Hedgehog signaling is required for pituitary gland development

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				B. Guner, A. T. Ozacar, J. E. Thomas, and R. O. Karlstrom Graded Hedgehog and Fibroblast Growth Factor Signaling Independently Regulate Pituitary Cell Fates and Help Establish the Pars Distalis and Pars Intermedia of the Zebrafish Adenohypophysis Endocrinology, September 1, 2008; 149(9): 4435 - 4451. [Abstract] [Full Text] [PDF]

				X. Zhu, A. S. Gleiberman, and M. G. Rosenfeld Molecular Physiology of Pituitary Development: Signaling and Transcriptional Networks Physiol Rev, July 1, 2007; 87(3): 933 - 963. [Abstract] [Full Text] [PDF]

				X. Zhu, J. Zhang, J. Tollkuhn, R. Ohsawa, E. H. Bresnick, F. Guillemot, R. Kageyama, and M. G. Rosenfeld Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis Genes & Dev., October 1, 2006; 20(19): 2739 - 2753. [Abstract] [Full Text] [PDF]

				V. Hartenstein The neuroendocrine system of invertebrates: a developmental and evolutionary perspective. J. Endocrinol., September 1, 2006; 190(3): 555 - 570. [Abstract] [Full Text] [PDF]

				E. E. Storm, S. Garel, U. Borello, J. M. Hebert, S. Martinez, S. K. McConnell, G. R. Martin, and J. L. R. Rubenstein Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers Development, May 1, 2006; 133(9): 1831 - 1844. [Abstract] [Full Text] [PDF]

				H.-M. Pogoda, S. von der Hardt, W. Herzog, C. Kramer, H. Schwarz, and M. Hammerschmidt The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis Development, March 15, 2006; 133(6): 1079 - 1089. [Abstract] [Full Text] [PDF]

				V. Ribes, Z. Wang, P. Dolle, and K. Niederreither Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling Development, January 15, 2006; 133(2): 351 - 361. [Abstract] [Full Text] [PDF]

				G. Vila, M. Theodoropoulou, J. Stalla, J. C. Tonn, M. Losa, U. Renner, G. K. Stalla, and M. Paez-Pereda Expression and Function of Sonic Hedgehog Pathway Components in Pituitary Adenomas: Evidence for a Direct Role in Hormone Secretion and Cell Proliferation J. Clin. Endocrinol. Metab., December 1, 2005; 90(12): 6687 - 6694. [Abstract] [Full Text] [PDF]

				J. Chen, N. Hersmus, V. V. Duppen, P. Caesens, C. Denef, and H. Vankelecom The Adult Pituitary Contains a Cell Population Displaying Stem/Progenitor Cell and Early Embryonic Characteristics Endocrinology, September 1, 2005; 146(9): 3985 - 3998. [Abstract] [Full Text] [PDF]

				K. Grobe, M. Inatani, S. R. Pallerla, J. Castagnola, Y. Yamaguchi, and J. D. Esko Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function Development, August 15, 2005; 132(16): 3777 - 3786. [Abstract] [Full Text] [PDF]

				S. Dutta, J.-E. Dietrich, G. Aspock, R. D. Burdine, A. Schier, M. Westerfield, and Z. M. Varga pitx3 defines an equivalence domain for lens and anterior pituitary placode Development, April 1, 2005; 132(7): 1579 - 1590. [Abstract] [Full Text] [PDF]

				B. B. Madison, K. Braunstein, E. Kuizon, K. Portman, X. T. Qiao, and D. L. Gumucio Epithelial hedgehog signals pattern the intestinal crypt-villus axis Development, January 15, 2005; 132(2): 279 - 289. [Abstract] [Full Text] [PDF]

				M. De Felice and R. Di Lauro Thyroid Development and Its Disorders: Genetics and Molecular Mechanisms Endocr. Rev., October 1, 2004; 25(5): 722 - 746. [Abstract] [Full Text] [PDF]

				W. Herzog, C. Sonntag, S. von der Hardt, H. H. Roehl, Z. M. Varga, and M. Hammerschmidt Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis Development, August 1, 2004; 131(15): 3681 - 3692. [Abstract] [Full Text] [PDF]

