spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gaufo, G. O.
Right arrow Articles by Capecchi, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gaufo, G. O.
Right arrow Articles by Capecchi, M. R.
Altman, J. and Bayer, S. A (1980). Development of the brain stem in the rat. 11. Thymidine-radiographic study of the time of origin of neurons of the upper medulla, excluding the vestibular and auditory nuclei. J. Comp. Neurol 194, 37-56.[Medline]

Barrow, J. R. and Capecchi, M. R (1996). Targeted disruption of the hoxb-2 locus in mice interferes with expression of hoxb-1 and hoxb-4. Development 122, 3817-3828.[Abstract]

Bell, E., Wingate, R. J. and Lumsden, A (1999). Homeotic transformation of rhombomere identity after localized Hoxb1 expression. Science 284, 2168-2171.[Abstract/Free Full Text]

Briscoe, J., Pierani, A., Jessell, T. M. and Ericson, J (2000). A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101, 435-445.[Medline]

Briscoe, J., Sussel, L., Serup, P., Hartigan-O'Connor, D., Jessell, T. M., Rubenstein, J. L. and Ericson, J (1999). Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398, 622-627.[Medline]

Carpenter, E. M., Goddard, J. M., Chisaka, O., Manley, N. R. and Capecchi, M. R (1993). Loss of Hox-A1 ( Hox-1.6 ) function results in the reorganization of the murine hindbrain. Development 118, 1063-1075.[Abstract]

Chiang, C., Litingtung, Y., Lee, E., Young, K.E. Corden, J.L., Westphal, H. and Beachy, P.A (1996). Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.[Medline]

Davenne, M., Maconochie, M. K., Neun, R., Pattyn, A., Chambon, P., Krumlauf, R. and Rijli, F. M (1999). Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron 22, 677-691.[Medline]

Dolle, P., Izpis\234a-Belmonte, J.-C., Falkenstein, H., Renucci, A. and Duboule, D (1989). Coordinate expression of the murine Hox-5 complex homeobox-containing genes during limb pattern formation. Nature 342, 767-772.[Medline]

Duboule, D (1998). Vertebrate hox gene regulation: clustering and/or colinearity?. Curr. Opin. Genet. Dev 8, 514-518.[Medline]

Edlund, T. and Jessell, T. M (1999). Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system. Cell 96, 211-224.[Medline]

Ericson, J., Morton, S., Kawakami, A., Roelink, H. and Jessell, T. M (1996). Two critical periods of sonic hedgehog signaling required for specification of motor neuron identity. Cell 87, 661-673.[Medline]

Ericson, J., Rashbass, P., Schedl, A., Brenner-Morton, S., Kawakami, A., van Heynigen, V. and Jessell, T. M (1997). Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90, 169-189.[Medline]

Flanagan, J. G. and Vanderhaeghen, P (1998). The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci 21, 309-345.[Medline]

Fode, C., Gradwohl, G., Morin, X., Dierich, A., LeMur, M., Goridis, C. and Guillemot, F (1998). The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron 20, 483-494.[Medline]

Frohman, M. A., Boyle, M. and Martin, G. R (1990). Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110, 589-607.[Abstract/Free Full Text]

Goddard, J. M., Rossel, M., Manley, N. R. and Capecchi, M. R (1996). Mice with targeted disruption of Hoxb1 fail to form the motor nucleus of the VIIth nerve. Development 122, 3217-3228.[Abstract]

Godwin, A. R., Stadler, H. S., Nakamura, K. and Capecchi, M. R (1998). Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proc. Natl. Acad. Sci. USA 95, 13042-13047.[Abstract/Free Full Text]

Gradwohl, G., Fode, C. and Guillemot, F (1996). Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev. Biol 180, 227-241.[Medline]

Graham, A., Papalopulu, N. and Krumlauf, R (1989). The murine and Drosophila homeobox gene complexes have common features of organization and expression. Cell 57, 367-378.[Medline]

Guillemot, F., Lo., L., Johnson, J. E., Auerbach, A., Anderson, D. J. and Joyner, A. L (1993). Mammalian achaete-scute homolog 1is required for early development of olfactory and autonomic neurons. Cell 75, 463-476.[Medline]

Heitzler, P., Bourouis, M., Ruel, L., Carteret, C. and Simpson, P (1996). Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122, 161-171.[Abstract]

Hirsch, M., Tiveron, M., Buillemot, F., Brunet, J. and Goridis, C (1998). Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development 125, 599-608.[Abstract]

Jan, Y. N. and Jan, L. Y (1994). Genetic control of cell fate specification in Drosophila peripheral nervous system. Annu. Rev. Genet 28, 373-393.[Medline]

Johnson, J. E., Birren, S. J. and Anderson, D. J (1990). Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors. Nature 346, 858-861.[Medline]

Jungbluth, S., Bell, E. and Lumsden, A (1999). Specification of distinct motor neuron identities by the singular activities of individual Hox genes. Development 126, 2751-2758.[Abstract]

