Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state

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				J. Dai and A.B.M. Rabie VEGF: an Essential Mediator of Both Angiogenesis and Endochondral Ossification J. Dent. Res., October 1, 2007; 86(10): 937 - 950. [Abstract] [Full Text] [PDF]

				A. N. Athanasopoulos, D. Schneider, T. Keiper, V. Alt, U. R. Pendurthi, U. M. Liegibel, U. Sommer, P. P. Nawroth, C. Kasperk, and T. Chavakis Vascular Endothelial Growth Factor (VEGF)-induced Up-regulation of CCN1 in Osteoblasts Mediates Proangiogenic Activities in Endothelial Cells and Promotes Fracture Healing J. Biol. Chem., September 14, 2007; 282(37): 26746 - 26753. [Abstract] [Full Text] [PDF]

				S. H. L. George, M. Gertsenstein, K. Vintersten, E. Korets-Smith, J. Murphy, M. E. Stevens, J. J. Haigh, and A. Nagy Developmental and adult phenotyping directly from mutant embryonic stem cells PNAS, March 13, 2007; 104(11): 4455 - 4460. [Abstract] [Full Text] [PDF]

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				E. Zelzer, R. Mamluk, N. Ferrara, R. S. Johnson, E. Schipani, and B. R. Olsen VEGFA is necessary for chondrocyte survival during bone development Development, May 1, 2004; 131(9): 2161 - 2171. [Abstract] [Full Text] [PDF]

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				B. C. J. van der Eerden, M. Karperien, and J. M. Wit Systemic and Local Regulation of the Growth Plate Endocr. Rev., December 1, 2003; 24(6): 782 - 801. [Abstract] [Full Text] [PDF]

				A. J. Pantuck, G. Zeng, A. S. Belldegrun, and R. A. Figlin Pathobiology, Prognosis, and Targeted Therapy for Renal Cell Carcinoma: Exploiting the Hypoxia-Induced Pathway Clin. Cancer Res., October 15, 2003; 9(13): 4641 - 4652. [Abstract] [Full Text] [PDF]

				J. C. Yang, L. Haworth, R. M. Sherry, P. Hwu, D. J. Schwartzentruber, S. L. Topalian, S. M. Steinberg, H. X. Chen, and S. A. Rosenberg A Randomized Trial of Bevacizumab, an Anti-Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer N. Engl. J. Med., July 31, 2003; 349(5): 427 - 434. [Abstract] [Full Text] [PDF]

				S. Ivkovic, B. S. Yoon, S. N. Popoff, F. F. Safadi, D. E. Libuda, R. C. Stephenson, A. Daluiski, and K. M. Lyons Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development Development, June 15, 2003; 130(12): 2779 - 2791. [Abstract] [Full Text] [PDF]

				M. Hirashima, M. Ogawa, S. Nishikawa, K. Matsumura, K. Kawasaki, M. Shibuya, and S.-I. Nishikawa A chemically defined culture of VEGFR2+ cells derived from embryonic stem cells reveals the role of VEGFR1 in tuning the threshold for VEGF in developing endothelial cells Blood, March 15, 2003; 101(6): 2261 - 2267. [Abstract] [Full Text] [PDF]

				E. Zelzer, W. McLean, Y.-S. Ng, N. Fukai, A. M. Reginato, S. Lovejoy, P. A. D'Amore, and B. R. Olsen Skeletal defects in VEGF120/120 mice reveal multiple roles for VEGF in skeletogenesis Development, March 6, 2003; 129(8): 1893 - 1904. [Abstract] [Full Text] [PDF]

				S. Childs, J.-N. Chen, D. M. Garrity, and M. C. Fishman Patterning of angiogenesis in the zebrafish embryo Development, March 4, 2003; 129(4): 973 - 982. [Abstract] [Full Text] [PDF]

				Y. Nakamichi, C. Shukunami, T. Yamada, K.-i. Aihara, H. Kawano, T. Sato, Y. Nishizaki, Y. Yamamoto, M. Shindo, K. Yoshimura, et al. Chondromodulin I Is a Bone Remodeling Factor Mol. Cell. Biol., January 15, 2003; 23(2): 636 - 644. [Abstract] [Full Text] [PDF]

				D. L. Brutsaert Cardiac Endothelial-Myocardial Signaling: Its Role in Cardiac Growth, Contractile Performance, and Rhythmicity Physiol Rev, January 1, 2003; 83(1): 59 - 115. [Abstract] [Full Text] [PDF]

				A. Behrens, J. Haigh, F. Mechta-Grigoriou, A. Nagy, M. Yaniv, and E. F. Wagner Impaired intervertebral disc formation in the absence of Jun Development, January 1, 2003; 130(1): 103 - 109. [Abstract] [Full Text] [PDF]

				N. Cheng, D. M. Brantley, H. Liu, Q. Lin, M. Enriquez, N. Gale, G. Yancopoulos, D. P. Cerretti, T. O. Daniel, and J. Chen Blockade of EphA Receptor Tyrosine Kinase Activation Inhibits Vascular Endothelial Cell Growth Factor-Induced Angiogenesis Mol. Cancer Res., November 1, 2002; 1(1): 2 - 11. [Abstract] [Full Text] [PDF]

				S. R. Wedge, D. J. Ogilvie, M. Dukes, J. Kendrew, R. Chester, J. A. Jackson, S. J. Boffey, P. J. Valentine, J. O. Curwen, H. L. Musgrove, et al. ZD6474 Inhibits Vascular Endothelial Growth Factor Signaling, Angiogenesis, and Tumor Growth following Oral Administration Cancer Res., August 15, 2002; 62(16): 4645 - 4655. [Abstract] [Full Text] [PDF]

				E. Tham, J. Wang, F. Piehl, and G. Weber Upregulation of VEGF-A Without Angiogenesis in a Mouse Model of Dilated Cardiomyopathy Caused by Mitochondrial Dysfunction J. Histochem. Cytochem., July 1, 2002; 50(7): 935 - 944. [Abstract] [Full Text] [PDF]

				E. Schipani, H. E. Ryan, S. Didrickson, T. Kobayashi, M. Knight, and R. S. Johnson Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival Genes & Dev., November 1, 2001; 15(21): 2865 - 2876. [Abstract] [Full Text] [PDF]

				N. Ferrara Role of vascular endothelial growth factor in regulation of physiological angiogenesis Am J Physiol Cell Physiol, June 1, 2001; 280(6): C1358 - C1366. [Abstract] [Full Text] [PDF]

				D. S. Sohal, M. Nghiem, M. A. Crackower, S. A. Witt, T. R. Kimball, K. M. Tymitz, J. M. Penninger, and J. D. Molkentin Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein Circ. Res., July 6, 2001; 89(1): 20 - 25. [Abstract] [Full Text] [PDF]