Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon

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Anderson, S. A., Eisenstat, D. D., Shi, L. and Rubenstein, J. L. R (1997). Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278, 474-476.[Abstract/Free Full Text]

Anderson, S. A., Qiu, M., Bulfone, A., Eisenstat, D. D., Meneses, J., Pedersen, R. and Rubenstein, J.L.R (1997). Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons. Neuron 19, 27-37.[Medline]

Anderson, S., Mione, M., Yun, K. and Rubenstein, J. L.R (1999). Differential origins of neocortical projection and local circuit neurons: role of Dlx genes in neocortical interneuronogenesis. Cereb. Cortex 9, 646-654.[Abstract/Free Full Text]

Bishop, K. M., Goudreau, G., O'Leary, D.D (2000). Regulation of area identity in the mammalian neocortex by Emx2 and Pax6. Science 288, 344-349.[Abstract/Free Full Text]

Briscoe, J., Sussel, L., Serup, P., Hartigan-O'Connor, D., Jessell, T. M.,Rubenstein, J. L. R. and Ericson, J (1999). Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398, 622-627.[Medline]

Briscoe, J., Pierani, A., Jessell, T. M. and Ericson, J (2000). A homeodomain protein code specifies progenitor cell identity and neural fate in the ventral neural tube. Cell 101, 435-445.[Medline]

Bulfone, A. Kim, H.-J., Puelles, L., Porteus, M. H., Grippo, J. F. and Rubenstein, J. L. R (1993). The mouse Dlx-2 ( Tes-1 ) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech. Dev 40, 129-140.[Medline]

Bulfone, A., Wang, F., Hevner, R., Anderson, S., Cutforth, T., Chen, S. Meneses, J., Pedersen, R., Axel, R. and Rubenstein, J. L. R (1998). An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. Neuron 21, 1273-1282.[Medline]

Bulfone, A., Martinez, S., Marigo, V., Campanella, M., Basile, A., Quaderi, N., Gattuso, C., Rubenstein, J. L. and Ballabio, A (1999). Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development. Mech. Dev 84, 133-138.[Medline]

Caric, D., Gooday, D., Hill, R. E., McConnell, S. K. and Price, D. J (1997). Determination of the migratory capacity of embryonic cortical cells lacking the transcription factor Pax-6. Development 124, 5087-5096.[Abstract]

Casarosa, S., Fode, C. and Guillemot, F (1999). Mash1 regulates neurogenesis in the ventral telencephalon. Development 126, 525-534.[Abstract]

Chapouton, P., G\212rtner, A. and G\232tz, M (1999). The role of Pax6 in restricting cell migration between developing cortex and basal ganglia. Development 126, 5569-5579.[Abstract]

Chiang, C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H. and Beachy, P. A (1996). Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.[Medline]

Eisenstat, D. D., Liu, J. K., Mione, M., Zhong, W., Yu, G., Anderson, S., Ghatas, I., Puelles, L. and Rubenstein, J. L. R (1999). DLX-1, DLX-2, and DLX-5 expression define distinct dtages of basal forebrain differentiation. J. Comp. Neurol 414, 217-237.[Medline]

Ericson, J., Briscoe, J., Rashbass, P., van Heyningen, V. and Jessell, T. M (1997). Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube. Cold Spring Harb. Symp. Quant. Biol 62, 451-466.[Medline]

Ericson, J., Rashbass, P., Schedl, A., Brenner-Morton, S., Kawakami, A., van Heyningen, V., Jessell, T. M. and Briscoe, J (1997). Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90, 169-180.[Medline]

Fishell, G., Mason, C.A., Hatten, M.E (1993). Dispersion of neural progenitors within the germinal zones of the forebrain. Nature 362, 636-638.[Medline]

Fode, C., Ma, Q., Casarosa, S., Ang, S. L., Anderson, D. J., and Guillemot, F (2000). A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev 14, 67-80.[Abstract/Free Full Text]

Galceran, J., Miyashita-Lin, E. M., Devaney, E., Rubenstein, J. L. R. and Grosschedl, R (2000). Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development 127, 469-482.[Abstract]

Goldman, S. A. and Luskin, M. B (1998). Strategies utilized by migrating neurons of the postnatal vertebrate forebrain. Trends Neurosci 21, 107-114.[Medline]

G\232tz, M., Stoykova, A. and Gruss, P. ( (1998). Pax6 controls radial glia differentiation in the cerebral cortex. Neuron 21, 1031-1044.[Medline]

Grindley, J. C., Hargett, L. K., Hill, R. E., Ross, A. and Hogan, B. L (1997). Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon. Mech. Dev 64, 111-126.[Medline]