Kageyama, R. and Nakanishi, S (1997). Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr. Opin. Genet. Dev 7, 659-665.[Medline]

Krumlauf, R (1994). Hox genes in vertebrate development. Cell 78, 191-201.[Medline]

Lee, J. E (1997). Basic helix-loop-helix genes in neural development. Curr. Opin. Neurobiol 7, 13-20.[Medline]

Lumsden, A. and Keynes, R (1989). Segmental patterns of neuronal development in the chick hindbrain. Nature 337, 424-428.[Medline]

Lumsden, A (1990). The cellular basis of segmentation in the developing hindbrain. Trends Neurosci 13, 329-335.[Medline]

Lumsden, A. and Krumlauf, R (1996). Patterning the vertebrate neuraxis. Science 274, 1109-1115.[Abstract/Free Full Text]

Ma, Q., Kintner, C. and Anderson, D.J (1996). Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87, 43-52.[Medline]

Ma, Q., Chen, Z., del Barco Barrantes, I., de la Pompa, J. L. and Anderson., D. J (1998). neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia. Neuron 20, 469-482.[Medline]

Ma, Q., Fode, C., Guillemot, F. and Anderson, D. J (1999). Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root ganglia. Genes Dev 13, 1717-1728.[Abstract/Free Full Text]

Ma, Q., Sommer, L., Cserjesi, P. and Anderson, D. J (1997). Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands. J. Neurosci 17, 3644-3652.[Abstract/Free Full Text]

Manley, N. R. and Capecchi, M. R (1995). The role of hoxa-3 in mouse thymus and thyroid development. Development 121, 1989-2003.[Abstract]

Mansour, S. J., Thomas, K. R. and Capecchi, M. R (1988). Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 336, 348-352.[Medline]

Marin, F. and Puelles, L (1995). Morphological fate of rhombomeres in quail/chick chimeras: a segmental analysis of hindbrain nuclei. Eur. J. Neurosci 7, 1714-1738.[Medline]

Mark, M., Lufkin, T., Vonesch, J.-L., Ruberte, E., Olivo, J.-C., Dolle, P., Gorry, P., Lumsden, A. and Chambon, P (1993). Two rhombomeres are altered in Hoxa-1 mutant mice. Development 119, 319-338.[Abstract]

McConnell, S. K (1995). Constructing the cerebral cortex: neurogenesis and fate determination. Neuron 15, 761-768.[Medline]

Murphy, P., Davidson, D. R. and Hill, R. E (1989). Segment-specific expression of a homeobox-containing gene in the mouse hindbrain. Nature 341, 156-159.[Medline]

Murphy, P. and Hill, R. E (1991). Expression of the mouse labial-like homeobox-containing genes, Hox 2.9 and Hox 1.6 , during segmentation of the hindbrain. Development 111, 61-74.[Abstract]

Nagy, A., Rossant, J., Abramow-Newerly, W. and Roder, J. C (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.[Abstract/Free Full Text]

Olson, E. N., Arnold, H.-H., Rigby, P. W. J. and Wold, B. J (1996). Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 85, 1-4.[Medline]

Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D (1997). Fringe modulates Notch-ligand interactions. Nature 387, 908-912.[Medline]

Pata, I., Studer, M., van Doorninck, J. H., Briscoe, J., Kuuse, S., Engel, J. D., Grosveld, F. and Karis, A (2000). The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development 126, 5523-5531.[Abstract]

Pattyn, A., Hirsch, M., Goridis, C. and Brunet, J. F (2000). Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development 127, 1349-1358.[Abstract]

Pattyn, A., Morin, X., Cremer, H., Goridis, C. and Brunet, J (1997). Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development 124, 4065-4075.[Abstract]

Pfaff, S. L., Mendelsohn, M., Stewart, C.L., Edlund, T. and Jessell, T.M (1996). Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell 84, 309-320.[Medline]

Pierani, A., Brenner-Morton, S., C., C. and Jessell, T. M (1999). A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell 97, 903-915.[Medline]

P\232pperl, H., Bienz, M., Studer, M., Chan, S., Aparicio, S., Brenner, S., Mann, R. S. and Krumlauf, R (1995). Segmented expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81, 1031-1042.[Medline]

Rossel, M. and Capecchi, M. R (1999). Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development 126, 5027-5040.[Abstract]

Ruiz i Altaba, A., Prezioso, V. R., Darnell, J. E. and Jessell, T. M (1993). Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate. Mech. Dev 44, 91-108.[Medline]

Sasai, Y (1998). Identifying the missing link: genes that connect neural induction and primary neurogenesis in vertebrate embryos. Neuron 21, 455-458.[Medline]

Schwenk, F., Baron, U. and Rajewsky, K (1995). A cre- transgenic mouse strain for the ubiquitous deletion of loxP- flanked gene segments including deletion in germ cells. Nucleic Acids Res 23, 5080-5081.[Free Full Text]

