11): 5288 - 5294. [Abstract] [Full Text] [PDF]

				R. Shao, E. Egecioglu, B. Weijdegard, J. J. Kopchick, J. Fernandez-Rodriguez, N. Andersson, and H. Billig Dynamic regulation of estrogen receptor-{alpha} isoform expression in the mouse fallopian tube: mechanistic insight into estrogen-dependent production and secretion of insulin-like growth factors Am J Physiol Endocrinol Metab, November 1, 2007; 293(5): E1430 - E1442. [Abstract] [Full Text] [PDF]

				C. E. Andreescu, B. A. Milojkovic, E. D. Haasdijk, P. Kramer, F. H. De Jong, A. Krust, C. I. De Zeeuw, and M. T. G. De Jeu Estradiol Improves Cerebellar Memory Formation by Activating Estrogen Receptor {beta} J. Neurosci., October 3, 2007; 27(40): 10832 - 10839. [Abstract] [Full Text] [PDF]

				Y. Feng, D. Manka, K.-U. Wagner, and S. A. Khan Estrogen receptor-{alpha} expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice PNAS, September 11, 2007; 104(37): 14718 - 14723. [Abstract] [Full Text] [PDF]

				B. J. McMillan and C. A. Bradfield The Aryl Hydrocarbon Receptor sans Xenobiotics: Endogenous Function in Genetic Model Systems Mol. Pharmacol., September 1, 2007; 72(3): 487 - 498. [Abstract] [Full Text] [PDF]

				J. I. Aguirre, L. I. Plotkin, A. R. Gortazar, M. M. Millan, C. A. O'Brien, S. C. Manolagas, and T. Bellido A Novel Ligand-independent Function of the Estrogen Receptor Is Essential for Osteocyte and Osteoblast Mechanotransduction J. Biol. Chem., August 31, 2007; 282(35): 25501 - 25508. [Abstract] [Full Text] [PDF]

				L. K. Saxon, A. G. Robling, A. B. Castillo, S. Mohan, and C. H. Turner The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor-beta Am J Physiol Endocrinol Metab, August 1, 2007; 293(2): E484 - E491. [Abstract] [Full Text] [PDF]

				V. J. Armstrong, M. Muzylak, A. Sunters, G. Zaman, L. K. Saxon, J. S. Price, and L. E. Lanyon Wnt/beta-Catenin Signaling Is a Component of Osteoblastic Bone Cell Early Responses to Load-bearing and Requires Estrogen Receptor {alpha} J. Biol. Chem., July 13, 2007; 282(28): 20715 - 20727. [Abstract] [Full Text] [PDF]

				R. Shao, B. Weijdegard, J. Fernandez-Rodriguez, E. Egecioglu, C. Zhu, N. Andersson, A. Thurin-Kjellberg, C. Bergh, and H. Billig Ciliated epithelial-specific and regional-specific expression and regulation of the estrogen receptor-beta2 in the fallopian tubes of immature rats: a possible mechanism for estrogen-mediated transport process in vivo Am J Physiol Endocrinol Metab, July 1, 2007; 293(1): E147 - E158. [Abstract] [Full Text] [PDF]

				R. O'Lone, K. Knorr, I. Z. Jaffe, M. E. Schaffer, P. G. V. Martini, R. H. Karas, J. Bienkowska, M. E. Mendelsohn, and U. Hansen Estrogen Receptors {alpha} and {beta} Mediate Distinct Pathways of Vascular Gene Expression, Including Genes Involved in Mitochondrial Electron Transport and Generation of Reactive Oxygen Species Mol. Endocrinol., June 1, 2007; 21(6): 1281 - 1296. [Abstract] [Full Text] [PDF]

				S. Yu, X. Wang, C.-F. Ng, S. Chen, and F. L. Chan ERR{gamma} Suppresses Cell Proliferation and Tumor Growth of Androgen-Sensitive and Androgen-Insensitive Prostate Cancer Cells and Its Implication as a Therapeutic Target for Prostate Cancer Cancer Res., May 15, 2007; 67(10): 4904 - 4914. [Abstract] [Full Text] [PDF]

				C. Glidewell-Kenney, L. A. Hurley, L. Pfaff, J. Weiss, J. E. Levine, and J. L. Jameson Nonclassical estrogen receptor {alpha} signaling mediates negative feedback in the female mouse reproductive axis PNAS, May 8, 2007; 104(19): 8173 - 8177. [Abstract] [Full Text] [PDF]

				J. L. Kipp, S. M. Kilen, S. Bristol-Gould, T. K. Woodruff, and K. E. Mayo Neonatal Exposure to Estrogens Suppresses Activin Expression and Signaling in the Mouse Ovary Endocrinology, May 1, 2007; 148(5): 1968 - 1976. [Abstract] [Full Text] [PDF]

				C. Wang and S. K. Roy Development of Primordial Follicles in the Hamster: Role of Estradiol-17{beta} Endocrinology, April 1, 2007; 148(4): 1707 - 1716. [Abstract] [Full Text] [PDF]