Hill, R. E, Favor, J., Hogan, B. L., Ton, C. C., Saunders, G. F., Hanson, I. M., Prosser, J., Jordan, T., Hastie, N.D. and van Heyningen, V (1991). Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature 354, 522-525.[Medline]

Horton, S., Meredith, A., Richarson, J. A. and Johnson, J. E (1999). Correct coordination of neuronal differentiation events in ventral forebrain requires the bHLH factor MASH1. Mol. Cell. Neurosci 14, 355-369.[Medline]

Hsieh-Li, H. M., Witte, D. P., Szucsik, J. C., Weinstein, M., Li, H. and Potter, S. S (1995). Gsh-2, a murine homeobox gene expressed in the developing brain. Mech. Dev 50, 177-186.[Medline]

Lavdas, A. A., Grigoriou, M., Pachnis, V. and Parnavelas, J. G (1999). The medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex. J. Neurosci 99, 7881-7888.

Lee, K. J. and Jessell, T. M (1999). The specification of dorsal cell fates in the vertebrate central nervous system. Annu. Rev. Neurosci 22, 261-294.[Medline]

Lee, S. M., Tole, S., Grove, E., McMahon, A. P (2000). A local Wnt-3a signal is required for development of the mammalian hippocampus. Development 127, 457-467.[Abstract]

Li, H., Zeitler, P. S., Valerius, M. T., Small, K. and Potter, S. S (1996). Gsh-1, an orphan Hox gene, is required for normal pituitary development. EMBO J 15, 714-724.[Medline]

Lu, S., Bogarad, L. D., Murtha, M. T., Ruddle, F. H (1992). Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord. Proc. Natl. Acad. Sci. USA 89, 8053-8057.[Abstract/Free Full Text]

Mar\222n, O., Anderson, S. A. and Rubenstein, J. L. R (2000). Origin and molecular specification of striatal interneurons,. J. Neurosci 20, 6063-6076.[Abstract/Free Full Text]

Mastick, G. S., Davis, N. M., Andrew, G. L. and Easter, S. S., Jr (1997). Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain. Development 124, 1985-1997.[Abstract]

Oliver, G., Mailhos, A., Wehr, R., Copeland, N. G., Jenkins, N. A. and Gruss, P (1995). Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121, 4045-4055.[Abstract]

Osumi, N., Hirota, A., Ohuchi, H., Nakafuku, M., Iimura, T., Kuratani, S., Fujiwara, M., Noji, S., Eto, K (1997). Pax-6 is involved in the specification of hindbrain motor neuron subtype. Development 124, 2961-2967.[Abstract]

Pierani, A., Brenner-Morton, S., Chiang, C., Jessell, T. M (1999). A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell 97, 903-915.[Medline]

Porter, F. D., Drago, J., Xu, Y., Cheema, S. S., Wassif, C., Huang, S. P., Lee, E., Grinberg, A., Massalas, J. S., Bodine, D., Alt, F., Westphal, H (1997). Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development. Development 124, 2935-2944.[Abstract]

Porteus, M. H., Bulfone, A., Liu, J. K., Puelles, L., Lo, L. C. and Rubenstein, J. L. R (1994). DLX-2, MASH-1, MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. J. Neurosci 14, 6370-6383.[Abstract]

Puelles, L., Kuwana, E., Puelles, E., Bulfone, A., Shimamura, K., Keleher, J., Smiga, S. and Rubenstein, J. L. R (2000). Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the genes Dlx-2, Emx-1, Nkx-2.1, Pax-6 and Tbr-1. J. Comp. Neurol 424, 409-438.[Medline]

Qiu, M., Bulfone, A., Martinez, S., Meneses, J. J., Shimamura, K., Pedersen, R. A. and Rubenstein, J. L. R (1995). Role of Dlx-2 in head development and evolution: null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain. Genes Dev 9, 2523-2538.[Abstract/Free Full Text]

Qiu, M., Shimamura, K., Sussel, L., Chen, S. and Rubenstein, J. L. R (1998). Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech. Dev 72, 77-88.[Medline]

Sander, M., Paydar, S., Ericson, J., Briscoe, J., Berber, E. German, M., Jessell., T. and Rubenstein, J. L. R (2000). Ventral neural patterning by Nkx homeobox genes: Nkx6.1 control somatic motor neuron and ventral interneuron fates. Genes Dev 14, 2134-2139.[Abstract/Free Full Text]

Sheth, A. N. and Bhide, P. G (1997). Concurrent cellular output from two proliferative populations in the early embryonic mouse corpus striatum. J. Comp. Neurol 383, 220-230.[Medline]

