The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4

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				M. Irimia, I. Maeso, and J. Garcia-Fernandez Convergent Evolution of Clustering of Iroquois Homeobox Genes across Metazoans Mol. Biol. Evol., August 1, 2008; 25(8): 1521 - 1525. [Abstract] [Full Text] [PDF]

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				J.M. Ordway, J.A. Bedell, R.W. Citek, A. Nunberg, A. Garrido, R. Kendall, J.R. Stevens, D. Cao, R.W. Doerge, Y. Korshunova, et al. Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets Carcinogenesis, December 1, 2006; 27(12): 2409 - 2423. [Abstract] [Full Text] [PDF]

				M. van Tuyl, J. Liu, F. Groenman, R. Ridsdale, R. N. N. Han, V. Venkatesh, D. Tibboel, and M. Post Iroquois genes influence proximo-distal morphogenesis during rat lung development Am J Physiol Lung Cell Mol Physiol, April 1, 2006; 290(4): L777 - L789. [Abstract] [Full Text] [PDF]

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				A. Glavic, F. Silva, M. J. Aybar, F. Bastidas, and R. Mayor Interplay between Notch signaling and the homeoprotein Xiro1 is required for neural crest induction in Xenopus embryos Development, January 15, 2004; 131(2): 347 - 359. [Abstract] [Full Text] [PDF]

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				A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]

				F. Cavodeassi, J. Modolell, and J. L. Gomez-Skarmeta The Iroquois family of genes: from body building to neural patterning Development, August 1, 2001; 128(15): 2847 - 2855. [Abstract] [Full Text] [PDF]