Sockanathan, S. and Jessell, T. M (1998). Motor neuron-derived retinoid signaling specifies the subtype identity of spinal motor neurons. Cell 94, 503-514.[Medline]

Studer, M., Lumsden, A., Ariza-McNaughton, L., Bradley, A. and Krumlauf, R (1996). Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb1. Nature 384, 630-634.[Medline]

Taber Pierce, E (1973). Time of origin of neurons in the brain stem of the mouse. Prog. Brain Res 40, 53-65.[Medline]

Tanabe, Y. and Jessell, T. M (1996). Diversity and pattern in the developing spinal cord. Science 274, 1115-1123.[Abstract/Free Full Text]

Tsuchida, T., Ensini, M., Morton, S. B., Baldassare, M., Edlund, T., Jessell, T. M. and Pfaff, S. L (1995). Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957-970.

Wei, Y., Yu, L., Bowen, J., Gorovsky, M. A. and Allis, C. D (1999). Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell 97, 99-109.[Medline]

Weinstein, D. C., Ruiz i Altaba, A., Chen, W. S., P., H., Prezioso, V. R., Jessell, T. M. and Darnell, J. E. J (1994). The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell 78, 575-588.[Medline]




This article has been cited by other articles:


Home page
DevelopmentHome page
M. A. Wassef, D. Chomette, M. Pouilhe, A. Stedman, E. Havis, C. Desmarquet-Trin Dinh, S. Schneider-Maunoury, P. Gilardi-Hebenstreit, P. Charnay, and J. Ghislain
Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors
Development, October 15, 2008; 135(20): 3369 - 3378.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
M. Gouti and A. Gavalas
Hoxb1 Controls Cell Fate Specification and Proliferative Capacity of Neural Stem and Progenitor Cells
Stem Cells, August 1, 2008; 26(8): 1985 - 1997.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. P. Coutinho, C. Borday, J. Gilthorpe, S. Jungbluth, J. Champagnat, A. Lumsden, and G. Fortin
Induction of a Parafacial Rhythm Generator by Rhombomere 3 in the Chick Embryo
J. Neurosci., October 20, 2004; 24(42): 9383 - 9390.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
O. A. Samad, M. J. Geisen, G. Caronia, I. Varlet, V. Zappavigna, J. Ericson, C. Goridis, and F. M. Rijli
Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins
Development, August 15, 2004; 131(16): 4071 - 4083.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
J. Briscoe and D. G. Wilkinson
Establishing neuronal circuitry: Hox genes make the connection
Genes & Dev., July 15, 2004; 18(14): 1643 - 1648.
[Full Text] [PDF]


Home page
Genes Dev.Home page
B. R. Arenkiel, P. Tvrdik, G. O. Gaufo, and M. R. Capecchi
Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry
Genes & Dev., July 1, 2004; 18(13): 1539 - 1552.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
G. O. Gaufo, S. Wu, and M. R. Capecchi
Contribution of Hox genes to the diversity of the hindbrain sensory system
Development, March 15, 2004; 131(6): 1259 - 1266.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
Y. Murakami, M. Pasqualetti, Y. Takio, S. Hirano, F. M. Rijli, and S. Kuratani
Segmental development of reticulospinal and branchiomotor neurons in lamprey: insights into the evolution of the vertebrate hindbrain
Development, March 1, 2004; 131(5): 983 - 995.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. C. Williams Jr., M. Cai, and G. M. Clore
Molecular Basis for Synergistic Transcriptional Activation by Oct1 and Sox2 Revealed from the Solution Structure of the 42-kDa Oct1{middle dot}Sox2{middle dot}Hoxb1-DNA Ternary Transcription Factor Complex
J. Biol. Chem., January 9, 2004; 279(2): 1449 - 1457.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
A. Gavalas, C. Ruhrberg, J. Livet, C. E. Henderson, and R. Krumlauf
Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes
Development, December 1, 2003; 130(23): 5663 - 5679.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
G. O. Gaufo, K. R. Thomas, and M. R. Capecchi
Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons
Development, November 1, 2003; 130(21): 5191 - 5201.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
A. Pattyn, A. Vallstedt, J. M. Dias, O. A. Samad, R. Krumlauf, F. M. Rijli, J.-F. Brunet, and J. Ericson
Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors
Genes & Dev., March 15, 2003; 17(6): 729 - 737.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
J. M. McClintock, M. A. Kheirbek, and V. E. Prince
Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention
Development, March 7, 2003; 129(10): 2339 - 2354.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
T. Theil, L. Ariza-McNaughton, M. Manzanares, J. Brodie, R. Krumlauf, and D. G. Wilkinson
Requirement for downregulation of kreisler during late patterning of the hindbrain
Development, March 5, 2003; 129(6): 1477 - 1485.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. Studer
Initiation of facial motoneurone migration is dependent on rhombomeres 5 and 6
Development, October 1, 2001; 128(19): 3707 - 3716.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gaufo, G. O.
Right arrow Articles by Capecchi, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gaufo, G. O.
Right arrow Articles by Capecchi, M. R.