Shoji, H., Ito, T., Wakamatsu, Y., Hayasaka, N., Ohsaki, K., Oyanagi, M., Kominami, R., Kondoh, H., Takahashi, N (1996). Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech. Dev 56, 25-39.[Medline]

Smith-Fern\207ndez, A., Pieau, C., Reperant, J., Boncinelli, E. and Wassef, M (1998). Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtleand frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Development 125, 2099-2111.[Abstract]

Solloway, M. J. and Robertson, E. J (1999). Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126, 1753-1768.[Abstract]

Stoykova, A., Fritsch, R., Walther, C. and Gruss, P (1996). Forebrain patterning defects in Small eye mutant mice. Development 122, 3453-3465.[Abstract]

Stoykova, A., G\232tz, M., Gruss, P. and Price, J (1997). Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain. Development 124, 3765-3777.[Abstract]

Sussel, L., Mar\222n, O., Kimura, S. and Rubenstein, J. L. R (1999). Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126, 3359-3370.[Abstract]

Szucsik, J. C., Witte, D. P., Li, H., Pixley, S. K., Small, K. M. and Potter, S. S (1997). Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene. Dev. Biol 191, 230-242.[Medline]

Valerius, M. T., Li, H., Stock, J. L., Weinstein, M., Kaur, S., Singh, G. andPotter, S. S (1995). Gsh-1: a novel murine homeobox gene expressed in the central nervous system. Dev. Dyn 203, 337-351.[Medline]

Valverde, F., Garc\222a, C., Lopez-Mascaraque, L. and De Carlos, J. A (2000). Development of the mammillothalamic tract in normal and Pax-6 mutant mice. J. Comp. Neurol 419, 485-504.[Medline]

van der Kooy, D. and Fishell, G (1987). Neuronal birthdate underlies the development of striatal compartments. Brain Res 401, 155-161.[Medline]

Warren, N., Caric, D., Pratt, T., Clausen, J. A., Asavaritikrai, P., Mason, J. O., Hill, R. E. and Price, D. J (1999). The transcription factor, Pax6, is required for cell proliferation and differentiation in the developing cerebral cortex. Cereb. Cortex 9, 627-635.[Abstract/Free Full Text]

Warren, N. and Price, D. J. ( (1997). Roles of Pax-6 in murine diencephalic development. Development 124, 1573-1582.[Abstract]

Wawersik, S., Purcell, P., Rauchman, M., Dudley, A.T., Robertson, E.J. and Mass, R (1999). BMP7 acts in murine lens placode development. Dev. Biol 207, 176-188.[Medline]

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Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6
Development, July 1, 2003; 130(13): 2903 - 2915.
[Abstract] [Full Text] [PDF]

Z. Molnar, S. Higashi, and G. Lopez-Bendito
Choreography of Early Thalamocortical Development
Cereb Cortex, June 1, 2003; 13(6): 661 - 669.
[Abstract] [Full Text] [PDF]

S. Garel, K. J. Huffman, and J. L. R. Rubenstein
Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants
Development, May 1, 2003; 130(9): 1903 - 1914.
[Abstract] [Full Text] [PDF]

J. Stenman, R. T. Yu, R. M. Evans, and K. Campbell
Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon
Development, March 15, 2003; 130(6): 1113 - 1122.
[Abstract] [Full Text] [PDF]

K. Shinozaki, T. Miyagi, M. Yoshida, T. Miyata, M. Ogawa, S. Aizawa, and Y. Suda
Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex
Development, March 9, 2003; 129(14): 3479 - 3492.
[Abstract] [Full Text] [PDF]

M. Takahashi and N. Osumi
Pax6 regulates specification of ventral neurone subtypes in the hindbrain by establishing progenitor domains
Development, March 5, 2003; 129(6): 1327 - 1338.
[Abstract] [Full Text] [PDF]

A. Bellion, M. Wassef, and C. Metin
Early Differences in Axonal Outgrowth, Cell Migration and GABAergic Differentiation Properties between the Dorsal and Lateral Cortex
Cereb Cortex, February 1, 2003; 13(2): 203 - 214.
[Abstract] [Full Text] [PDF]

H. Wichterle, M. Alvarez-Dolado, L. Erskine, and A. Alvarez-Buylla
Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex
PNAS, January 21, 2003; 100(2): 727 - 732.
[Abstract] [Full Text] [PDF]