				W. Herzog, C. Sonntag, B. Walderich, J. Odenthal, H.-M. Maischein, and M. Hammerschmidt Genetic Analysis of Adenohypophysis Formation in Zebrafish Mol. Endocrinol., May 1, 2004; 18(5): 1185 - 1195. [Abstract] [Full Text] [PDF]

				E. Roessler, Y.-Z. Du, J. L. Mullor, E. Casas, W. P. Allen, G. Gillessen-Kaesbach, E. R. Roeder, J. E. Ming, A. R. i Altaba, and M. Muenke Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features PNAS, November 11, 2003; 100(23): 13424 - 13429. [Abstract] [Full Text] [PDF]

				M. L. Brinkmeier, M. A. Potok, K. B. Cha, T. Gridley, S. Stifani, J. Meeldijk, H. Clevers, and S. A. Camper TCF and Groucho-Related Genes Influence Pituitary Growth and Development Mol. Endocrinol., November 1, 2003; 17(11): 2152 - 2161. [Abstract] [Full Text] [PDF]

				H. Kawahira, N. H. Ma, E. S. Tzanakakis, A. P. McMahon, P.-T. Chuang, and M. Hebrok Combined activities of hedgehog signaling inhibitors regulate pancreas development Development, October 15, 2003; 130(20): 4871 - 4879. [Abstract] [Full Text] [PDF]

				K. S. Pappu, R. Chen, B. W. Middlebrooks, C. Woo, U. Heberlein, and G. Mardon Mechanism of hedgehog signaling during Drosophila eye development Development, July 1, 2003; 130(13): 3053 - 3062. [Abstract] [Full Text] [PDF]

				E. Roessler and M. Muenke How a Hedgehog might see holoprosencephaly Hum. Mol. Genet., April 2, 2003; 12(90001): R15 - 25. [Abstract] [Full Text] [PDF]

				A.-M. Pulichino, S. Vallette-Kasic, J. P.-Y. Tsai, C. Couture, Y. Gauthier, and J. Drouin Tpit determines alternate fates during pituitary cell differentiation Genes & Dev., March 15, 2003; 17(6): 738 - 747. [Abstract] [Full Text] [PDF]

				L. E. Olson, J. S. Dasen, B. Gun Ju, J. Tollkuhn, and M. G. Rosenfeld Paired-like Repression/Activation in Pituitary Development Recent Prog. Horm. Res., January 1, 2003; 58(1): 249 - 261. [Abstract] [Full Text] [PDF]

				J. Aubin, U. Dery, M. Lemieux, P. Chailler, and L. Jeannotte Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling Development, September 1, 2002; 129(17): 4075 - 4087. [Abstract] [Full Text] [PDF]

				J. A. Lowrey, G. A. Stewart, S. Lindey, G. F. Hoyne, M. J. Dallman, S. E. M. Howie, and J. R. Lamb Sonic Hedgehog Promotes Cell Cycle Progression in Activated Peripheral CD4+ T Lymphocytes J. Immunol., August 15, 2002; 169(4): 1869 - 1875. [Abstract] [Full Text] [PDF]

				L. E. Olson and M. G. Rosenfeld Perspective: Genetic and Genomic Approaches in Elucidating Mechanisms of Pituitary Development Endocrinology, June 1, 2002; 143(6): 2007 - 2011. [Abstract] [Full Text] [PDF]

				K. M. Scully and M. G. Rosenfeld Pituitary Development: Regulatory Codes in Mammalian Organogenesis Science, March 22, 2002; 295(5563): 2231 - 2235. [Abstract] [Full Text] [PDF]

				F. Long, X. M. Zhang, S. Karp, Y. Yang, and A. P. McMahon Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation Development, December 15, 2001; 128(24): 5099 - 5108. [Abstract] [Full Text] [PDF]

				J. S. Dasen, J.-P. M. Barbera, T. S. Herman, S. O' Connell, L. Olson, B. Ju, J. Tollkuhn, S. H. Baek, D. W. Rose, and M. G. Rosenfeld Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis Genes & Dev., December 1, 2001; 15(23): 3193 - 3207. [Abstract] [Full Text] [PDF]

				Z. M. Varga, A. Amores, K. E. Lewis, Y.-L. Yan, J. H. Postlethwait, J. S. Eisen, and M. Westerfield Zebrafish smoothened functions in ventral neural tube specification and axon tract formation Development, September 15, 2001; 128(18): 3497 - 3509. [Abstract] [Full Text] [PDF]