Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly

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				J. G. Harb, B. I. Chyla, and C. S. Huettner Loss of Bcl-x in Ph+ B-ALL increases cellular proliferation and does not inhibit leukemogenesis Blood, April 1, 2008; 111(7): 3760 - 3769. [Abstract] [Full Text] [PDF]

				R. L. Schweers, J. Zhang, M. S. Randall, M. R. Loyd, W. Li, F. C. Dorsey, M. Kundu, J. T. Opferman, J. L. Cleveland, J. L. Miller, et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation PNAS, December 4, 2007; 104(49): 19500 - 19505. [Abstract] [Full Text] [PDF]

				A. Diwan, A. G. Koesters, A. M. Odley, S. Pushkaran, C. P. Baines, B. T. Spike, D. Daria, A. G. Jegga, H. Geiger, B. J. Aronow, et al. Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis PNAS, April 17, 2007; 104(16): 6794 - 6799. [Abstract] [Full Text] [PDF]

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				L. Garcon, C. Rivat, C. James, C. Lacout, V. Camara-Clayette, V. Ugo, Y. Lecluse, A. Bennaceur-Griscelli, and W. Vainchenker Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells Blood, September 1, 2006; 108(5): 1551 - 1554. [Abstract] [Full Text] [PDF]

				P. F. Vitiello, R. J. Staversky, S. C. Gehen, C. J. Johnston, J. N. Finkelstein, T. W. Wright, and M. A. O'Reilly p21Cip1 Protection against Hyperoxia Requires Bcl-XL and Is Uncoupled from Its Ability to Suppress Growth Am. J. Pathol., June 1, 2006; 168(6): 1838 - 1847. [Abstract] [Full Text] [PDF]

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				M. M. Rhodes, P. Kopsombut, M. C. Bondurant, J. O. Price, and M. J. Koury Bcl-xL prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin Blood, September 1, 2005; 106(5): 1857 - 1863. [Abstract] [Full Text] [PDF]

				J. M. Savitt, S. S. Jang, W. Mu, V. L. Dawson, and T. M. Dawson Bcl-x Is Required for Proper Development of the Mouse Substantia Nigra J. Neurosci., July 20, 2005; 25(29): 6721 - 6728. [Abstract] [Full Text] [PDF]

				W. Tong, J. Zhang, and H. F. Lodish Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways Blood, June 15, 2005; 105(12): 4604 - 4612. [Abstract] [Full Text] [PDF]

				N. Zhang and Y.-W. He The Antiapoptotic Protein Bcl-xL Is Dispensable for the Development of Effector and Memory T Lymphocytes J. Immunol., June 1, 2005; 174(11): 6967 - 6973. [Abstract] [Full Text] [PDF]

				M. J. Koury, S. T. Koury, P. Kopsombut, and M. C. Bondurant In vitro maturation of nascent reticulocytes to erythrocytes Blood, March 1, 2005; 105(5): 2168 - 2174. [Abstract] [Full Text] [PDF]

				K. W. Harder, C. Quilici, E. Naik, M. Inglese, N. Kountouri, A. Turner, K. Zlatic, D. M. Tarlinton, and M. L. Hibbs Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1 Blood, December 15, 2004; 104(13): 3901 - 3910. [Abstract] [Full Text] [PDF]

				H. Hon, E. B. Rucker III, L. Hennighausen, and J. Jacob bcl-xL Is Critical for Dendritic Cell Survival In Vivo J. Immunol., October 1, 2004; 173(7): 4425 - 4432. [Abstract] [Full Text] [PDF]

				U. Klingmuller Turning terminal differentiation into proliferative responses Blood, December 15, 2003; 102(13): 4252 - 4253. [Full Text] [PDF]

				I. Lebigot, P. Gardellin, L. Lefebvre, H. Beug, J. Ghysdael, and C. T. Quang Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling Blood, December 15, 2003; 102(13): 4555 - 4562. [Abstract] [Full Text] [PDF]

				M. J. Weiss New Insights Into Erythropoietin and Epoetin Alfa: Mechanisms of Action, Target Tissues, and Clinical Applications Oncologist, December 1, 2003; 8(90003): 18 - 29. [Abstract] [Full Text] [PDF]

				K. Li, M. P. Menon, V. G. Karur, S. Hegde, and D. M. Wojchowski Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells Blood, November 1, 2003; 102(9): 3147 - 3153. [Abstract] [Full Text] [PDF]

				L. Haughn, R. G. Hawley, D. K. Morrison, H. von Boehmer, and D. M. Hockenbery BCL-2 and BCL-XL Restrict Lineage Choice during Hematopoietic Differentiation J. Biol. Chem., June 27, 2003; 278(27): 25158 - 25165. [Abstract] [Full Text] [PDF]

				K. Hafid-Medheb, Y. Augery-Bourget, M.-N. Minatchy, N. Hanania, and J. Robert-Lezenes Bcl-XL is required for heme synthesis during the chemical induction of erythroid differentiation of murine erythroleukemia cells independently of its antiapoptotic function Blood, April 1, 2003; 101(7): 2575 - 2583. [Abstract] [Full Text] [PDF]

				C. Tian, P. Gregoli, and M. Bondurant The function of the bcl-x promoter in erythroid progenitor cells Blood, March 15, 2003; 101(6): 2235 - 2242. [Abstract] [Full Text] [PDF]

				M. Walsh, R. J. Lutz, T. G. Cotter, and R. O'Connor Erythrocyte survival is promoted by plasma and suppressed by a Bak-derived BH3 peptide that interacts with membrane-associated Bcl-XL Blood, May 1, 2002; 99(9): 3439 - 3448. [Abstract] [Full Text] [PDF]

				G. Riedlinger, R. Okagaki, K.-U. Wagner, E. B. Rucker III, T. Oka, K. Miyoshi, J. A. Flaws, and L. Hennighausen Bcl-x Is Not Required for Maintenance of Follicles and Corpus Luteum in the Postnatal Mouse Ovary Biol Reprod, February 1, 2002; 66(2): 438 - 444. [Abstract] [Full Text] [PDF]