				A. Faedo, G. S. Tomassy, Y. Ruan, H. Teichmann, S. Krauss, S. J. Pleasure, S. Y. Tsai, M.-J. Tsai, M. Studer, and J. L. R. Rubenstein COUP-TFI Coordinates Cortical Patterning, Neurogenesis, and Laminar Fate and Modulates MAPK/ERK, AKT, and ss-Catenin Signaling Cereb Cortex, September 1, 2008; 18(9): 2117 - 2131. [Abstract] [Full Text] [PDF]

				M. C. Pinon, T. C. Tuoc, R. Ashery-Padan, Z. Molnar, and A. Stoykova Altered Molecular Regionalization and Normal Thalamocortical Connections in Cortex-Specific Pax6 Knock-Out Mice J. Neurosci., August 27, 2008; 28(35): 8724 - 8734. [Abstract] [Full Text] [PDF]

				R. S.E. Carney, L. A. Cocas, T. Hirata, K. Mansfield, and J. G. Corbin Differential Regulation of Telencephalic Pallial-Subpallial Boundary Patterning by Pax6 and Gsh2 Cereb Cortex, August 12, 2008; (2008) bhn123v1. [Abstract] [Full Text] [PDF]

				F. Garcia-Moreno, L. Lopez-Mascaraque, and J. A. de Carlos Early Telencephalic Migration Topographically Converging in the Olfactory Cortex Cereb Cortex, June 1, 2008; 18(6): 1239 - 1252. [Abstract] [Full Text] [PDF]

				A. Bithell, S. E. Finch, M. F. Hornby, and B. P. Williams Fibroblast Growth Factor 2 Maintains the Neurogenic Capacity of Embryonic Neural Progenitor Cells In Vitro but Changes Their Neuronal Subtype Specification Stem Cells, June 1, 2008; 26(6): 1565 - 1574. [Abstract] [Full Text] [PDF]

				P. P. Gopal and J. A. Golden Pax6-/- Mice Have a Cell Nonautonomous Defect in Nonradial Interneuron Migration Cereb Cortex, April 1, 2008; 18(4): 752 - 762. [Abstract] [Full Text] [PDF]

				P. Arlotta, B. J. Molyneaux, D. Jabaudon, Y. Yoshida, and J. D. Macklis Ctip2 Controls the Differentiation of Medium Spiny Neurons and the Establishment of the Cellular Architecture of the Striatum J. Neurosci., January 16, 2008; 28(3): 622 - 632. [Abstract] [Full Text] [PDF]

				M. R. Costa, N. Kessaris, W. D. Richardson, M. Gotz, and C. Hedin-Pereira The Marginal Zone/Layer I as a Novel Niche for Neurogenesis and Gliogenesis in Developing Cerebral Cortex J. Neurosci., October 17, 2007; 27(42): 11376 - 11388. [Abstract] [Full Text] [PDF]

				N. Flames, R. Pla, D. M. Gelman, J. L. R. Rubenstein, L. Puelles, and O. Marin Delineation of Multiple Subpallial Progenitor Domains by the Combinatorial Expression of Transcriptional Codes J. Neurosci., September 5, 2007; 27(36): 9682 - 9695. [Abstract] [Full Text] [PDF]

				G. Miyoshi, S. J. B. Butt, H. Takebayashi, and G. Fishell Physiologically Distinct Temporal Cohorts of Cortical Interneurons Arise from Telencephalic Olig2-Expressing Precursors J. Neurosci., July 18, 2007; 27(29): 7786 - 7798. [Abstract] [Full Text] [PDF]

				T. N. Le, G. Du, M. Fonseca, Q.-P. Zhou, J. T. Wigle, and D. D. Eisenstat Dlx Homeobox Genes Promote Cortical Interneuron Migration from the Basal Forebrain by Direct Repression of the Semaphorin Receptor Neuropilin-2 J. Biol. Chem., June 29, 2007; 282(26): 19071 - 19081. [Abstract] [Full Text] [PDF]

				M. Kohwi, M. A. Petryniak, J. E. Long, M. Ekker, K. Obata, Y. Yanagawa, J. L. R. Rubenstein, and A. Alvarez-Buylla A Subpopulation of Olfactory Bulb GABAergic Interneurons Is Derived from Emx1- and Dlx5/6-Expressing Progenitors J. Neurosci., June 27, 2007; 27(26): 6878 - 6891. [Abstract] [Full Text] [PDF]

				X. Huang, Y. Litingtung, and C. Chiang Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly Hum. Mol. Genet., June 15, 2007; 16(12): 1454 - 1468. [Abstract] [Full Text] [PDF]

				J. Berger, S. Berger, T. C. Tuoc, M. D'Amelio, F. Cecconi, J. A. Gorski, K. R. Jones, P. Gruss, and A. Stoykova Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis Development, April 1, 2007; 134(7): 1311 - 1322. [Abstract] [Full Text] [PDF]

				J. E. Long, S. Garel, M. Alvarez-Dolado, K. Yoshikawa, N. Osumi, A. Alvarez-Buylla, and J. L. R. Rubenstein Dlx-Dependent and -Independent Regulation of Olfactory Bulb Interneuron Differentiation J. Neurosci., March 21, 2007; 27(12): 3230 - 3243. [Abstract] [Full Text] [PDF]

				R. S. E. Carney, T. B. Alfonso, D. Cohen, H. Dai, S. Nery, B. Stoica, J. Slotkin, B. S. Bregman, G. Fishell, and J. G. Corbin Cell Migration along the Lateral Cortical Stream to the Developing Basal Telencephalic Limbic System. J. Neurosci., November 8, 2006; 26(45): 11562 - 11574. [Abstract] [Full Text] [PDF]

				E. Vergano-Vera, M. J. Yusta-Boyo, F. de Castro, A. Bernad, F. de Pablo, and C. Vicario-Abejon Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells Development, November 1, 2006; 133(21): 4367 - 4379. [Abstract] [Full Text] [PDF]

				E. E. Storm, S. Garel, U. Borello, J. M. Hebert, S. Martinez, S. K. McConnell, G. R. Martin, and J. L. R. Rubenstein Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers Development, May 1, 2006; 133(9): 1831 - 1844. [Abstract] [Full Text] [PDF]

				T. Nomura, J. Holmberg, J. Frisen, and N. Osumi Pax6-dependent boundary defines alignment of migrating olfactory cortex neurons via the repulsive activity of ephrin A5 Development, April 1, 2006; 133(7): 1335 - 1345. [Abstract] [Full Text] [PDF]

				M. Sur and J. L. R. Rubenstein Patterning and Plasticity of the Cerebral Cortex Science, November 4, 2005; 310(5749): 805 - 810. [Abstract] [Full Text] [PDF]

				M. Kohwi, N. Osumi, J. L. R. Rubenstein, and A. Alvarez-Buylla Pax6 Is Required for Making Specific Subpopulations of Granule and Periglomerular Neurons in the Olfactory Bulb J. Neurosci., July 27, 2005; 25(30): 6997 - 7003. [Abstract] [Full Text] [PDF]

				S. Kriks, G. M. Lanuza, R. Mizuguchi, M. Nakafuku, and M. Goulding Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord Development, July 1, 2005; 132(13): 2991 - 3002. [Abstract] [Full Text] [PDF]

				T. T. Kroll and D. D. M. O'Leary Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate PNAS, May 17, 2005; 102(20): 7374 - 7379. [Abstract] [Full Text] [PDF]

				S. Tole, R. Remedios, B. Saha, and A. Stoykova Selective Requirement of Pax6, But Not Emx2, in the Specification and Development of Several Nuclei of the Amygdaloid Complex J. Neurosci., March 9, 2005; 25(10): 2753 - 2760. [Abstract] [Full Text] [PDF]

				C. Gregg and S. Weiss CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain Development, February 1, 2005; 132(3): 565 - 578. [Abstract] [Full Text] [PDF]

				N. Haubst, J. Berger, V. Radjendirane, J. Graw, J. Favor, G. F. Saunders, A. Stoykova, and M. Gotz Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development Development, December 15, 2004; 131(24): 6131 - 6140. [Abstract] [Full Text] [PDF]

				K. Yun, A. Mantani, S. Garel, J. Rubenstein, and M. A. Israel Id4 regulates neural progenitor proliferation and differentiation in vivo Development, November 1, 2004; 131(21): 5441 - 5448. [Abstract] [Full Text] [PDF]

				M. Fuccillo, M. Rallu, A. P. McMahon, and G. Fishell Temporal requirement for hedgehog signaling in ventral telencephalic patterning Development, October 15, 2004; 131(20): 5031 - 5040. [Abstract] [Full Text] [PDF]

				N. Funatsu, T. Inoue, and S. Nakamura Gene Expression Analysis of the Late Embryonic Mouse Cerebral Cortex Using DNA Microarray: Identification of Several Region- and Layer-specific Genes Cereb Cortex, September 1, 2004; 14(9): 1031 - 1044. [Abstract] [Full Text] [PDF]

				P. Taglialatela, J. M. Soria, V. Caironi, A. Moiana, and S. Bertuzzi Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice Development, September 1, 2004; 131(17): 4239 - 4249. [Abstract] [Full Text] [PDF]